2022 (96 POSTS)
Patlewicz G , Nelms MN, Rua D. 2022. Evaluating the utility of the Threshold of Toxicological Concern (TTC) and its exclusions in the biocompatibility assessment of extractable chemical substances from medical devices. Comput Toxicol 24(Nov):100246; doi: 10.1016/j.comtox.2022.100246 . PMID: 36405647.
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Topics: computational toxicology
Cronin MTD, Bauer FJ, Bonnell M, Campos B, Ebbrell DJ, Firman JW, Gutsell S, Hodges G, Patlewicz G , et al. 2022. A scheme to evaluate structural alerts to predict toxicity–Assessing confidence by characterizing uncertainties. Regul Toxicol Pharmacol 135(Nov):105249; doi: 10.1016/j.yrtph.2022.105249 . PMID: 36041585.
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Topics: NAMs
Woo K, Fuld R, Grandinetti A, Lawson J, Litchfield T, Ohan M, Peipert JD, Rivara MB, Nordyke RJ . 2022. Patient-reported outcomes in hemodialysis vascular access: A call to action. J Vasc Access 23(6):973-980; doi: 10.1177/11297298211018295 . PMID: 34032166.
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Topics: Epidemiology
Patlewicz G , Richard AM, Williams AJ, Judson RS, Thomas RS. 2022. Towards reproducible structure-based chemical categories for PFAS to inform and evaluate toxicity and toxicokinetic testing. Comput Toxicol 24(Nov):100250; doi: 10.1016/j.comtox.2022.100250 . PMID: 36969381.
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Topics: NAMs , PFAS
Cohen SS, Bylsma LC, Movva N , Alexander DD. 2022. Theoretical attributable risk analysis and Disability Adjusted Life Years (DALYs) based on increased dairy consumption. BMC Public Health 22(1):1625; doi: 10.1186/s12889-022-14042-7 . PMID: 36030208.
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Topics: Food science , risk analysis
Heintz MM , Chappell GA, Thompson CM , Haws LC . 2022. Evaluation of transcriptomic responses in livers of mice exposed to the short-chain PFAS compound HFPO-DA. Front Toxicol 4(Jun 27):937168; doi: 10.3389/ftox.2022.937168 . PMID: 35832492.
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Topics: PFAS , transcriptomics
Gloekler LE, de Gandiaga EJ, Binczewski NR, Steimel KG, Massarsky A, Kozal J, Vincent M , et al. 2022. Evaluation of the safety and efficacy of hand sanitizer products marketed to children available during the COVID-19 pandemic. Int J Env Res Pub Health 19(21):14424; doi: 10.3390/ijerph19211442 . PMID: 36361303.
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Topics: consumer products , COVID-19
Goyak KO, Sarang SS, Franzen A , Borghoff SJ , Ryman-Rasumssen JP. 2022. Adverse outcome pathway (AOP): α2u-globulin nephropathy and kidney tumors in male rats. Crit Rev Toxicol 52(5):345-357; doi: 10.1080/10408444.2022.2082269 . PMID: 35862579.
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Topics: Adverse outcome pathways (AOPs)
Foster MJ, Patlewicz G , Shah I, Haggard DE, Judson RS, Paul Friedman K. 2022. Evaluating structure-based activity in a high throughput assay for steroid biosynthesis. Comput Toxicol 24(Nov):100245; doi: 10.1016/j.comtox.2022.100245 . PMID: 37841081.
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Topics: NAMs
Frankenfeld CL , Maskarinec G, Franke AA. 2022. Metabolomics profiles of premenopausal women are different based on O-desmethylangolensin metabotype. Brit J Nutr 128(8):1490–1498; doi: 10.1017/S0007114521004463 . PMID: 34763731.
