Publications

Frankos VH, Schmitt DF, Haws LC, McEvily AJ, Iyengar R, Miller SA, Munro IC, Clydsdale FM, Forbes AL, and Sauer RM. 1991. Generally recognized as safe (GRAS) evaluation of 4-hexylresorcinol for use as a processing aid for the prevention of melanosis in shrimp. Reg Toxicol Pharmacol. 14:202-212.

Piskorska-Pliszczynska, J, Astroff B, Zacharewski T, Harris MA, Rosengren R, Morrison V, Safe L, and Safe S. 1991. Mechanism of action of 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonists: characterization of 6-[125I]methyl-8-iodo-1,3-dichlorodibenzofuran-Ah receptor complexes. Arch Biochem Biophys 284(1):193-200.

Sipes IG, McMillan DA, Steup DR, Eskelson C. 1991. Synergistic hepatotoxicity in Fischer 344 rats: Effects of trichloroethylene on carbon tetrachloride metabolism and lipid peroxidation. Proc Fourth Int Conf on the Combined Effects of Environmental Factors. Arch Complex Environ Studies, Baltimore, MD.

Steup DR, Wiersma D, McMillan DA, Sipes IG. 1991. Pretreatment with drinking water solutions containing trichloroethylene or chloroform enhances the hepatotoxicity of carbon tetrachloride in Fischer 344 rats. Fund Appl Toxicol 16:798–809.

Safe S, Astroff B, Harris MA, Zacharewski T, Dickerson R, Romkes M, and Biegel L. 1991. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and related compounds as antioestrogens: characterization and mechanism of action. Pharmacol Toxicol. 69:400-409.

Safe S, Harris MA, Biegel L, and Zacharewski T. 1991. Mechanism of Action of TCDD as an antiestrogen in transformed human breast cancer and rodent cell lines. Banbury Report 35: Biological Basis for Risk Assessment of Dioxins and Related Compounds Cold Spring Harbor Laboratory Press. 367-377.

Vater ST, Hollingsworth L, Baldwin DM, Warshawsky D. 1991. Comparative metabolism of 7,12-dimethylbenz[a]anthracene by the perfused liver and liver microsomal preparations from Sprague-Dawley rats. Carcinogenesis 12(12):2379–2382.

Vater ST, Baldwin DM, Warshawsky D. 1991. Hepatic metabolism of 7,12-dimethylbenz(a)anthracene in male, female, and ovariectomized Sprague-Dawley rats. Cancer Res 51(2):492–498.

Lea I, Moore HD, Latchman DS. 1991. Differential expression of the mouse U1a and U1b SnRNA genes is not dependent on sequence differences in the octamer motif. Biochem J 277( Pt 3):719–722.

Zacharewski T, Harris MA, and Safe S. 1991. Evidence for a possible mechanism of action of the 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated decrease of nuclear estrogen receptor levels in wild-type and mutant Hepa 1c1c7 cells. Biochem Pharmacol. 41:1931-1939.

Couture-Haws L, Abbott BD, and Birnbaum LS. 1990. A critical review of the developmental toxicity and teratogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin: recent advances in understanding the mechanism. Teratol. 42:619-627.

Couture, LA, Harris MW, and Birnbaum LS. 1990. Characterization of the peak period of sensitivity for the induction of hydronephrosis in C57BL/6N mice following exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Fundam Appl Toxicol. 15:142-150.

Harris MA, Piskorska-Pliszczynska J, Zacharewski T, and Safe S. 1990. Human breast cancer cell lines as models for investigating the effects of TCDD and related compounds. Chemosphere. 20(7-9):1135-1140.

Harris MA, Zacharewski T, Piskorska-Pliszcyznska J, Rosengren R, and Safe S. 1990. Structure-dependent induction of aryl hydrocarbon hydroxylase activity in C57BL/6 Mice by 2,3,7,8-tetrachlordibenzo-p-dioxin and related congeners: mechanistic studies. Toxicol Appl Pharmacol. 105:243-253.

Harris MA, Zacharewski T, and Safe S. 1990. Effects of 2,3,7,8-tetrachorodibenzo-p-dioxin and related compounds on the occupied nuclear estrogen receptor in MCF-7 human breast cancer cells. Cancer Res. 50:3579-3584.

Randerath K, Putman KL, Randerath E, Harris MA, Zacharewski T, and Safe S. 1990. Effects of 2,3,7,8-TCDD and related compounds on the levels of age-dependent I-spot DNA adducts in the liver of female and male Sprague-Dawley rats. Chemosphere 20(7-9):1049-1052.

Randerath K, Putman KL, Randerath E, Zacharewski T, Harris MA, and Safe S. 1990. Effects on 2,3,7,8-tetrachlorodibenzo-p-dioxin on I-compounds in hepatic DNA of Sprague-Dawley rats: sex specific effects and structure-activity relationships. Toxicol Appl Pharmacol. 103:271-280.

Safe S, Harris MA, Zacharewski T, and Biegel L. 1990. 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) as an antiestrogen in human breast cancer cells: mechanistic studies. Proceedings Dioxin `90, Eco-Informa Press. Bayreuth, Germany, 1:137-140.

Biegel L, Harris MA, Davis D, Rosengren R, Safe L, and Safe S. 1989. 2,2′,4,4′,5,5′-hexachlorobiphenyl as a 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist in C57BL/6J mice. Toxicol Appl Pharmacol. 97:561-571.

Birnbaum LS, Couture LA, and Elwell MR. 1989. Subchronic effects of exposure to Octachlorodibenzo-p-dioxin (OCDD). Chemosphere. 18(1-6):389-390.