Pangburn HA, Jarvis JP, Covington TR , Ott DK, Gearhart JM. The impact of genetics on the pharmacokinetics of chemicals in a U.S. Air Force population. Poster presented at the Society of Toxicology Annual Meeting, San Antonio, TX, March 2018.
Publication: Abstracts and Presentations
/ Topics: pharmacokinetics
Gearhart JM, Pitts E, Covington TR , Grabinski CM, Yamamoto DP, McKenzie-Smith D, Ott DK, Pangburn HA. Physiological simulation of thermal and chemical stressors in a United States Air Force population. Presentation at the Society of Toxicology Annual Meeting, San Antonio, TX, March 2018.
Publication: Abstracts and Presentations
/ Topics: community health
Covington TR , Ott DK, Gearhart JM, Pangburn HA. Development of a physiologically-based pharmacokinetic model for the virtual high-performance aircraft pilot. Poster presented at Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.
Publication: Abstracts and Presentations
/ Topics: modeling , pharmacokinetics
Fisk L, Greene N , Naven R. 2018. Physicochemical properties and structural alerts. In: Chen M, Will Y (eds), Drug-Induced Liver Toxicity, Humana: New York, pp. 61-76; doi: 10.1007/978-1-4939-7677-5_4 .
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Publication: Book Chapters
/ Topics: drug development , pharmacokinetics
Pecquet AM, Martinez JM, Vincent M , Erraguntla N, Dourson M. 2018. Derivation of a no-significant-risk-level for tetrabromobisphenol A based on a threshold non-mutagenic cancer mode of action. J Appl Toxicol 38(6):862–878; doi: 10.1002/jat.3594 .
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Publication: Manuscripts
/ Topics: mode of action
Haber LT, Dourson ML, Allen BC, Hertzberg RC, Parker A, Vincent MJ , et al. 2018. Benchmark dose (BMD) modeling: Current practice, issues, and challenges. Crit Rev Toxicol 48(5):387–415; doi: 10.1080/10408444.2018.1430121 .
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Publication: Manuscripts
/ Topics: benchmark dose estimation (BMD) , modeling
Czerkies L, Kineman B, Cohen S, Reichert H , Carvalho R. A pooled analysis of growth and tolerance of infants exclusively fed a partially hydrolyzed whey or intact protein-based infant formulas. Presented at the 5th International Conference on Nutrition and Growth, Paris, France, March 2018.
Publication: Abstracts and Presentations
/ Topics: Epidemiology , Food science , nutrition
Wikoff D (contributing author), EFSA (European Food Safety Authority), EBTC (Evidence-Based Toxicology Collaboration). 2018. EFSA Scientific Colloquium 23. Evidence integration in risk assessment: The science of combining apples and oranges. EFSA Supporting Publication 2018:15(3):1396; doi: 10.2903/sp.efsa.2018.EN-1396 .
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Publication: Manuscripts
/ Topics: risk assessment
Sheridan ER, Jackson M, Paleja A, Martini C, Rashid A, Lea I , Fostel J. Improved searching in the Chemical Effects in Biological Systems (CEBS) database leads to greater utility of NTP data. Abstract 2525-P887, Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.
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Publication: Abstracts and Presentations
/ Topics: computational toxicology
Heintz MM , Kumar R, Baldwin WS. The role of Cyp2b in the metabolism of unsaturated fatty acids. Abstract #1291, Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.
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Publication: Abstracts and Presentations
/ Topics: metabolites
McRee R, Heintz MM , Baldwin WS. Inhibition of CYP2B6 does not necessarily alter toxicity except in the case of chemicals with known active metabolites. Abstract #1292, Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.
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Publication: Abstracts and Presentations
/ Topics: metabolites
Bare JL , Abramson MM, Maskrey JR, Manning CM, Keenan JJ. 2018. Proposition 65 risk assessment model framework for chemically-complex consumer products. Abstract #3525, Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.
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Publication: Abstracts and Presentations
/ Topics: consumer products
Klaren WD , Grimm FA, Shen H, Rusyn I. In vitro approaches to grouping of complex substances and UVCBs: A case study of olefin streams. Society of Toxicology 57th Annual Meeting, San Antonio, TX, 2018.
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Publication: Abstracts and Presentations
/ Topics: regulatory toxicology
Caballero-Gallardo K, Wirbisky-Hershberger S , Olivero-Verbel J, de la Rosa J, Freeman JL. 2018. Embryonic exposure to an aqueous coal dust extract results in gene expression alterations associated with development and function of connective tissue and the hematological system, immunological and inflammatory disease and cancer in zebrafish. Metallomics 10(3):463–473
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Publication: Manuscripts
/ Topics: Environmental Science
Choksi N , Daniel A, Lebrun S, Nguyen M, DeGeorge G, Willoughby JA, et al. Performance of the OptiSafe ocular irritation assay in a three-laboratory validation study. Poster presented at Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.
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Publication: Abstracts and Presentations
/ Topics: NAMs
Bell SM, Chang X, Wambaugh JF, Allen DG, Bartels M, Brouwer … Choksi N , et al. 2018. In vitro to in vivo extrapolation for high throughput prioritization and decision making. Toxicol In Vitro 47:213–227; doi: 10.1016/j.tiv.2017.11.016 .
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Publication: Manuscripts
/ Topics: chemical safety assessment
Verougstraete V, Henderson R , Mackie C, Newson T, Oller A. 2018. Human health (toxicity) assessment of complex inorganic materials. In: Verougstraete V (ed), Risk Management of Complex Inorganic Materials. Elsevier Inc. ISBN 978-0-12-811063-8 .
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Publication: Book Chapters
/ Topics: Metals
Buerger AN , Martyniuk CJ, Bisesi JH. Phthalate disruption of the gastrointestinal microbiome as a potential obesogenic mechanism: A multigenerational study using Danio rerio. Society of Toxicology 57th Annual Meeting, San Antonio, TX, 2018.
Publication: Abstracts and Presentations
/ Topics: phthalates
Buerger AN , Dillon DT, Martyniuk CJ, Bisesi JH. Host-microbiome alterations in fatty acid metabolism in Danio rerio following dietary phthalate exposure. Society of Environmental Toxicology and Chemistry North America Meeting, 2018.
Publication: Abstracts and Presentations
/ Topics: Exposure Assessment , Food science , phthalates
Branch F, Pfahles-Hutchens A, Brown L, Chiger A, Rajan P, Hubbard H, Melia J, Riley K. Data quality evaluation for epidemiologic studies under amended TSCA. Poster presented at the International Society for Environmental Epidemiology/International Society for Environmental Exposure, Ottawa, CA, 2018.