2025 (102 POSTS)
Muller K, Unice K, Panko J , Ferrari BJD, Breider F, Wagner S. 2025. Risk assessment of tire wear in the environment—A literature review. Environ Sci Process Impacts 27(8):2212-2232; doi: 10.1039/d5em00088b . PMID: 40569214.
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Publication: Manuscripts
/ Topics: ecotoxicology , Environmental Science , leachables , risk assessment , tire particles (TRWP)
Reynolds JI , Johnson BP. 2025. AOP 460: Antagonism of Smoothened receptor leads to orofacial clefting. ALTEX; doi: 10.14573/altex.2407121 . Advance online publication August 11, 2025.
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Publication: Manuscripts
/ Topics: Adverse outcome pathways (AOPs) , NAMs
Proctor D, Jiang X, Reichert H, Thompson C . 2025. Why rat oral cavity tumors should not be the basis of quantitative cancer risk assessment for oral exposure to hexavalent chromium. Toxicol Sci kfaf112; doi: 10.1093/toxsci/kfaf112 . Online ahead of print August 8, 2025. PMID: 40795394.
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Publication: Manuscripts
/ Topics: Cancer , chromium , Exposure Assessment , risk assessment
Moyer HL, Vergara L, Stephan C, Sakolish C, Lin HC, Chiu WA, Villenave R, Hewitt P, et al. 2025. Human small intestinal tissue models to assess barrier permeability: Comparative analysis of caco-2 cells, jejunal and duodenal enteroid-derived cells, and EpiIntestinalTM tissues in membrane-based cultures with and without flow. Bioengineering (Basel). 12(8):809; doi: 10.3390/bioengineering12080809 . PMID: 40868322; PMCID: PMC12384003.
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Publication: Manuscripts
/ Topics: NAMs
Clouser MC, Suh M , Movva N , Hildebrand JS, Pastula ST, Schoehl M, Hindoyan A, Balasubramanian A, et al. 2025. A systematic literature review of MTAP deletions in solid and hematologic cancers. Cancer Treat Res Comm 44:100966; doi: 10.1016/j.ctarc.2025.100966 . PMID: 40729867.
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Publication: Manuscripts
/ Topics: Cancer , Systematic Review
Monticello TM , MacLachlan TK, Funk KA, Rock BM, Bussiere JL, Grieves JL, Schuh JCL, Henry S. 2025. Nonclinical safety assessment: An overview of drug and medical device development. Chapter 1 in: Bouchard PR, Sahota PS, Wallace S, Wojcinski ZW, Schumacher VL (eds), Toxicologic Pathology: Nonclinical Safety Assessment, 3rd edition. Boca Raton: CRC Press-Taylor and Francis Group, pp. 3-51.
Publication: Book Chapters
/ Topics: drug development , nonclinical safety assessment
Patlewicz G , Judson, Paul Friedman K, Wetmore BA, DeVito MJ, Harrill JA, Carstens KE, Houck KA, et al. 2025. Insights derived from testing a library of per- and polyfluoroalkyl substances (PFAS) in a battery of new approach methods (NAMs). J Toxicol Environ Health B online ahead of print July 6; doi: 10.1080/10937404.2025.2521615 . PMID: 40619890.
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Publication: Manuscripts
/ Topics: NAMs , PFAS
Kenyon EM, DeVito MJ, Patlewicz G , Adams LD, Thomas RS, Ambroso JL, Yang X, Blake JC, et al. 2025. Subchronic toxicity of four per- and polyfluoroalkyl substances by oral exposure in Sprague Dawley rats. Toxics 13(7):524; doi: 10.3390/toxics13070524 . PMID: 40710969.
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Publication: Manuscripts
/ Topics: PFAS
Leary A, Shah I, Patlewicz G . 2025. An exploration of the use of hybrid fingerprints in Generalized Read-Across and their impact on predictive performance for selected in vivo toxicity outcomes. Comput Toxicol 34(June):100349; doi: 10.1016/j.comtox.2025.100349 .
