Publications

Caballero-Gallardo K, Wirbisky-Hershberger S, Olivero-Verbel J, de la Rosa J, Freeman JL. 2018. Embryonic exposure to an aqueous coal dust extract results in gene expression alterations associated with development and function of connective tissue and the hematological system, immunological and inflammatory disease and cancer in zebrafish. Metallomics 10(3):463–473

Zhou W, Pal AS, Hsu AY, Gurol T, Zhu X, Wirbisky-Hershberger SE, Freeman JL, Kasinski AL, Deng Q. 2018. MicroRNA-223 supresses the canonical NF-kB pathway basal keratinocytes to dampen neutrophilic inflammation. Cell Reprod 13:1810–1823.

Wirbisky-Hershberger SE, Sanchez OF, Horzmann KA, Thanki D, Yuan C, Freeman JL. 2017. Atrazine exposure decreases the activity of DNMTs, global DNA methylation levels, and dnmt expression. Food Chem Toxicol 109:727–734.

Wirbisky SE, Freeman JL. 2017. Atrazine exposure elicits copy number alterations in the zebrafish genome. Comp Biochem Physiol C Toxicol Pharmacol 194:1–8.

Cui Y, Li J, Weng L, Wirbisky SE, Freeman JL, Liu J, Liu Q, Yuan X, Irudayaraj J. 2016. Regulatory landscape and clinical implication of MBD3 in human malignant glioma. Oncotarget 7(49):81698–81714.

Wirbisky SE, Weber GJ, Schlotman KE, Sepúlveda MS, Freeman JL. 2016. Embryonic atrazine exposure alters zebrafish and human miRNAs associated with angiogenesis, cancer, and neurodevelopment. Food Chem Toxicol 98:25–33.

Wirbisky SE, Sepúlveda MS, Weber GJ, Jannasch AS, Horzmann KA, Freeman JL. 2016. Embryonic atrazine exposure elicits alterations in genes associated with neuroendocrine function in adult male zebrafish. Toxicol Sci 153:149–164.

Bi P, Yue F, Karki A, Castro B, Wirbisky SE, Wang C, … Kuang, S. 2016. Notch activation drives adipocyte dedifferentiation and tumorigenic transformation in mice. J Exp Med 213(10):2019–2037.

Bi P, Yue F, Sato Y, Wirbisky S, Liu W, Shan T, Wen Y, Zhou D, Freeman J, Kuang S. 2016. Stage-specific effects of notch activation during skeletal myogenesis. Elife 5:e17355.

Wirbisky SE, Weber GJ, Sepúlveda MS, Lin TL, Jannasch AS, Freeman JL. 2016. An embryonic atrazine exposure results in reproductive dysfunction in adult zebrafish and morphological alterations in their offspring. Sci Rep 19:21337, doi 10.1038/srep21337.

Wirbisky SE, Damayanti NP, Mahapatra CT, Sepúlveda MS, Irudayaraj J, Freeman JL. 2016. Mitochondrial dysfunction, disruption of F-actin polymerization, and transcriptomic alterations in zebrafish larvae exposed to trichloroethylene. Chem Res Toxicol 29:169–179.

Wirbisky SE, Freeman JL. 2015. Atrazine exposure and reproductive dysfunction through the hypothalamus-pituitary-gonadal (HPG) axis. Toxics 3:414–450.

Wirbisky SE, Weber GJ, Sepúlveda MS, Xiao C, Cannon JR, Freeman JL. 2015. Developmental origins of neurotransmitter and transcriptome alterations in adult female zebrafish exposed to atrazine during embryogenesis. Toxicology 333:156–167.

Wirbisky SE, Weber GJ, Lee JW, Cannon JR, Freeman JL. 2014. Novel dose-dependent alterations in excitatory GABA during embryonic development associated with lead (Pb) neurotoxicity. Toxicol Lett 229:1–8.

Schlotman KE, Wirbisky SE, Freeman JL. 2014. An epigenetic look at atrazine toxicity: An analysis of microRNA-126 Expression in developing zebrafish exposed to the herbicide atrazine. J Purdue Undergrad Res 4:Article 8.

Wirbisky SE, Freeman JL. 2014. Using zebrafish to define mechanisms of lead (Pb) developmental neurotoxicity. Chapter 11 in: Lessman CA, Carver EA (eds), Zebrafish: Topics in Reproduction, Toxicology, and Development. Nova Science Pub Inc., 225–244.