2014 (10 POSTS)
Suh M, Troese MJ, Hall DA, Yasso B, Yzenas JJ, Proctor DM . 2014. Evaluation of electric arc furnace-processed steel slag for dermal corrosion, irritation, and sensitization from dermal contact. J Appl Toxicol 34(12):1418-1425; doi: 10.1002/jat.2974 .
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Topics: chromium , Exposure Assessment , nickel , Toxicology
Suh M, Abraham L, Hixon JG, Proctor D . 2014. The effects of perchlorate, nitrate, and thiocyanate on free thyroxine for potentially sensitive subpopulations of the 2001–2002 and 2007–2008 National Health and Nutrition Examination Surveys. J Expos Sci Epidemiol 24(6):579-587; doi: 10.1038/jes.2013.67 .
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Topics: Epidemiology , Exposure Assessment , NHANES
Thompson CM , Kirman CR, Proctor DM , Haws LC , Suh M , Hays S, Hixon JG, Harris MA. 2014. A chronic oral reference dose for hexavalent chromium-induced intestinal cancer. J Appl Toxicol 34:525-536. doi: 10.1002/jat.2907 .
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Topics: Cancer , Hexavalent Chromium
Suh M, Thompson C, Kirman C, Carakostas M, Haws LC, Harris M, Proctor D . 2014. High concentrations of hexavalent chromium in drinking water alter iron homeostasis in F344 rats and B6C3F1 mice. Food Chem Toxicol 65:381-388; doi: 10.1016/j.fct.2014.01.009 .
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Topics: Cr(VI) MOA Study , Hexavalent Chromium
2013 (7 POSTS)
Kirman CR, Aylward LL, Suh M , Harris MA, Thompson CM , Haws LC , Proctor DM , Lin SS, Parker W, Hays SM. 2013. Physiologically based pharmacokinetic model for humans orally exposed to chromium. Chem Biol Interact 204(1):13-27. doi:pii: S0009-2797(13)00082-3. 10.1016/j.cbi.2013.04.003.
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Topics: Cr(VI) MOA Study
O’Brien T, Ding H, Suh M , Thompson C , Parsons BL, Harris MA, Winkelman WA, Wolf JC, Hixon JG, Schwartz AM, Myers MB, Haws LC , Proctor DM. 2013. Assessment of K-Ras mutant frequency and micronucleus incidence in the mouse duodenum following 90-days of exposure to Cr(VI) in drinking water. Mutat Res 754:15-21. doi: 10.1016/j.mrgentox.2013.03.008 .
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Topics: Cr(VI) MOA Study , Hexavalent Chromium
Suh M, Thompson CM, Hixon JG, Harris MA, Kirman CR, Hays S, Haws LC, Proctor DM . 2013. Potential involvement of oxidative stress and iron disturbance in the development of oral cavity tumors in rats exposed to hexavalent chromium. Presented at the Society of Toxicology’s 52nd Annual Meeting, March 10-14, San Antonio, TX.
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Topics: Hexavalent Chromium
Thompson CM , Proctor DM , Suh M , Haws LC , Kirman CR, Harris MA. 2013. Assessment of the mode of action underlying development of rodent small intestinal tumors following oral exposure to hexavalent chromium and relevance to humans. Crit Rev Toxicol 43(3):244-274; doi: 10.3109/10408444.2013.768596 .
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Topics: chromium , Cr(VI) MOA Study , Exposure Assessment , Hexavalent Chromium
Thompson CM, Kirman CR, Proctor DM, Suh M, Hays SM, Haws LC , Harris MA. A chronic oral reference dose for hexavalent chromium. Presented at Society of Toxicology 52nd Annual Meeting, San Antonio, TX, March 2013.
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Topics: Hexavalent Chromium
Proctor DM, Suh M, Thompson CM , Harris MA. 2013. Mode of action evaluation for hexavalent chromium-induced lung cancer. Presented at the Society of Toxicology’s 52nd Annual Meeting, March 10-14, San Antonio, TX.
