2025 (98 POSTS)
Verwiel A , Rish W . 2025. Multidisciplinary perspectives on cumulative impact assessment for vulnerable communities: Expert elicitation using a Delphi method. Integr Environ Assess Manag 21(2):301-313; doi: 10.1093/inteam/vjae051 . PMID: 39881570.
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Publication: Manuscripts
/ Topics: Air Quality , risk assessment
Wikoff D . Use cases of strategic application of ML/AI in the risk assessment process. Toxicology Forum 2025 Winter Meeting, Raleigh, NC, February 2025.
Publication: Abstracts and Presentations
/ Topics: Food science , risk assessment
Wikoff D . Pragmatic solutions for better using evidence-based methods to integrate observational data in food safety assessments. Toxicology Forum 2025 Winter Meeting, Raleigh, NC, February 2025.
Publication: Abstracts and Presentations
/ Topics: Food science , risk assessment
Lagiakos HR, Zou Y, Igawa H, Therrien E, Lawrenz M, Kato M, Svensson M, Gray F, Jensen K, Dahlgren M, Pelletier R, Dingley K, et al. 2025. In silico enabled discovery of KAI-11101, a preclinical DLK inhibitor for the treatment of neurodegenerative disease and neuronal injury. J Med Chem 68(3):2720-2741; doi: 10.1021/acs.jmedchem.4c02074 . PMID: 39670820.
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Publication: Manuscripts
Payton A, Hickman, Chappel J, Roell KR, Koval LA, Eaves LA, Chou CK,…, Patlewicz G , et al. 2025. TAME 2.0: Expanding and improving online data science training for environmental health research. Front Toxicol 7(Feb 12):1535098; doi: 10.3389/ftox.2025.1535098 . PMID: 40012886.
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Publication: Manuscripts
/ Topics: Exposure Assessment
Borghoff SJ, Rivera B, Fitch S, Buerger AN, Choksi N, Franzen A, Vincent MJ, Covington T, Bus J, Rushton E, Lea IA . 2025. Systematic evaluation of the evidence base on methyl tert -butyl ether supporting a lack of concern for carcinogenic hazard in human based on animal cancer studies and mechanistic data. Curr Res Toxicol 8:100224; doi: 10.1016/j.crtox.2025.100224 . PMID: 40084233.
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Publication: Manuscripts
/ Topics: Cancer , carcinogens , MTBE , risk assessment
Rogers JM, Buerger AN , Heintz MM , Palermo CM, Haws LC, Lea IA . 2025. Evaluation of a hypothesized Sertoli cell-based adverse outcome pathway for effects of diisononyl phthalate on the developing testis. Curr Res Toxicol 8:100219; doi: 10.1016/j.crtox.2025.100219 . PMID: 40123861.
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Publication: Manuscripts
/ Topics: phthalates
Lea IA , Buerger AN , Feifarek D, Mihalchik A, Heintz MM, Haws LC , Nyambego H, Goyak K, Palermo C, Borghoff SJ . 2025. Evaluation of the endocrine disrupting potential of Di-isononyl phthalate. Curr Res Toxicol 8:100220; doi: 10.1016/j.crtox.2025.100220 . PMID: 40092461. Corrigendum 8:100233; doi: 10.1016/j.crtox.2025.100233 ; PMID 40529321.
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Publication: Manuscripts
/ Topics: phthalates
Moyer HL , Vergara L, Stephan C, Sakolish C, Ford LC, Tsai HD, Lin HC, Chiu WA, et al. 2025. Comparative analysis of caco-2 cells and human jejunal and duodenal enteroid-derived cells in gel- and membrane-based barrier models of intestinal permeability. Toxicol Sci 204(2):181-197; doi: 10.1093/toxsci/kfaf011 . PMID: 39886939.
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Publication: Manuscripts
/ Topics: modeling
Kennedy SB, Heintz MM, Klaren WD, Wikoff DS, Haws LC, Fitch SE . 2025. An integrated ecotoxicological study reliability framework for use in toxicity value development. Environ Tox Chem 44(4):1142-1153; doi: 10.1093/etojnl/vgaf030 . PMID: 39873747.