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Topics: metabolites
Knotts T, Mease K , Sangameswaran L, Felx M, Kramer S, Donovan J. 2022. Pharmacokinetics and local tissue response to local instillation of vocacapsaicin, a novel capsaicin prodrug, in rat and rabbit osteotomy models. J Orthop Res 40(10):2281-2293; doi: 10.1002/jor.25271 . PMID: 35128722.
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Topics: drug development , pharmacokinetics
Schaefer HR , Flannery BM, Crosby L, Jones-Dominic OE, Punzalan C, Middleton K. 2022. A systematic review of adverse health effects associated with oral cadmium exposure. Regul Toxicol Pharmacol 134(Oct):105243; doi: 10.1016/j.yrtph.2022.105243 . PMID: 35981600.
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Topics: cadmium , Exposure Assessment , Systematic Review
Nicolas CI, Linakis MW, Minto MS, Mansouri K, Clewell RA, Yoon M, Wambaugh JF, Patlewicz G , et al. 2022. Estimating provisional margins of exposure for data poor chemicals using high throughput computational methods. Front Pharmacol 13(Oct 7):980747; doi: 10.3389/fphar.2022.980747 . PMID: 36278238.
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Topics: computational toxicology
Gupta N, Patel HD, Taylor J, Borin JF, Jacobsohn K,…, Price C , et al. 2022. Systematic review of the impact of a plant-based diet on prostate cancer incidence and outcomes. Prostate Cancer Prostatic Dis 25(3):444–452; doi: 10.1038/s41391-022-00553-2 . PMID: 35790788.
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Topics: Cancer , Systematic Review
Moran KR, Wheeler MW . 2022. Fast increased fidelity samplers for approximate Bayesian Gaussian process regression. J Roy Stat Soc B 84(4):1198-228; doi: 10.1111/rssb.12494 . PMID: 36570797.
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Topics: Bayesian modeling , modeling
Schenfeld J, Gong T, Henry D, Kelsh M , Gawade P, Peng Y, Bradbury BD, Li S. 2022. Patterns of primary prophylactic granulocyte colony-stimulating factor use in older Medicare patients with cancer receiving myelosuppressive chemotherapy. Support Care Cancer 30(7):6327–6338; doi: 10.1007/s00520-022-06967-x . PMID: 35482126.
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Topics: Cancer , Epidemiology
Gillezeau C, Movva N , van Gerwen M, Rabon-Stith K, Shire N, Brohawn PZ, Taioli E, Fryzek J. 2022. Interferon gamma expression and mortality in unselected cohorts of urothelial bladder cancer patients. PLoS One 17(8):e0271339; doi: 10.1371/journal.pone.0271339 . PMID: 36040901.
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Topics: Cancer , Epidemiology
Pouillot R, Farakos SS, Spungen J, Schaefer HR , Flannery BM, Van Doren JM. 2022. Cadmium physiologically based pharmacokinetic (PBPK) models for forward and reverse dosimetry: Review, evaluation, and adaptation to the U.S. population. Toxicol Lett 367(Aug):67-75; doi: 10.1016/j.toxlet.2022.07.812 . PMID: 35901988. Corrigendum: Toxicol Lett 2023 377(March):14-15; doi: 10.1016/j.toxlet.2023.01.011 .
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Topics: biomarkers , cadmium , PBPK/PBDE
Reichert H , Suh M , Jiang X , Movva N , Bylsma LC , Fryzek JP, Nelson CB. 2022. Mortality associated with respiratory syncytial virus, bronchiolitis, and influenza among infants in the United States: A birth cohort study from 1998 to 2018. J Infect Dis 226(Suppl 2):S246–S254; doi: 10.1093/infdis/jiac127 . PMID: 35968877.
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Topics: Epidemiology
Bylsma LC, Suh M, Movva N, Fryzek JP, Nelson CB. 2022. Mortality among United States infants and children under 5 years of age with respiratory syncytial virus and bronchiolitis: A systematic literature review. J Infect Dis 226(Suppl 2):S267–S281; doi: 10.1093/infdis/jiac226 . PMID: 35968871.
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