2018 (35 POSTS)
Harrill AH, Borghoff S , Zorrilla L, Blystone C, Kissling GE, Malarkey D, Shockley K, Travlos G, DeVito MJ. 2018. NTP Research Report on baseline characteristics of Diversity Outbred (J:DO) mice relevant to toxicology studies. National Toxicology Program Research Report 6, Research Triangle Park, NC.
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Topics: Toxicology
Casey WM, Chang X, Allen DG, Ceger PC, Choksi NY , Hsieh JH, et al. 2018. Evaluation and optimization of pharmacokinetic models for in vitro to in vivo extrapolation of estrogenic activity for environmental chemicals. Environ Health Perspect 126:97001, DOI: 10.1289/EHP1655
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Topics: Toxicology
Wikoff DS, Thompson C , Rager J, Chappell G, Fitch S, Doepker C . 2018. Benefit-risk analysis for foods (BRAFO): Evaluation of exposure to dietary nitrates. Food Chem Toxicol 120:709-723.
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Topics: Toxicology
Roe AL, McMillan DA , Mahony C. 2018. A tiered approach for the evaluation of the safety of botanicals used as dietary supplements: An industry strategy. Clin Pharmacol Therapeut 104(3):446–457.
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Topics: Toxicology
Adamovsky O, Buerger AN , Wormington AM, Ector N, Griffitt RJ, Bisesi JH, et al. 2018. The gut microbiome and aquatic toxicology: An emerging concept for environmental health. Environ Toxicol Chem 37(11):2758–2775 .
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Topics: Toxicology
Moffat I, Martinova N, Seidel C, Thompson CM. 2018. Hexavalent chromium in drinking water. Journal AWWA 110:5.
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Topics: Cr(VI) MOA Study , Hexavalent Chromium
Klaren WD , Rusyn I. 2018. High-content assay multiplexing for muscle toxicity screening in human-induced pluripotent stem cell-derived skeletal myoblasts. Assay Drug Dev Technol 16(6):333–342, PMID: 30070899.
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Topics: Toxicology
Powles MA, Galgoci A, Misura A, Colwell L, Dingley K , Tang W, et al. 2018. In vivo efficacy of relebactam (MK-7655) in combination with imipenem/cilastatin in murine infection models. Antimicrob Agents Chemother 62:e02577–17; doi: 10.1128/AAC.02577-17 . PMID: 29866878.
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Topics: Toxicology
Liu W, Hussain Z, Zang Y, Sweis RF, Romero FA, Finke PE, … Dingley KH , et al. 2018. Optimization of preclinical metabolism for somatostatin receptor subtype 5-selective antagonists. ACS Med Chem Lett (9):1088–1093; doi: 10.1021/acsmedchemlett.8b00306 . PMID: 30429950.
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Topics: Toxicology
Fung ES, Unice KM, Paustenbach DJ, Finley BL , Kovochich M. 2018. Methods for sterilizing clinically relevant wear particles isolated from metal-on-metal hip implants. Sci Rep 8(1):2384.
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Topics: Toxicology
Barlow CA, Marsh GM, Benson S, Finley BL . 2018. The mineralogy and epidemiology of cosmetic talc. Toxicol Appl Pharmacol 361:173.
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Topics: Epidemiology
Kovochich M, Finley BL , Novick R, Monnot AD, Donovan E, Unice KM, Fung ES, Fung D, Paustenbach DJ. 2018. Understanding outcomes and toxicological aspects of second-generation metal-on-metal hip implants: A state-of-the-art review. Crit Rev Toxicol 48(10):839–887.
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Topics: Metals , Toxicology
Sacks NC , Sharma A, Cyr PL, Bertiger G, Dahdal DN, Brogadir S. 2018. Real-world evidence comparison of the efficacy and safety of different bowel preparation agents in a high-risk population. Gastrointest Endosc 87(6) Suppl:AB366.
Topics: Epidemiology
Sacks NC , Sharma A, Cyr PL, Bertiger G, Dahdal DN, Brogadir S. 2018. Real-world comparison of the effectiveness and safety of different bowel preparation agents. Clin Exp Gastroenterol 11:289–299.
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Topics: Epidemiology
Sacks NC , Cyr PL, Louie AC, Liu Ym Chiarella MT, Sharma A, Chung KC. 2018. Burden of acute myeloid leukemia among older, newly diagnosed patients: Retrospective analysis of data from the 2010-2012 Medicare limited data set. Clin Ther 40(5):692–703.e2.
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Topics: Health Economics and Outcomes Research (HEOR)
Wikoff DS , Miller GW. 2018. Systematic reviews in toxicology (Editorial). Toxicol Sci 163(2):335–337.
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Topics: Systematic Review , Toxicology
Ruzin A, Pastula ST , Levin-Sparenberg EM, Jiang X, Fryzek JP, Tovchigrechko A, Lu B, Qi Y, Liu H, Jin H, Yu L, Hackett J, Villafana T, Esser MT. 2018. Characterization of circulating RSV strains among subjects in the OUTSMART-RSV surveillance program during the 2016-17 winter viral season in the United States . PLoS One 13(7):e0200319.
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Topics: Toxicology
Garabrant DH, Pastula ST . 2018. A comparison of asbestos fiber potency and elongate mineral particle (EMP) potency for mesothelioma in humans. Toxicol Appl Pharmacol 361:127–136.
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Topics: Toxicology
Thompson CT , Suh M , Chappell G, Borghoff S , Ellis-Hutchings, R, Wiench, K, Finch, L, Proctor, DM . 2018. Assessment of the mode of action underlying development of forestomach tumors in rodents following oral exposure to ethyl acrylate and relevance to humans. Regul Toxicol Pharmacol 96:178–189 doi: 10.1016/j.yrtph.2018.05.006.
Topics: PFAS , Toxicology
Suh M , Proctor DM , Chappell G, Rager JE, Thompson CM , Borghoff S , Finch L, Ellis-Hutchings R, Wiench K. 2018. A review of the genotoxic, mutagenic, and carcinogenic potentials of several lower acrylates. Toxicology 402-403:50-67, doi: 10.1016/j.tox.2018.04.006.
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