Covington TR , Borghoff SJ , Bacigalupi L, O’Neal S, Cook B, Nelms M, et al. Prediction of chemical suitability for screening in a high-throughput assay platform using an in silico mass balance model. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.
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Publication: Abstracts and Presentations
/ Topics: modeling
Lea IA , Borghoff SJ, Chew R, Bell S, Edwards S, Vasko J, et al. Leveraging computational tools for enhanced human-in-the-loop systematic literature reviews. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.
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Publication: Abstracts and Presentations
/ Topics: Systematic Review
Holt JR, Chew RF, Bunnage E, Lea I, Borghoff SJ, Sayer R, et al. Categorizing articles for environmental health systematic evidence mapping: A zero-shot machine learning approach using large language models. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.
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Publication: Abstracts and Presentations
/ Topics: Health Economics and Outcomes Research (HEOR) , Systematic Review
Hampton LT, Kennedy SB , Barrick A, Wyler DB, Almroth BC, Coffin S, et al. The toxicity of microplastics explorer 2.0: Are we moving the needle forward on microplastics toxicity research? Abstract 7.03.T-05, Society of Environmental Toxicology and Chemistry 45th Annual Meeting, Fort Worth, TX, October 2024.
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Publication: Abstracts and Presentations
/ Topics: microplastics
Lane R, Gill S, Miller EL, Kennedy S , Shankar P, Williams T, et al. Rolling along: State of the science for tire related chemicals 6PPD and 6PPD-quinone. Abstract 4.22.P-Mo-115, Society of Environmental Toxicology and Chemistry 45th Annual Meeting, Fort Worth, TX, October 2024.
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Publication: Abstracts and Presentations
/ Topics: tire particles (TRWP)
Kennedy SB , Doyle D, Coffin S, Mair MM, Cowger W, Barrick A, et al. Trends in quality and risk assessment applicability of microplastic ecotoxicity studies. Abstract 7.03.P-Th-081, Society of Environmental Toxicology and Chemistry 45th Annual Meeting, Fort Worth, TX, October 2024.
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Publication: Abstracts and Presentations
/ Topics: ecotoxicology , Environmental Science
Feifarek D, Kennedy S, Panko J. Mechanistic evaluation of 6PPD-quinone toxicity in fish. Abstract 4.22.B.T-03, Society of Environmental Toxicology and Chemistry 45th Annual Meeting, Fort Worth, TX, October 2024.
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Publication: Abstracts and Presentations
/ Topics: ecotoxicology
Reátegui-Zirena EG, Lange SS, Jenkins A, Heintz MM, Franke K, Perry CS, Thompson C, et al. Acute health-based screening level derivation for cyanotoxins (microcystin, cylindrospermopsin and anatoxins). Abstract 7.05P-Th-197, Society of Environmental Toxicology and Chemistry, 45th Annual Meeting, Fort Worth, TX, October 2024.
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Publication: Abstracts and Presentations
/ Topics: ecotoxicology , water
Pang F, Dean R, Jensen I , Bean K, Fields C, Miller B. The 18-effectiveness of atidarsagene autotemcel (ARSA-CEL) for the treatment of metachromatic leukodystrophy (MLD) in Spain, ISPOR Europe 2024, November 2024.
Publication: Abstracts and Presentations
/ Topics: Health Economics and Outcomes Research (HEOR) , Metachromatic leukodystrophy (MLD)
Bare J , Kennedy SB , Feifarek D, Panko J . Quality and reliability evaluation of 6PPD-quinone surface water occurrence data and considerations for use in risk assessment. Abstract 4.22.P-Mo-119, Society of Environmental Toxicology and Chemistry 45th Annual Meeting, Fort Worth, TX, October 2024.
Publication: Abstracts and Presentations
/ Topics: risk assessment , water
Madl AK, Donnell MT, Covell LT . 2024. Synthetic vitreous fibers (SVFs): Adverse outcome pathways (AOPs) and considerations for next generation new approach methods (NAMs). Crit Rev Toxicol 54(10:754-804; doi: 10.1080/10408444.2024.2390020 . PMID: 39287182.
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Publication: Manuscripts
/ Topics: Cancer
O’Brien J, Mitchell C, Auerbach S, Doonan L, Ewald J, Everett L, Faranda A, Johnson K, Reardon A, Rooney J., Wheeler MW , et al. 2024. Bioinformatic workflows for deriving transcriptomic points of departure: Current status, data gaps, and research priorities. Toxicol Sci 203(2):147-159; doi: 10.1093/toxsci/kfae145 . PMCID: PMC11775421.
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Publication: Manuscripts
/ Topics: transcriptomics
Banerjee A, Kar S, Roy K, Patlewicz G , Charest N, Benfenati E, Cronin MTD. 2024. Molecular similarity in chemical informatics and predictive toxicity modeling: From quantitative read-across (q-RA) to quantitative read-across structure-activity relationship (q-RASAR) with the application of machine learning. Crit Rev Toxicol 54(9):659-684; doi: 10.1080/10408444.2024.2386260 . PMID: 39225123.
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Publication: Manuscripts
/ Topics: modeling
Farris DP, Lebo RA, Price C. 2024. Designing a framework for curriculum building in systematic review competencies for librarians: A case report. J Med Libr Assoc 4:357–363; doi: 10.5195/jmla.2024.1930 .
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Publication: Manuscripts
/ Topics: Systematic Review
Hagan B, Patlewicz G , Shah I. Metabolic similarity in read-across prediction: A case study using graph convolutional networks to predict genotoxicity outcomes from metabolic networks. Abstract 62, American Society for Cellular and Computation Toxicology 13th Annual Meeting, Research Triangle Park, NC, October 2024.
Publication: Abstracts and Presentations
/ Topics: computational toxicology , read-across
Leary AJ, Patlewicz G , Shah I. An exploration of the use of hybrid fingerprints in generalized read-across and their impact on predictive performance for selected in vivo toxicity outcomes. Abstract 42, American Society for Cellular and Computation Toxicology 13th Annual Meeting, Research Triangle Park, NC, October 2024.
Publication: Abstracts and Presentations
/ Topics: computational toxicology , read-across
Rogers JD, Patlewicz G , Baker E, Bettmann A, Clippinger A, Paul Friedman K. High-throughput safety pharmacology screening to better understand data-poor chemicals. Abstract 57, American Society for Cellular and Computation Toxicology 13th Annual Meeting, Research Triangle Park, NC, October 2024.
Publication: Abstracts and Presentations
/ Topics: pharmacology
Seo S, Healey BE, McLin R, Sacks NC , Benson CJ, Citrome L. 2024. Impact of demographics and insurance coverage on schizophrenia treatment and healthcare resource utilization within an integrated healthcare system. Neuropsychiatr Dis Treat 20(Sept 26):1837–1848; doi: 10.2147/NDT.S473492 . PMID: 39351585.
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