2023 (60 POSTS)
Maloney EM, Villeneuve DL, Jensen KM, Blackwell BR, Kahl MD, Poole ST, Vitense K, Feifarek, DJ, Patlewicz G , et al. 2023. Evaluation of complex mixture toxicity: An experimental and database-driven analysis in the Milwaukee estuary (WI, USA) using whole-mixture and component-based evaluation methods. Environ Toxicol Chem 42(6):1229-1256; doi: 10.1002/etc.5571 . PMID: 36715369.
View Abstract
Topics: ecotoxicology
Henderson RG , Franke KS , Payne LE, Franzen A . 2023. Cannabidiol safety data: A systematic mapping study. Cannabis Cannabinoid Res 8(1):34–40; doi: 10.1089/can.2022.0100 . PMID: 36251454.
View Abstract
Topics: Cannabinoid/Industrial Hemp , Systematic Review
Li H, Krall JR, Frankenfeld C , Slavin M. 2023. Nutritional intake of riboflavin (vitamin B2) and probable migraine: A cross-sectional analysis of the National Health and Nutrition Examination Survey (NHANES) 2001-2004. Nutr Neurosci 26(11):1068-1077; doi: https://doi.org/10.1080/1028415X.2022.2126760 . PMID: 36175363.
View Abstract
Topics: Epidemiology , Food science
Henderson RG , Lefever TW, Heintz MM , Trexler KR, Borghoff SJ , Bonn-Miller MO. 2023. Oral toxicity evaluation of cannabidiol. Food Chem Toxicol 176(June):113786; doi: 10.1016/j.fct.2023.113778 . PMID: 37105391.
View Abstract
Topics: Cannabinoid/Industrial Hemp
Henderson RG , Welsh BT, Rogers JM , Borghoff SJ , Trexler KR, Bonn-Miller MO, Lefever TW. 2023. Reproductive and developmental toxicity evaluation of cannabidiol. Food Chem Toxicol 176(June):113786; doi: 10.1016/j.fct.2023.113786 . PMID: 37105390.
View Abstract
Topics: Cannabinoid/Industrial Hemp
Henderson RG , Welsh BT, Trexler KR, Bonn-Miller MO, Lefever TW. 2023. Genotoxicity evaluation of cannabidiol. Regul Toxicol Pharmacol 142(August):105425; doi: 10.1016/j.yrtph.2023.105425 . PMID: 37271419.
View Abstract
Topics: Cannabinoid/Industrial Hemp , genotoxicity
Nyffeler J, Willis C, Harris FR, Foster MJ, Chambers B, Culbreth M, Brockway RE,…, Patlewicz G , et al. 2023. Application of cell painting for chemical hazard evaluation in support of screening-level chemical assessments. Toxicol Appl Pharmacol 468(June 1):116513; doi: 10.1016/j.taap.2023.116513 . PMID: 37044265.
View Abstract
Topics: chemical safety assessment
Rogers JM, Heintz MM, Thompson CM, Haws LC . 2023. A putative adverse outcome network for neonatal mortality and lower birth weight in rodents: Applicability to per- and polyfluoroalkyl substances and relevance to human health. Birth Defects Res 115(11)1011-1062; doi: 10.1002/bdr2.2185 . PMID: 37219003.
View Abstract
Topics: PFAS
Patlewicz G , Paul Friedman K, Houck K, Zhang L, Huang R, Xia M, Brown J, Simmons SO. 2023. Evaluating the utility of a high throughput thiol-containing fluorescent probe to screen for reactivity: A case study with the Tox21 library. Comput Toxicol 26(May):100271; doi: 10.1016/j.comtox.2023.100271 . PMID: 37388277.
View Abstract
Topics: modeling
Du H, Pan B, Alund AW, Yan J, Chen Y, Robison TW , Chen T. 2023. Evaluation of mutagenic susceptibility of different stages in germ cell development of Caenorhabditis elegans using whole genome sequencing. Arch Toxicol 97(8):2261-2272; doi: 10.1007/s00204-023-03526-z .
