2018 (7 POSTS)
Covington TR , Ott DK, Gearhart JM, Pangburn HA. Development of a physiologically-based pharmacokinetic model for the virtual high-performance aircraft pilot. Poster presented at Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.
Publication: Abstracts and Presentations
Haber LT, Dourson ML, Allen BC, Hertzberg RC, Parker A, Vincent MJ , et al. 2018. Benchmark dose (BMD) modeling: Current practice, issues, and challenges. Crit Rev Toxicol 48(5):387–415; doi: 10.1080/10408444.2018.1430121 .
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Publication: Manuscripts
Roberts DW, Patlewicz G . 2018. Non-animal assessment of skin sensitization hazard – Is an integrated testing strategy needed, and if so what should be integrated? J Appl Toxicol 38(1):41-50; doi: 10.1002/jat.3479 . PMID: 28543848.
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Publication: Manuscripts
2017 (8 POSTS)
Bare JL , Abramson MM, Barlow CA, Scott PK. 2017. Use of air dispersion modeling to estimate historical community exposure from manufacturers of asbestos-containing products. Abstract P.96, Society for Risk Analysis (SRA) Annual Meeting, Arlington, VA, December 2017.
Publication: Abstracts and Presentations
Liu J, Patlewicz G , Williams A, Thomas RS, Shah I. 2017. Predicting organ toxicity using in vitro bioactivity data and chemical structure. Chem Res Toxicol 30(11):2046-2059; doi: 10.1021/acs.chemrestox.7b00084 . PMID: 28768096.
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Publication: Manuscripts
Wheeler MW , Bailer AJ, Cole T, Park RM, Shao K. 2017. Bayesian quantile impairment threshold benchmark dose estimation for continuous endpoints. Risk Anal 37(11):2107-18; doi: 10.1111/risa.12762 . PMCID: PMC5740488.
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Publication: Manuscripts
Judson RS, Martin M, Patlewicz G , Wood CE. 2017. Retrospective mining of toxicology data to discover multispecies and chemical class effects: Anemia as a case study. Regul Toxicol Pharmacol 86(June):74-92; doi: 10.1016/j.yrtph.2017.02.015 . PMID: 28242142.
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Publication: Manuscripts
Kirman CR, Suh M, Proctor DM , Hays SM. 2017. Improved physiologically based pharmacokinetic model for oral exposures to chromium in mice, rats, and humans to address temporal variation and sensitive populations. Toxicol Appl Pharmacol 325(15 June):9-17; doi: 10.1016/j.taap.2017.03.023 .
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Publication: Manuscripts
Borghoff SJ , Ring C, Banton MI, Leavens TL. Ethyl tertiary butyl ether (ETBE) and tertiary butyl alcohol (TBA) physiologically based pharmacokinetic (PBPK) model in rats: Contribution of binding to 2u-globulin and non-linear kinetics to kidney and liver responses in rats. Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.
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Publication: Abstracts and Presentations
Kirman CR, Proctor D, Suh M, Haws L, Harris M, Thompson C , Hays S. Using physiologically based pharmacokinetic modeling to address potentially sensitive subpopulations exposed to hexavalent chromium. Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.
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Publication: Abstracts and Presentations
Covington TR , Pangburn HA, Mayes RS, Ott DK, Gearhart JM. Estimated inter-individual variations in high-performance aircraft pilot exposures using physiologically-based pharmacokinetic (PBPK) modeling and Monte Carlo analysis. Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.
Publication: Abstracts and Presentations
2016 (3 POSTS)
Cyrs WD, Dussex D, Glynn M, Finley BL . Benchmark dose modeling for respiratory irritation from 2,3-pentanedione exposure. Podium presentation at American Industrial Hygiene Conference & Exposition (AIHce), 2016.
Publication: Abstracts and Presentations
Covington TR , Lumley LA, Ruark CD, Clarkson ED, Whalley CE, Gearhart JM. 2016. Modeling organophosphorus chemical warfare nerve agents: A physiologically based pharmacokinetic-pharmacodynamic (PBPK-PD) model of VX. In: Worek F, Jenner J, Thiermann H (eds), Chemical Warfare Toxicology: Volume 1: Fundamental Aspects, pp. 213–263. Royal Society of Chemistry.
Publication: Book Chapters
Glynn ME, Adams RE, Beckett EM, Scott PK, Pierce JS, Finley BL . Human equivalent concentrations for diacetyl based on minimal bronchiolar respiratory effects observed in animals: A refined analysis using current toxicology data and dosimetry models. Abstract #1300. Poster presentation at Society of Toxicology 55th Annual Meeting, New Orleans, LA, 2016.
Publication: Abstracts and Presentations
2015 (5 POSTS)
Wheeler MW, Park R, Bailer A, Whittaker C. 2015. Historical context and recent advances in exposure-response estimation for deriving occupational exposure limits. J Occup Environ Hyg 12(sup1):S7-S17; doi: 10.1080/15459624.2015.1076934 . PMCID: PMC4685605.
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Publication: Manuscripts
Kirman CR, Proctor DM , Suh M , Hays S. Reduction of hexavalent chromium by gastric fluids from fed and fasted individuals with applications to toxicokinetic modeling. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.
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Publication: Abstracts and Presentations
Thompson CM , Suh M , Hixon G, Bichteler A. Comparison of smoothing spline regression and conventional modeling approaches for quantitative risk sssessments of human dioxin exposure. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.
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Publication: Abstracts and Presentations
Reddick H ., Schaefer, C. Using geographic information systems to model paths from remote villages to the nearest Bolivian health clinics. Texas Public Health Association, Austin, TX, 2015.
Publication: Abstracts and Presentations
Cowan DM, Maskrey JR, Fung E, Woods T, Stabryla L, Scott PK, Finley BL . Evaluation of empirically-based PBPK modeling approaches for modeling ante- and post mortem ethanol concentrations in biological matrices. Poster presentation Society of Toxicology 54th Annual Meeting, San Diego, CA, 2015.
Publication: Abstracts and Presentations
2014 (4 POSTS)
Kirman CR, Proctor D, Suh M, Thompson CM , Harris MA, Haws LC , Hays SM. Variation analysis of PBPK model parameters for describing the delivery of Cr(VI) to the small intestines of humans. Presented at Society of Toxicology 53rd Annual Meeting, Phoenix, AZ, March 2014.
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