Publications

Martini C, Liu Y, Motti D, Johnson J, McCormick K, Lea I, Fostel F. Integrating assay datasets into Chemical Effects in Biological Systems (CEBS). Abstract #1749-P125, Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.

Sheridan ER, Jackson M, Paleja A, Martini C, Rashid A, Lea I, Fostel J. Improved searching in the Chemical Effects in Biological Systems (CEBS) database leads to greater utility of NTP data. Abstract 2525-P887, Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.

Lea I, Yang L, Rashid A, Fostel JM. Benchmark dose analysis of Chemical Effects in Biological Systems (CEBS) datasets. Abstract 2918-P412. Presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.

Martini C, Rashid A, Paleja A, Lea I, Fostel JM. Chemical Effects in Biological Systems (CEBS) database: Treatment-related findings. Abstract 1381-P119. Presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.

Sheridan E, Martini C, Shaw M, Shockley K, Brix A, Rashid A, Lea I, Fostel J. Using the Chemical Effects in Biological Systems (CEBS) database to answer pathology questions. Poster P035. Presented at the 36th Annual Symposium of Society for Toxicologic Pathology, Montreal, Quebec, Canada, June 2017.

Jackson M, Yang L, Yauk CL, Lea I, Kuo B, Williams A, Rashid A, Fostel J. The TGx-28.65 biomarker — A web-based application using transcriptomics to identify DNA damage-inducing chemicals. Abstract 1224. Presented at the 48th Annual Meeting of Environmental Mutagenesis and Genomics Society, Raleigh, NC, September 2017.

Jackson MA, Yang L, Lea I, Rashid A, Kuo B, Williams A, Lyn Yauk C, Fostel J. 2017. The TGx-28 65 biomarker online application for analysis of transcriptomics data to identify DNA damage-inducing chemicals in human cell cultures. Environ Mol Mutagen 58(7):529–535; doi: 10.1002/em.22114.

Lea IA, Gong H, Paleja A, Rashid, A, Foster J. 2017. CEBS: A comprehensive annotated database of toxicological data. Nucleic Acids Res 45(D1):D964–D971; doi: 10.1093/nar/gkw1077.

Lea I, Rashid A, Favaro C, Fostel J. Chemical Effects in Biological Systems (CEBS) database: Advanced histopathology search applications. Abstract 2195-P410. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.

Bhusari S, Malarkey DE, Hong HH, Wang Y, Masinde T, Nolan M, Hooth NJ, Lea IA, Vasconcelos D, Sills RC, Hoenerhoff MJ. 2014. Mutation spectra of Kras and Tp53 in urethral and lung neoplasms in B6C3F1 mice treated with 3,3′,4,4′-tetrachloroazobenzene. Toxicol Pathol 42(3):555–564; doi: 10.1177/0192623313491169.

Waters MD, Jackson MA, Lea IA. 2010. Characterizing and predicting carcinogenicity and mode-of-action using conventional and toxicogenomics methods. Mutat Res 705(3):184–200; doi: 10.1016/j.mrrev.2010.04.005.

Lea IA, Jackson MA, Dunnick JK. 2009. Genetic pathways to colorectal cancer. Mutat Res 670(1–2):96–98; doi: 10.1016/j.mrfmmm.2009.06.011.

Lea IA, Jackson MA, Li X, Bailey S, Peddada SD, Dunnick JK. 2007. Genetic pathways and mutation profiles of human cancers: Site- and exposure-specific patterns. Carcinogenesis 28(9):1851–1858; doi: 10.1093/carcin/bgm176.

Jackson MA, Lea I, Rashid A, Peddada SD, Dunnick JK. 2006. Genetic alterations in cancer knowledge system: Analysis of gene mutations in mouse and human liver and lung tumors. Toxicol Sci 90(2):400–418; doi: 10.1093/toxsci/kfj101.

Lea IA, Widgren EE, O’Rand MG. 2004. Association of sperm protein 17 with A-kinase anchoring protein 3 in flagella. Reprod Biol Endocrinol 2(Jul 16):57; doi: 10.1186/1477-7827-2-57.

Lea IA, Widgren EE, O’Rand MG. 2002. Analysis of recombinant mouse zona pellucida protein 2 (ZP2) constructs for immunocontraception. Vaccine 20(11–12):1515–1523; doi: 10.1016/S0264-410X(01)00514-X.

Lea IA, Sivashanmugam P, O’Rand MG. 2001. Zonadhesin: Characterization, localization, and zona pellucida binding. Biol Reprod 65(6):1691–700; doi: 10.1095/biolreprod65.6.1691.

Lea IA, Kurth B, O’Rand MG. 1998. Immune response to immunization with sperm antigens in the macaque oviduct. Biol Reprod 58(3):794–800; doi: 10.1095/biolreprod58.3.794.

Lea IA, van Lierop MJ, Widgren EE, Grootenhuis A, Wen Y, van Duin M, O’Rand MG. 1998. A chimeric sperm peptide induces antibodies and strain-specific reversible infertility in mice. Biol Reprod 59(3):527-36; doi: 10.1095/biolreprod59.3.527

Lea IA, Adoyo P, O’Rand MG. 1997. Autoimmunogenicity of the human sperm protein Sp17 in vasectomized men and identification of linear B cell epitopes. Fertil Steril 67(2):355–361; doi: 10.1016/S0015-0282(97)81923-1.