Thompson CT , Suh M , Chappell G, Borghoff S , Ellis-Hutchings, R, Wiench, K, Finch, L, Proctor, DM . 2018. Assessment of the mode of action underlying development of forestomach tumors in rodents following oral exposure to ethyl acrylate and relevance to humans. Regul Toxicol Pharmacol 96:178–189 doi: 10.1016/j.yrtph.2018.05.006.
Publication: Manuscripts
/ Topics: PFAS , Toxicology
Suh M , Proctor DM , Chappell G, Rager JE, Thompson CM , Borghoff S , Finch L, Ellis-Hutchings R, Wiench K. 2018. A review of the genotoxic, mutagenic, and carcinogenic potentials of several lower acrylates. Toxicology 402-403:50-67, doi: 10.1016/j.tox.2018.04.006.
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Publication: Manuscripts
/ Topics: Toxicology
Proctor DM , Suh M , Chappell G, Borghoff SJ , Thompson CM , Wiench K, Finch L, Ellis-Hutchings R. 2018. An adverse outcome pathway (AOP) for forestomach tumors induced by non-genotoxic initiating events. Regul Toxicol Pharmacol , 96:30-40, doi: 10.1016/j.yrtph.2018.04.016.
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Publication: Manuscripts
/ Topics: Toxicology
Proctor DM. Hexavalent chromium in drinking water: When is the science sufficient to deviate from defaults? Invited Speaker, Genetic and Environmental Toxicology Association (GETA). Thresholds in Toxicology and Risk Assessment Fall Symposium. Oakland, CA, November 14, 2018.
Publication: Abstracts and Presentations
/ Topics: Hexavalent Chromium
Sheridan ER, Jackson M, Paleja A, Martini C, Rashid A, Lea I , Fostel J. Improved searching in the Chemical Effects in Biological Systems (CEBS) database leads to greater utility of NTP data. Presented at the 57th Annual Meeting of Society of Toxicology, San Antonio, TX, March 2018. Abstract 2525-P887.
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Publication: Abstracts and Presentations
/ Topics: Toxicology
Lea IA , Borghoff S, Travlos GS. 2018. Electrolytes, blood gases and acid-base balance. In: Kurtz DM, Travlos GS (eds): The Clinical Chemistry of Laboratory Animals (3rd edition). CRC Press, Boca Raton, FL (https://doi.org/10.1201/9781315155807 ).
Publication: Book Chapters
/ Topics: Toxicology
Shay Hynds EC, Ierardi AM, Burns AM, Finley BL . Derivation of a chronic oral RfD for antimony. Poster presentation at Society of Toxicology 57th Annual Meeting, San Antonio, TX, 2018.
Publication: Abstracts and Presentations
/ Topics: Metals , Toxicology
Kovochich M, Fung D, Unice KM, Mahoney SL, Paustenbach DJ, Finley BL . Understanding divergent outcomes in MoM-THA patient populations with well-fixed components: A critical appraisal of patient management protocols and revision trends (2000-2017). Poster presentation at Society of Toxicology 57th Annual Meeting, San Antonio, TX, 2018.
Publication: Abstracts and Presentations
/ Topics: Metals , Toxicology
Kovochich M, Fung ES, Mahoney SL, Unice KM, Fung D, Paustenbach DJ, Finley BL . Characterizing cytotoxic and inflammatory responses to metal-on-metal wear debris from normal versus edge-loading conditions. Poster presentation at Society of Toxicology 57th Annual Meeting, San Antonio, TX, 2018.
Publication: Abstracts and Presentations
/ Topics: Metals , Toxicology
Burns AM, Benson SM, Best E, Hollins DM, Finley BL . An ecological epidemiology investigation of talc consumption in the US and trends in female cancer rates. Poster presentation at Society of Toxicology 57th Annual Meeting, San Antonio, TX, 2018.
Publication: Abstracts and Presentations
/ Topics: Cancer , Epidemiology , talc
Brorby GP . 2018. The ongoing controversy surrounding the effects of short-term exposure to trichloroethene. Presented at the Association for Environmental Health and Sciences Foundation Annual International Conference, March 19–22, San Diego, CA.
Publication: Abstracts and Presentations
/ Topics: Toxicology
Thompson CM , Kirman CR, Hays SM, Suh M , Harvey SE , Proctor DM , Rager JE, Haws LC , Harris MA . 2018. Integration of mechanistic and pharmacokinetic information to derive oral reference dose and margin-of-exposure values for hexavalent chromium. J Appl Toxicol 38:351–365. doi: 10.1002/jat.3545.
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Publication: Manuscripts
/ Topics: Cr(VI) MOA Study , Hexavalent Chromium
Pangburn HA, Jarvis JP, Covington TR , Ott DK, Gearhart JM. The impact of genetics on the pharmacokinetics of chemicals in a U.S. Air Force population. Poster presented at the Society of Toxicology Annual Meeting, San Antonio, TX, March 2018.
Publication: Abstracts and Presentations
/ Topics: Toxicology
Gearhart JM, Pitts E, Covington TR , Grabinski CM, Yamamoto DP, McKenzie-Smith D, Ott DK, Pangburn HA. Physiological simulation of thermal and chemical stressors in a United States Air Force population. Presentation at the Society of Toxicology Annual Meeting, San Antonio, TX, March 2018.
Publication: Abstracts and Presentations
/ Topics: Toxicology
Covington TR , Ott DK, Gearhart JM, Pangburn HA. Development of a physiologically-based pharmacokinetic model for the virtual high-performance aircraft pilot. Poster presented at the Society of Toxicology Annual Meeting, San Antonio, TX, March 2018.
Publication: Abstracts and Presentations
/ Topics: Toxicology
Pecquet AM, Martinez JM, Vincent M , Erraguntla N, Dourson M. 2018. Derivation of a no-significant-risk-level for tetrabromobisphenol A based on a threshold non-mutagenic cancer mode of action. J Appl Toxicol 38(6):862–878, doi: 10.1002/jat.3594.
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Publication: Manuscripts
/ Topics: Toxicology
Haber LT, Dourson ML, Allen BC, Hertzberg RC, Parker A, Vincent MJ , et al. 2018. Benchmark dose (BMD) modeling: Current practice, issues, and challenges. Crit Rev Toxicol 48(5):387–415, doi: 10.1080/10408444.2018.1430121.
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Publication: Manuscripts
/ Topics: Toxicology
Caballero-Gallardo K, Wirbisky-Hershberger S , Olivero-Verbel J, de la Rosa J, Freeman JL. 2018. Embryonic exposure to an aqueous coal dust extract results in gene expression alterations associated with development and function of connective tissue and the hematological system, immunological and inflammatory disease and cancer in zebrafish. Metallomics 10(3):463–473
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Publication: Manuscripts
/ Topics: Environmental Science
Choksi N , Daniel A, Lebrun S, Nguyen M, DeGeorge G, Willoughby JA, et al. Performance of the OptiSafe ocular irritation assay in a three-laboratory validation study. Poster presented at Society of Toxicology Annual Meeting, San Antonio, TX, March 2018.
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