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Publication: Manuscripts
/ Topics: NAMs , read-across
Hagan B, Shah I, Patlewicz G . 2025. Can graph similarity metrics be helpful for analogue identification as part of a read-across approach? Comput Toxicol 34(June):100353; doi: 10.1016/j.comtox.2025.100353 .
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Publication: Manuscripts
Muller K, Unice K, Panko J , Wagner S. 2025. Tire emissions during the use phase of tires – Current and future trends. Environ Sci Adv 4(9):1344-1363; doi: 10.1039/d4va00407h .
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Publication: Manuscripts
/ Topics: tire particles (TRWP)
Hughes MF, DeVito MJ, Patlewicz G , Thomas RS, Adams LD, Ambroso JL, Yang X, Upadhyay BG, et al. 2025. Immunotoxicity of four per- and polyfluoroalkyl substances following 28-day oral repeat dosing in rats assessed by the anti-sheep red blood IgM response. Toxics 13(6):490; doi: 10.3390/toxics13060490 . PMID: 40559963.
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Publication: Manuscripts
/ Topics: PFAS
Rogers JM . 2025. Maternally mediated developmental toxicity. In: Comprehensive Toxicology, 4th Edition. Elsevier. In Press (Sept 2025). Available online June 9, 2025 via Reference Module in Biomedical Sciences; doi: 10.1016/B978-0-323-95488-4.00280-1 .
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Publication: Book Chapters
/ Topics: food additives , risk assessment
Brorby G, Franzen A, Thompson C, Wikoff D, Doepker C . 2025. Human health risk assessment of three smoke flavoring primary products. Food Chem Toxicol 202(Aug):115490; doi: 10.1016/j.fct.2025.115490 . PMID: 40320068.
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Publication: Manuscripts
/ Topics: food safety , Food science , genotoxicity , risk assessment , safety assessment
East A, Wheeler M, Kennedy S . Artificial intelligence application to critical appraisal of published literature: A case example using the Criteria for Reporting and Evaluating Ecotoxicity Data (CRED) evaluation method. Poster presentation, Health and Environmental Sciences Institute (HESI) Biannual Meeting, Washington, DC, June 2025.
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Publication: Abstracts and Presentations
/ Topics: ecotoxicology
Hagan B, Groff L, Patlewicz G , Shah. 2025. Toward metabolic similarity in read-across: A case study using graph convolutional networks to predict genotoxicity outcomes. Chem Res Toxicol 38(6):1122-1133; doi: 10.1021/acs.chemrestox.5c00120 . PMID: 40432291.
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Publication: Manuscripts
/ Topics: genotoxicity
Price M, Suh M , Pastula S , Kruchko C, Ostrom Q. Pediatric low-grade glioma (pLGG) incidence in the United States from 2015 through 2019. Abstract LGG-04, Society for NeuroOncology (SNO) Pediatric Neuro-Oncology Conference, San Diego, CA, May 2025.
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Publication: Abstracts and Presentations
/ Topics: Cancer
Thornton Hampton L, Mair MM, Kennedy SB , Wyler DB, Carney Almroth B, Coffin S, Cowger W,…, et al. The Toxicity of Microplastics Explorer (ToMEx) 2.0 database–A unique compilation of microplastics effects measurements for environmental risk assessment. Abstract 1.09.P-Mo-061, Society of Environmental Toxicology and Chemistry 35th Annual Meeting, Vienna, Austria, May 2025.
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Publication: Abstracts and Presentations
/ Topics: microplastics
Kennedy SB , Doyle D, Coffin S, Mair MM, Cowger, Miller EL, Antonio Vital AL, Barrick A, et al. Trends in study quality and reporting in in microplastics research. Abstract 1.09.P-Mo-101, Society of Environmental Toxicology and Chemistry 35th Annual Meeting, Vienna, Austria, May 2025.
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Publication: Abstracts and Presentations
Coffin S, Barrick A, Yeh A, Kukkola A, Carney Almroth B, Miller E, Ahmed KT,…, Kennedy SB , et al. Application of probabilistic species sensitivity distribution modeling to characterize microplastic risk for marine and freshwater environments. Abstract 1.10.P-Tu-096, Society of Environmental Toxicology and Chemistry 35th Annual Meeting, Vienna, Austria, May 2025.
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