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Publication: Manuscripts
/ Topics: ecotoxicology , risk assessment
Schaefer HR , Vincent MJ , Burns CJ, Lange SS. 2025. Increasing the utility of epidemiologic studies as key evidence in chemical risk assessment. Toxicol Sci 203(2):166-170; doi: 10.1093/toxsci/kfae134 . PMID: 39657235.
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Publication: Manuscripts
/ Topics: Epidemiology , risk assessment
Patlewicz G , Williams AJ, Adams M, Shah I, Paul-Friedman K. 2025. A cheminformatics workflow to select representative TSCA chemicals for New Approach Methodology (NAM) screening. Chem Res Toxicol 38(1):129-144; doi: 10.1021/acs.chemrestox.4c00367 . PMID: 39655894.
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Publication: Manuscripts
/ Topics: NAMs
Shafrin J, Wang S, Sharma K, Spurrier K, Nordyke RJ . 2025. Will the Institute for Clinical and Economic Review’s shared savings approach decrease value-based prices most for the most severe diseases? Value Health 28(1):25-30; doi: 10.1016/j.val.2024.09.002 . PMID: 39357669.
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Publication: Manuscripts
/ Topics: Health Economics and Outcomes Research (HEOR)
Patterson JA, Motyka J, Salih R, Nordyke RJ , O’Brien JM, Campbell JD. 2025. Subsequent indications in oncology drugs: Pathways, timelines, and the Inflation Reduction Act. Ther Innov Regul Sci 59(1):102-111; doi: 10.1007/s43441-024-00706-6 . PMID: 39369117.
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Publication: Manuscripts
/ Topics: drug development
Sakolish C, Moyer HL , Tsai HD, Ford LC, Dickey AN, Bajaj P, Villenave R, Hewitt P, et al. 2025. Comparative analysis of the physiological and transport functions of various sources of renal proximal tubule cells under static and fluidic conditions in PhysioMimix T12 platform. Drug Metab Dispos 53(1):10001; doi: 10.1124/dmd.124.001488 . PMID: 39884810.
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Publication: Manuscripts
/ Topics: pharmacokinetics
Zilber D, Messier KP, House J, Parham F, Auerbach SS, Wheeler MW . 2025. Bayesian gene set benchmark dose estimation for “omic” responses. Bioinformatics 41(1):btaf008; doi: 10.1093/bioinformatics/btaf008 . PMCID: PMC11783320.
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Publication: Manuscripts
/ Topics: Bayesian modeling , benchmark dose estimation (BMD) , transcriptomics
Rana Z, Frankenfeld CL , Kennedy E, Bertoldi J, de Jonge E, Cheskin L. 2025. Food sources of energy and nutrients among US college students: The Health Starts Here cohort study. J Am Coll Health 73(1):301-310; doi: 10.1080/07448481.2023.2220397 . PMID: 37290009.
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Publication: Manuscripts
/ Topics: Epidemiology , Food science
Lipworth L, Panko JM , Allen BC, Mumma MT, Jiang X , Vincent MJ , Bare JL , Antonijevic T, Vivanco SN , Marano DE, Suh M , Cohen S, Mittal L , Proctor DM . 2025. Lung cancer mortality among aircraft manufacturing workers with long-term, low-level, hexavalent chromium exposure. J Occup Environ Hyg 22(3):214-227 ; doi: 10.1080/15459624.2024.2439817 . PMID: 39773194.
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Publication: Manuscripts
/ Topics: Cancer , chromium , Exposure Assessment , Occupational
2024 (155 POSTS)
Wikoff D , Fitch S . 2024. Systematic reviews and evidence-based methods in toxicology. In: Wexler P (ed), Encyclopedia of Toxicology. Elsevier, pp. 875–882.
Publication: Book Chapters
/ Topics: evidence-based reviews , Systematic Review
Kim A, Cong Z, Jazieh A-R, Church TR, Reichert H , Nicholson G, Fryzek J, Cohen SS. 2024. Estimating the incremental population health impact of a multi-cancer early detection (MCED) test to complement existing screening among elevated risk populations with multiple cancer risk factors: A mathematical modeling study. BMC Health Serv Res 24(1):1584; doi: 10.1186/s12913-024-12037-1 . PMID: 39695574.
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