2020 (86 POSTS)
Adamovsky O, Buerger AN , Vespalcova H, Sohag S, Hanlon A, Ginn P, et al. 2020. Evaluation of microbiome-host relationships in the zebrafish gastrointestinal system reveals adaptive immunity is a target of bis (2-ethylhexyl) phthalate (DEHP) exposure. Environ Sci Technol 54(9):5719–5728 .
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Topics: Toxicology
Howard AS, Choksi NY . 2020. Evaluation of two in silico programs for predicting mutagenicity and carcinogenicity potential for 4-methylimidazole (4-MeI) and known metabolites. Toxicol Mech Method 30:246–256; doi: 10.1080/15376516.2019.1709237 .
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Topics: carcinogens , Toxicology
Choksi N , Lebrun S, Nguyen M, Daniel A, DeGeorge G, Willoughby J, et al. 2020. Validation of the OptiSafe Eye Irritation Test. Cutan Ocul Toxicol 39(3):180–192; doi: 10.1080/15569527.2020.1787431 .
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Topics: Toxicology
Gadagbui B, Moore J, Parker A, McCready D, Monnot AD, Garnick L, Vincent M , et al. 2020. Derivation of cancer no significant risk levels and screening safety assessment for 2-nitropropane in spray products. J Appl Tox 40(5):691–705, doi: 10.1002/jat.3937.
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Topics: Toxicology
Bogdanfy MS, Lesnick J, Mangipudy R, Sistare FD, Colman K, Garcia-Tapla D, Monticello T , Blanset D. 2020. Tg.rasH2 mouse model for assessing carcinogenic potential of pharmaceuticals: Industry survey of current practices. Int J Toxicol 39(3):198-206; doi: 10.1177/1091581820919896 .
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Topics: carcinogens , pharmaceuticals
Shukla A, Harper M, Pedersen E, Goman, A, Suen JJ, Price C , et al. 2020. Hearing loss, loneliness, and social isolation: A systematic review. Otolaryngol—Head Neck Surg 162(5):622–633; https://doi.org/10.1177/0194599820910377 .
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Topics: hearing loss , Systematic Review
Wikoff DS , Bennett DC, Brorby GP , Franke KS . 2020. Evaluation of potential human health risk associated with consumption of edible products from livestock fed ration supplemented with Red Lake Diatomaceous Earth. Food Addit Contam A 37(5):804-814; doi: 10.1080/19440049.2020.1727963 . PMID: 32134694.
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Topics: Food science , risk assessment , Toxicology
Thompson CM , Gentry R, Fitch S , Lu K, Clewell HJ. 2020. An updated mode of action and human relevance framework evaluation for formaldehyde-related nasal tumors. Crit Rev Toxicol 50(10):919–952; doi: 10.1080/10408444.2020.1854679 .
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Topics: formaldehyde , Toxicology
Gentry R, Thompson CM , Franzen A , Salley J, Albertini R, Lu K, Greene T. 2020. Using mechanistic information to support evidence integration and synthesis: A case study with inhaled formaldehyde and leukemia. Crit Rev Toxicol 50(10):885–918, DOI: 10.1080/10408444.2020.1854678.
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Topics: Toxicology
Walz E, Middleton J, Sampedro F , VanderWaal K, Malladi S, Goldsmith T. 2020. Modeling the transmission of foot and mouth disease to inform transportation of infected carcasses to a disposal site during an outbreak event. Front Vet Sci 6:501; doi: 10.3389/fvets.2019.00501 .
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Topics: modeling , Toxicology
Brusa V, Costa M, Padola NL, Etcheverria A, Sampedro F , Fernandez PS, Leotta GA, Signorini ML. 2020. Quantitative risk assessment of haemolytic uremic syndrome associated with beef consumption in Argentina. PLOS ONE 15(11): e0242317.
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Topics: Food science
Brown L, Lynch M, Belova A, Klein R, Chiger A. 2020. Developing a health impact model for adult lead exposure and cardiovascular disease mortality. Environ Health Persp 128:9, https://doi.org/10.1289/EHP6552.
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Topics: Toxicology
Baudy AR, Otieno MA, Hewitt P, Gan J, Roth A, Keller D , Sura R, Van Vleet TR, Proctor WR. 2020. Liver microphysiological systems development guidelines for safety risk assessment in the pharmaceutical industry. Lab Chip 20(2):215–225, doi: 10.1039/c9lc00768g.
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Topics: Toxicology
Roth SE, Avigan MI, Bourdet D, Brott D, Church R, Dash A, Keller D , Sherratt P, Watkins PB, Westcott-Baker L, Lentini S, Merz M, Ramaiah L, Ramaiah SK, Stanley AM, Marcinak J. 2020. Next-generation DILI biomarkers: Prioritization of biomarkers for qualification and best practices for biospecimen collection in drug development. Clin Pharmacol Ther 107(2):333–346, doi: 10.1002/cpt.1571 .
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Topics: Toxicology
Phillips JA, Grandhi TSP, Davis M, Gautier, J-C, Hariparsad N, Keller D , Sura R, Van Vleet TR. 2020. A pharmaceutical industry perspective on microphysiological kidney systems for evaluation of safety for new therapies. Lab Chip 20(3):468–476, doi: 10.1039/c9lc00925f.
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Topics: Toxicology
Peters MF, Choy AL, Pin C, Leishman DJ, Moisan A, Ewart L, Guzzie-Peck PJ, Sura R, Keller DA , Scott CW, Kolaja KL. 2020. Developing in vitro assays to transform gastrointestinal safety assessment: Potential for microphysiological systems. Lab Chip 20(7):1177–1190, doi: 10.1039/c9lc01107b.
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Topics: Toxicology
Liu S, Refaei M, Liu S, Decker A, Hinerman JM , Herr AB, Howell M, Musier-Forsyth K, Tsang P. 2020. Hairpin RNA-induced conformational change of a eukaryotic-specific lysyl-tRNA synthetase extension and role of adjacent anticodon-binding domain. J Biol Chem 295(34):12071–12085.
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