2025 (136 POSTS)
Patlewicz G , Charest N, Ross A, Bledsoe HC, Vidal J, Faramarzi S, Hagan B, Shah I. 2025. Building a compendium of expert driven read-across cases to facilitate an analysis of the contribution that different similarity contexts play in read-across performance. Comput Toxicol 35(Sept):100366; doi: 10.1016/j.comtox.2025.100366 .
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Publication: Manuscripts
/ Topics: NAMs
Racz L , Hale A . 2025. An integrated approach to planning for and responding to ionizing radiation incidents. Chapter 13 in: Racz L and Badiru AB (eds), Handbook of Emergency Response: A Human Factors and Systems Engineering Approach, 2nd Edition. Taylor and Francis Group—CRC Press: Boca Raton, FL. pp. 240-256; doi: 10.1201/9781003648178 .
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Publication: Book Chapters
/ Topics: Radiation
Desai NR, Fermann G, Pollack C, Venkatesh A, Hooda N , Jiang X , Sacks N , Holtz A, et al. Emergency department visits for PSVT: An analysis of the HCUP Nationwide Emergency Department Sample. Abstract 391, American College of Emergency Physicians (ACEP) Research Forum. Ann Emerg Med 86(3S1):S169; doi: 10.1016/j.annemergmed.2025.06.409 . Salt Lake City, UT, September 2025.
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Publication: Abstracts and Presentations
/ Topics: Health Economics and Outcomes Research (HEOR)
Mease K . High safety bar, low safety margin case studies. Presented at 29th Annual Charles River Biotech Symposium, Carlsbad, CA, September 8-10, 2025.
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Publication: Abstracts and Presentations
/ Topics: drug development , nonclinical safety assessment
Nyffeler J, Harris FR, Willis C, Byrd G, Blackwell B, Escher BI, Kasparek A, Nichols J,…, Patlewicz G , et al. 2025. A combination of high-throughput in vitro and in silico new approach methods (NAMs) for ecotoxicology hazard assessment for fish. Environ Toxicol Chem 44(9):2599-2621; doi: 10.1093/etojnl/vgae083 . PMID: 39937625.
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Publication: Manuscripts
/ Topics: ecotoxicology , NAMs
Baldwin WS, Bloom MS, Chung KW, Dasgupta S, DeLorenzo ME, Hunt KJ, Key PB,…, Jacobellis MA , et al. 2025. Toxicological, chemical, social, and economic challenges associated with PFAS and replacement aqueous film-forming foams (AFFF). Toxics 13(9):732; doi: 10.3390/toxics13090732 . PMID: 41012353.
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Publication: Manuscripts
/ Topics: PFAS
Redman AD, Key T, Koster van Groos P, Smith A, Sutherland C, Reddington T, Kung M , Davis C, et al. 2025. Integrated assessment of whole effluent toxicity tests and chemical characterization of treated Permian basin produced water. ACS ES&T Water 5(9):5275-5286; doi: 10.1021/acsestwater.5c00389 .
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Publication: Manuscripts
/ Topics: ecotoxicology , risk assessment , water
Karamertzanis PG, Rasenberg M, Shah I, Patlewicz G . 2025. Modelling in vitro mutagenicity using multi-task deep learning and REACH data. Chem Res Toxicol 38(8):1382-1407; doi: 19.1021/acs.chemrestox.5c00152 . PMID: 40680271.
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Publication: Manuscripts
/ Topics: modeling , regulatory toxicology
Shaw J, Hsu H, Tu H, Chia V, Aggarwal S, Carrigan G, Kelsh MA . Immortal time bias impacts time-to-time event outcomes in cohort with genomic testing. Abstract 6F-03, International Society for Pharmacoepidemiology (ISPE) 41st Annual Meeting, Washington, DC, August 2025.
