2010 (41 POSTS)
Greene N , Aleo MD, Louise-May S, Price DA, Will Y. 2010. Using an in vitro cytotoxicity assay to aid in compound selection for in vivo safety studies. Bioorg Med Chem Lett 20(17):5308-5312; doi: 10.1016/j.bmcl.2010.06.129 . PMID: 20655216.
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Topics: computational toxicology , drug development
Racz L , Datta T, Goel RK. 2010. Effect of organic carbon on ammonia oxidizing bacteria in a mixed culture. Bioresour Technol 101(16):6454–6460; doi: 10.1016/j.biortech.2010.03.058 . PMID: 20371177.
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Topics: ammonium
Chernoff N, Rogers JM . 2010. Hypoxia and the edema syndrome: Elucidation of a mechanism of teratogenesis. Birth Defects Res B 89(4):300–303; doi: 10.1002/bdrb.20258 . PMID: 20593454.
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Topics: reproductive toxicology
Gatto NM, Kelsh MA , Mai DH, Suh M , Proctor DM . 2010. Occupational exposure to hexavalent chromium and cancers of the gastrointestinal tract: A meta-analysis. Cancer Epidemiol 34(4):388-399; doi: 10.1016/j.canep.2010.03.013 . PMID: 20430714.
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Topics: Cancer , chromium , Occupational
Sheehan P, Bogen KT, Hicks J, Goswami E, Brorby G , Lau E, Ott B. 2010. Benzene inhalation of parts washers: New estimates based on measures of occupational exposure to solvent coaromatics. Risk Analysis 30(8):1249–1267; doi: 10.1111/j.1539-6924.2010.01412.x . PMID: 20477986.
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Topics: benzene , Exposure Assessment , Occupational
Greene N , Fisk L, Naven RT, Note RR, Patel ML, Pelletier DJ. 2010. Developing structure-activity relationships for the prediction of hepatotoxicity. Chem Res Toxicol 23(7):1215-1222; doi: 10.1021/tx1000865 . PMID: 20553011.
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Topics: drug development
Gillespie BW, Chen Q, Reichert H , Franzblau A, Hedgeman E, Lepkowski J, Adriaens P, Demond A, et al. 2010. Estimating population distributions when some data are below a limit of detection by using a reverse Kaplan-Meier estimator. Epidemiology 21 (Suppl 4):S64-S70; doi: 10.1097/EDE.0b013e3181ce9f08 . PMID: 20386104.
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Topics: Epidemiology
Naven RT, Louise-May S, Greene N . 2010. The computational prediction of genotoxicity. Exp Opin Drug Metabol Toxicol 6(7):1-11; doi: 10.1517/17425255.2010.495118 . PMID: 20528613.
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Topics: carcinogens , computational toxicology , genotoxicity
Gaffney SH, Burns AM, Kreider ML, Unice KM, Widner TE, Paustenbach DJ, Booher LE, Gelatt RN, Panko JM . 2010. Occupational exposure to benzene at the ExxonMobil refinery in Beaumont, TX (1976-2007). Int J Hyg Environ Health 213(4):285–301; doi: 10.1016/j.ijheh.2010.04.004 . PMID: 20494616.
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Topics: benzene , Exposure Assessment , Occupational , Refineries
Olchanski N, Slawsky KA, Plent S, Kado C, Cyr PL . 2010. Economic impact of switching to bivalirudin for a primary percutaneous coronary intervention in a U.S. hospital. Hosp Prac 38(4):138-146; doi: 10.3810/hp.2010.11.351 .
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Topics: Health Economics and Outcomes Research (HEOR)
Goodsaid FM, Amur S, Aubrecht J, Burczynski ME, Catalano J, Carl K, Charlab C,…, Robison TW , et al. 2010. Voluntary exploratory data submissions to the US FDA and the EMA: Experience and impact. Nat Rev Drug Discover 9(6):435-45; doi: 10.1038/nrd3116 . PMID: 20514070.
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Topics: biomarkers , drug development
Shepard TH, Barr M Jr, Brent RL, Hendrickx A, Kochhar D, Oakley G, Scott WJ Jr, Rogers JM . 2010. An updated history of the Teratology Society. Birth Defects Res A 88(5):263–285; doi: 10.1002/bdra.20669 . PMID: 20506459.
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Topics: collaboration , reproductive toxicology
Tachovsky JA, Urban JD , Wikoff DS , Haws LC , Harris MA. 2010. Reduction of a large fish tissue analyte database: Identifying and assessing data specific to a remediation site for risk assessment application. Chemosphere 80(5):481-488; doi: 10.1016/j.chemosphere.2010.04.072 . PMID: 20553933.
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Topics: remediation , risk assessment
Racz L , Datta T, Goel RK. 2010. Organic carbon effect on nitrifying bacteria in a mixed culture. Water Sci Technol 61(11):2951–2956; doi: 10.2166/wst.2010.061 . PMID: 20489269.
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Topics: Environmental Science
Racz L , Goel RK. 2010. Fate and removal of estrogens from municipal wastewater. J Environ Monit 12(1):58–70; doi: 10.1039/b917298j .
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Topics: Environmental Science , water
Sistare FD, Dieterle F, Troth S, Holder DJ, Gerhold D, …, Collins N , et al. 2010. Towards consensus practices to qualify safety biomarkers for use in early drug development. Nat Biotechnol 28(5):446–454; doi: 10.1038/nbt.1634 . PMID: 20458314.
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Topics: biomarkers , drug development
Dieterle F, Sistare F, Goodsaid F, Papaluca M, Ozer JS,…, Collins N , et al. 2010. Renal biomarker qualification submission: A dialog between the FDA-EMEA and Predictive Safety Testing Consortium. Nat Biotechnol 28(5):455–462; doi: 10.1038/nbt.1625 . PMID: 20458315.
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Topics: biomarkers
Rowlands CJ, Staskal DF , Gollapudi B, Budinsky R. 2010. The human AHR: Identification of single nucleotide polymorphisms from six ethnic populations. Pharmacogenet Genom 20(5):283-290; doi: 10.1097/fpc.0b013e32833605f8 . PMID: 20401977.
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