Publications

Couture LA, Harris MW, and Birnbaum LS. 1989. Developmental toxicity of 2,3,4,7,8-pentachlorodibenzofuran (4-PeCDF) in the Fischer 344 rat. Fundam Appl Toxicol. 12:358-366.

Harris, MA, Piskorska-Pliszczynska J, Zacharewski T, Romkes M, and Safe S. 1989. Structure-dependent induction of aryl hydrocarbon hydroxylase in human breast cancer cell lines and characterization of the Ah receptor. Cancer Res. 49:4531-4535.

Harris MA, Zacharewski T, Astroff B, Kamps C, and Safe S. 1989. Characterization of 6-methyl-1,3,8-trichlorodibenzofuran (MCDF) as a 2,3,7,8-TCDD antagonist in male rats: induction of monooxygenases. Chemosphere. 19:769-772.

Harris MA, Zacharewski T, Astroff B, and Safe S. 1989. Partial antagonism of 2,3,7,8-tetrachlorodibenzo-p-dioxin mediated induction of aryl hydrocarbon hydroxylase by 6-methyl-1,3,8-trichlorodibenzofuran: mechanistic studies. Mol Pharmacol. 35:729-735.

Rish W, Patterson J, Lutkenhoff S. 1989. Use of health risk estimates in U.S. EPA. USEPA National Center for Environmental Assessment. Proceedings of the 1989 Annual Meeting of the Society for Risk Analysis. San Francisco, California.

Safe S, Mason G, Sawyer T, Zacharewski T, Harris MA, Yao C, Keys B, Farrell K, Holcomb M, Davis D, Safe L, Piskorska-Pliszcyzynska J, Leece B, Denomme M, Hutzinger O, Thoma H, Chittim B, and Madge J. 1989. Development and validation of in vitro induction assays for toxic halogenated aromatic mixtures: a review. Toxicol Ind Health. 5(5):757-775.

Safe S, Zacharewski T, Safe L, Harris MA, Yao C, and Holcomb M. 1989. Validation of the AHH induction bioassay for the determination of 2,3,7,8-TCDD toxic equivalents. Chemosphere. 18(1-6):941-946.

Zacharewski T, Harris MA, and Safe S. 1989. Induction of cytochrome P450-dependent monooxygenase activities in rat hepatoma H-4-IIE cells in culture by 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds: mechanistic studies using radiolabeled congeners. Arch Biochem Biophys. 272(2):344-355.

Zacharewski T, Harris MA, Safe S, Thoma H, Hauschulz G, Knorr E, and Hutzinger O. 1989. Application of the in vitro AHH induction bioassay for determining 2,3,7,8-TCDD equivalents: pyrolyzed flame retardant mixtures. Chemosphere. 18(1-6):383-387.

Birnbaum LS and Couture LA. 1988. Disposition of Octachlorodibenzo-p-dioxin (OCDD) in male rats. Toxicol Appl Pharmacol. 93:22-30.

Couture LA, Elwell MR, and Birnbaum LS. 1988. Dioxin-like effects observed in male rats following exposure to Octachlorodibenzo-p-dioxin (OCDD) during a 13-week study. Toxicol Appl Pharmacol. 93:31-46.

Harris MA, Kamps C, and Safe S. 1988. Role of the 4-5S binding protein in the induction of aryl hydrocarbon hydroxylase in the rat. Carcinogenesis. 9(8):1475-1479.

Rish W. 1988. Review of studies related to uncertainty in risk analysis. ORNL/TM 10776 (with R.J. Marnicio). Report to U.S. Environmental Protection Agency, Office of Radiation Programs, Analysis and Support Division, Oak Ridge National Laboratory.

Rish W. 1988. Approach to uncertainty in risk analysis. ORNL/TM 10746. Report to U.S. Environmental Protection Agency, Office of Radiation Programs, Analysis and Support Division. Oak Ridge National Laboratory.

Zacharewski T, Harris MA, Safe S, Thoma H, and Hutzinger O. 1988. Applications of the in vitro aryl hydrocarbon hydroxylase induction assay for determining “2,3,7,8-tetrachlorodibenzo-p-dioxin equivalents”: pyrolyzed brominated flame retardants. Toxicology. 51:177-189.

Rylander LA, Phelps JS, Gandolfi AJ, Brendel K. 1985. In vitro nephrotoxicity: Response of isolated renal tubules to cadmium chloride and dichlorovinylcysteine. In Vitro Toxicology 1(2):111–127.

Rylander LA, Gandolfi AJ, Brendel K. 1985. Inhibition of organic acid/base transport in isolated rabbit renal tubules by nephrotoxius. In: Alternative Methods in Toxicology series, Volume 3. In Vitro Toxicology 1(2):235–247.

McMillan DA, Schnell RC. 1985. Amelioration of bromobenzene hepatotoxicity in the male rat by zinc. Fund Appl Toxicol 5:297–304.

Hasegawa R, St John MK, Cano M, Issenburg P, Klein DA, Walker BA, Jones JW, Schnell RC, Merrick BA, Davies MH, McMillan DA, Cohen SM. 1984. Bladder freeze ulceration and sodium saccharin feeding in the rat, examination for urinary nitrosamines, mutagens, and bacteria, and effects on hepatic microsomal enzymes. Food Chem Toxicol 22:935–942.

Schnell RC, Bozigian HP, Davies MH, Merrick BA, Park KS, McMillan DA. 1984. Factors influencing circadian rhythms in acetaminophen lethality. Pharmacology 29:149–157.