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Publication: Abstracts and Presentations
/ Topics: Cancer , Epidemiology
Righter R, Yale K , Stewart C, Marshall L, Fairbanks H. Methods in qualitative data analysis to progress community health equity. Abstract 3993/Poster EP02-18, International Society of Exposure Science and International Society for Environmental Epidemiology (ISES/ISEE) Joint Annual Meeting, Atlanta, GA, August 2025 .
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Publication: Abstracts and Presentations
/ Topics: community health
Rish W , Verwiel A. Importance of epidemiology and visualization to integrate non-chemical stressors into cumulative impact assessment for vulnerable communities. Abstract 568/Poster P47-17, International Society of Exposure Science and International Society for Environmental Epidemiology (ISES/ISEE) Joint Annual Meeting, Atlanta, GA, August 2025 .
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Publication: Abstracts and Presentations
/ Topics: chemical safety assessment , community health , Epidemiology , Exposure Assessment
Muller K, Unice K, Panko J , Ferrari BJD, Breider F, Wagner S. 2025. Risk assessment of tire wear in the environment—A literature review. Environ Sci Process Impacts 27(8):2212-2232; doi: 10.1039/d5em00088b . PMID: 40569214.
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Publication: Manuscripts
/ Topics: ecotoxicology , Environmental Science , leachables , risk assessment , tire particles (TRWP)
Moyer HL , Vergara L, Stephan C, Sakolish C, Lin HC, Chiu WA, Villenave R, Hewitt P, et al. 2025. Human small intestinal tissue models to assess barrier permeability: Comparative analysis of caco-2 cells, jejunal and duodenal enteroid-derived cells, and EpiIntestinalTM tissues in membrane-based cultures with and without flow. Bioengineering (Basel) 12(8):809; doi: 10.3390/bioengineering12080809 . PMID: 40868322.
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Publication: Manuscripts
/ Topics: NAMs
Clouser MC, Suh M , Movva N , Hildebrand JS, Pastula ST, Schoehl M, Hindoyan A, Balasubramanian A, et al. 2025. A systematic literature review of MTAP deletions in solid and hematologic cancers. Cancer Treat Res Comm 44:100966; doi: 10.1016/j.ctarc.2025.100966 . PMID: 40729867.
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Publication: Manuscripts
/ Topics: Cancer , Systematic Review
Sidhu MK, Miller B , Jensen I , Rabiner P. 2025. Abstract EE171: Conceptual framework for a de novo cost-effectiveness model in glycogen storage disease type Ia (GSDIa). Value in Health 28(6-Sup1):S93-S94; doi: 10.1016/j.jval.2025.04.463 .
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Publication: Abstracts and Presentations
/ Topics: Health Economics and Outcomes Research (HEOR)
Monticello TM , MacLachlan TK, Funk KA, Rock BM, Bussiere JL, Grieves JL, Schuh JCL, Henry S. 2025. Nonclinical safety assessment: An overview of drug and medical device development. Chapter 1 in: Bouchard PR, Sahota PS, Wallace S, Wojcinski ZW, Schumacher VL (eds), Toxicologic Pathology: Nonclinical Safety Assessment, 3rd edition. Boca Raton: CRC Press-Taylor and Francis Group. pp. 3-51.
Publication: Book Chapters
/ Topics: drug development , nonclinical safety assessment
Kenyon EM, DeVito MJ, Patlewicz G , Adams LD, Thomas RS, Ambroso JL, Yang X, Blake JC, et al. 2025. Subchronic toxicity of four per- and polyfluoroalkyl substances by oral exposure in Sprague Dawley rats. Toxics 13(7):524; doi: 10.3390/toxics13070524 . PMID: 40710969.
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Publication: Manuscripts
/ Topics: PFAS
Leary A, Shah I, Patlewicz G . 2025. An exploration of the use of hybrid fingerprints in Generalized Read-Across and their impact on predictive performance for selected in vivo toxicity outcomes. Comput Toxicol 34(June):100349; doi: 10.1016/j.comtox.2025.100349 .
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