Publications

Couture, L.A., M.W. Harris, and L.S. Birnbaum. Characterization of TCDD-induced hydronephrosis relative to cleft palate in C57BL/6N Mice. Presented at the Society of Toxicology Annual Meeting. February 27-March 3, 1989. Atlanta, GA.

Biegel L, Harris MA, Davis D, Rosengren R, Safe L, and Safe S. 1989. 2,2′,4,4′,5,5′-hexachlorobiphenyl as a 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist in C57BL/6J mice. Toxicol Appl Pharmacol. 97:561-571.

Harris, M., M. Romkes, and S. Safe. Human breast cancer cells as models for investigating Ah receptor mediated processes. Dioxin ’89. September 17-22, 1989. Toronto, