2015 (48 POSTS)
Steinbach T, Gad-McDonald S, Kruhlak N, Powley M, Greene N . 2015. (Q)SAR: A tool for the toxicologist. Int J Toxicol 34(4):352-4; doi: 10.1177/1091581815584914 . PMID: 25979517.
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Topics: computational toxicology
Greene N , Dobo KL, Kenyon MO, Cheung J, Munzner J, Sobol Z, Sluggett G, Zelesky T, et al. 2015. A practical application of two in silico systems for identification of potentially mutagenic impurities. Regul Toxicol Pharmacol 72(2):335-49; doi: 10.1016/j.yrtph.2015.05.008 . PMID: 25980641.
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Topics: computational toxicology , genotoxicity
Wirbisky SE , Weber GJ, Sepúlveda MS, Xiao C, Cannon JR, Freeman JL. 2015. Developmental origins of neurotransmitter and transcriptome alterations in adult female zebrafish exposed to atrazine during embryogenesis. Toxicology 333:156–167.
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Topics: atrazine
Klaren WD , Gadupudi GS, Wels B, Simmons DL, Olivier AK, Ludewig G, Robertson LW. 2015. Progression of micronutrient alteration and hepatotoxicity following acute exposure to PCB126. Toxicol 338(Dec):1–7; doi: 10.1016/j.tox.2015.09.004 . PMID: 26410179.
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Topics: PCBs
Borghoff SJ , Poet TS, Green S, Davis J, Hughes B, Mensing T, Sarang SS, Lynch AM, Hard GC. 2015. Methyl isobutyl ketone exposure-related increases in specific measures of α2u-globulin (α2u) nephropathy in male rats along with in vitro evidence of reversible protein binding. Toxicology 333(July 3):1-13; doi: 10.1016/j.tox.2015.02.003 . PMID: 25797582.
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Topics: Exposure Assessment , mode of action
Gadupudi GS, Klaren WD , Olivier AK, Klingelhutz AJ, Robertson LW. PCB126-induced disruption in gluconeogenesis and fatty acid oxidation precedes fatty liver in male rats. Superfund Annual Meeting, San Juan, Puerto Rico, 2015.
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Topics: PCBs
Gauthier AM, Fung M, Panko J , Kingsbury T, Perez AL, Hitchcock K, Ferracini T, Sahmel J, Banducci A, Jacobsen M, Abelmann A, Shay E. 2015. Chemical assessment state of the science: Evaluation of 32 decision-support tools used to screen and prioritize chemicals. Integr Environ Assess Manag 11(2):242–255; doi: 10.1002/ieam.1605 .
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Topics: chemical safety assessment , risk assessment
Kreider ML, Cyrs WD, Tosiano MA, Panko JM . 2015. Evaluation of quantitative exposure assessment method for nanomaterials in mixed dust environments: Application in tire manufacturing facilities. Ann Occup Hyg 59(9):1122–1134; doi: 10.1093/annhyg/mev052 .
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Topics: Exposure Assessment , nanomaterials , tire particles (TRWP)
Jensen I , Halbert R, Giuseppe R, Naoshy S, Iqbal SU, Zhimin X, McSweeney P. 2015. A hospital budget impact model to evaluate plerixafor in stem cell mobilization: Impact of primary research and direct stakeholder engagement. Eur J Hosp Pharm 22(3):142–149; doi: 10.1136/ejhpharm-2014-000543 .
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Topics: Health Economics and Outcomes Research (HEOR)
Petkov P, Patlewicz G , Schultz TW, Honma M, Todorov M, Kotov S, Dimitrov SD, Donner EM, Mekenyan OM. 2015. A feasibility study: Can information collected to classify for mutagenicity be informative in predicting carcinogenicity? Regul Toxicol Pharmacol 72(1):17-25; doi: 10.1016/j.yrtph.2015.03.003 . PMID: 25792138.
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Topics: Adverse outcome pathways (AOPs) , carcinogens
Patlewicz G , Ball N, Boogaard P, Becker RA, Hubesch B. 2015. Building scientific confidence in the development and evaluation of read-across. Regul Toxicol Pharmacol 72(1):117-133; doi: 10.1016/j.yrtph.2015.03.015 . PMID: 25857293.
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Topics: Adverse outcome pathways (AOPs) , read-across
Liu P, Hu Z, DuBois BG, Moyes CR, Hunter DN, Zhu C, … Dingley KH , et al. 2015. Design of potent and orally active GPR119 agonists for the treatment of type II diabetes. ACS Med Chem Lett 6(8):936–941; doi: 10.1021/acsmedchemlett.5b00207 . PMID: 26288697.
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Topics: diabetes
Tvermoes BE, Paustenbach DJ, Kerger BD, Finley BL , Unice KM. 2015. Review of cobalt toxicokinetics following oral dosing: Implications for health risk assessments and metal-on-metal hip implant patients. Crit Rev Toxicol 45(5):367–387.
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Topics: cobalt , toxicokinetics
Madl AK, Liong M, Kovochich M, Finley BL , Paustenbach DJ, Oberdorster G. 2015. Toxicology of wear particles of cobalt-chromium alloy metal-on-metal hip implants Part I: Physiochemical properties in patient and simulator studies. Nanomed: Nanotechnol Biol Med 11(5):1201–1215; doi: 10.1016/j.nano.2015.02.006 .
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Topics: chromium , cobalt , Metals , nanomaterials
Pierce JS, Abelmann A, Lotter JT, Comerford C, Keeton K, Finley BL . 2015. Characterization of naturally occurring airborne diacetyl concentrations associated with the preparation and consumption of unflavored coffee. Toxicol Rep 2:1200–1208; doi: 10.1016/j.toxrep.2015.08.006 .
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Topics: diacetyl , Exposure Assessment , food additives , Food science
Ruestow PS, Duke TJ, Finley BL , Pierce JS. 2015. Effects of the NFL’s amendments to the Free Kick rule on injuries during the 2010 and 2011 season. J Occupat Environ Hyg 12(12):875–882.
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Topics: Occupational
Sacks NC , Ash AS, Ghosh K, Rosen AK, Wong JB, Cutler DM, Rosen AB. 2015. Recent national trends in acute myocardial infarction hospitalizations in Medicare: Shrinking declines and growing disparities [Letter to the Editor]. Epidemiol 26(4):e46–47; doi: 10.1097/EDE.0000000000000298 .
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