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Topics: Hexavalent Chromium
Kirman CR, Thompson CM, Proctor DM, Suh M, Haws LC , Harris MA, Hays SM. 2013. Using PBPK modeling to address diurnal variation and age differences in hexavalent chromium toxicokinetics in humans. Presented at Society of Toxicology 52nd Annual Meeting, March 10-14, San Antonio, TX.
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Topics: Hexavalent Chromium , pharmacokinetics
2012 (11 POSTS)
Kirman, CR, Hays, SM, Aylward, LL, Suh, M, Harris, MA, Thompson, CM, Haws, LC, Proctor, DM . 2012. Physiologically based pharmacokinetic model for rats and mice orally exposed to chromium. Chem Biol Interact 200(1):45-64.
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Topics: Cr(VI) MOA Study
Harris MA, Thompson CM , Wolf JC, Fedorov Y, Hixon JG, Proctor DM, Suh M, Haws LC . Assessment of genotoxic potential of Cr(VI) in the intestine via in vivo intestinal micronucleus assay and in vitro high content analysis in differentiated and undifferentiated caco-2. Presented at Society of Toxicology’s 51st Annual Meeting, San Francisco, CA, March 2012.
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Topics: chromium , Cr(VI) MOA Study
Proctor DM , Suh M , Aylward LL, Kirman CR, Harris MA, Thompson CM , Gürleyük H, Gerads R, Haws LC , Hays SM. 2012. Hexavalent chromium reduction kinetics in rodent stomach contents. Chemosphere 89(5):487-493; doi: 10.1016/j.chemosphere.2012.04.065.
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Topics: Cr(VI) MOA Study , Hexavalent Chromium
Hays SM, Kirman C, Aylward L, Suh M , Proctor D . Gastric reduction of Cr(VI) in mice, rats and humans. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.
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Topics: chromium , Hexavalent Chromium , Toxicology
Thompson CM , Fedorov Y, Brown DD, Suh M , Proctor DM, Kuriakose L, Haws L, Harris MA. 2012. Assessment of Cr(VI)-induced cytotoxicity and genotoxicity using high content analysis. PLoS ONE 7(8):e42720; doi: 10.1371/journal.pone.0042720 .
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Topics: Cr(VI) MOA Study , Hexavalent Chromium
Suh M , Ke JG, Hixon G, Proctor DM . Urinary perchlorate, nitrate, thiocyanate and thyroid hormone levels in participants of National Health and Nutrition Examination Survey (NHANES) 2001-2002. Presented at the International Society of Environmental Epidemiology’s 24th Annual Meeting, Columbia, SC, August 2012.
Topics: NHANES , Toxicology
Thompson CM, Hixon JG, Proctor DM, Haws LC, Suh M, Urban JD, Harris MA. 2012. Assessment of genotoxic potential of Cr(VI) in the mouse duodenum: An in silico comparison with mutagenic and nonmutagenic carcinogens across tissues. Regul Toxicol Pharmacol 64(1):68-76; doi: 10.1016/j.yrtph.2012.05.019
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Topics: chromium , Cr(VI) MOA Study
Thompson CM , Proctor DM , Suh M , Haws LC , Hebert CD, Mann JF, Shertzer HG, Hixon JG, Harris MA. 2012. Comparison of the effects of hexavalent chromium in the alimentary canal of F344 rats and B6C3F1 mice following exposure in drinking water: Implications for carcinogenic modes of action. Toxicol Sci 125(1):79-90; doi: 10.1093/toxsci/kfr280 .
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Topics: carcinogens , Cr(VI) MOA Study , Hexavalent Chromium
Kirman CR, Hays SM, Aylward LL, Suh M, Proctor D . 2012. Physiologically-based pharmacokinetic model for mice, rats and humans orally-exposed to chromium. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.
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