View Abstract
Buerger AN , Massarsky A, Russell A, Zoghby N, Hirn C, Mucs D, et al. 2023. Evaluation of chemical grouping workflows for flavor inhalation risk assessment: Selected furan moiety-containing chemicals as a case study. Comp Tox 26(May):100269; doi: 10.1016/j.comtox.2023.100269 .
View Abstract
Topics: risk assessment
Meek ME, Wikoff D . 2023. The need for good practice in the application of mechanistic constructs in hazard and risk assessment. Toxicol Sci 194(1):13-22; doi: 10.1093/toxsci/kfad039 . PMID: 3707944.
View Abstract
Topics: risk assessment
Kaurani P, Hindocha AD, Jayasinghe RM, Pai UY, Batra K, Price C . 2023. Effect of addition of titanium dioxide nanoparticles on the antimicrobial properties, surface roughness and surface hardness of polymethyl methacrylate: A systematic review. F1000Res 12:577; doi: 10.12688/f1000research.130028.1 .
View Abstract
Topics: nanomaterials , Systematic Review , titanium dioxide
Wheeler MW . 2023. An investigation of non-informative priors for Bayesian dose-response modeling. Regul Toxicol Pharmacol 141(June):105389; doi: 10.1016/j.yrtph.2023.105389 . PMCID: PMC10436774.
View Abstract
Topics: dose-response , modeling
Dalvi T, Nørgaard M, Fryzek JP, Movva N , Pedersen L, Hansen HP, et al. 2023. Biomarker expression and survival in patients with non-small cell lung cancer receiving adjuvant chemotherapy in Denmark. PLoS ONE 18(4):e0284037; doi: 10.1371/journal.pone.0284037 . PMID: 37040387.
View Abstract
Topics: Cancer , Epidemiology
Thompson CM , Heintz MM , Wolf JC, Cheru R, Haws LC , Cullen JM. 2023. Assessment of mouse liver histopathology following exposure to HFPO-DA with emphasis on understanding mechanisms of hepatocellular death. Toxicol Pathol 51(1–2):4–14; doi: 10.1177/01926233231159078 . PMID: 36987989.
View Abstract
Topics: ammonium , Exposure Assessment , PFAS
Heintz MM , Haws LC , Klaunig JE, Cullen JM, Thompson CM . 2023. Assessment of the mode of action underlying development of liver lesions in mice following oral exposure to HFPO-DA and relevance to humans. Toxicol Sci 192(1):15–29; doi: 10.1093/toxic/kfad004 . PMID: 36629480.
View Abstract
Topics: Cancer , mode of action , PFAS
Richard AM, Lougee R, Adams M, Hidle H, Yang C, Rathman J, Magdziarz T, Bienfait B, Williams AJ, Patlewicz G . 2023. A new CSRML structure-based fingerprint method for profiling and categorizing per- and polyfluoroalkyl substances (PFAS). Chem Res Toxicol 36(3):508–534; doi: 10.1021/acs.chemrestox.2c00403 . PMID: 36862450.
View Abstract
Topics: PFAS
Carstens KE, Freudenrich T, Wallace K, Choo S, Carpenter A, Smeltz M, Clifton MS,…, Patlewicz G , et al. 2023. Evaluation of per- and polyfluoroalkyl substances (PFAS) in vitro toxicity testing for developmental neurotoxicity. Chem Res Toxicol 36(3):402–419; doi: 10.1021/acs.chemrestox.2c00344 . PMID: 36821828.
View Abstract
Topics: PFAS
Thompson CM , Proctor DM , Harris MA. 2023. Letter to “Chepelev et al. Establishing a quantitative framework for regulatory interpretation of genetic toxicity dose–response data: Margin of exposure case study of 48 compounds with both in vivo mutagenicity and carcinogenicity dose–response data.” Environ Mol Mutagen 64(4):259–260; doi: 10.1002/em.22537 . PMID: 36916184.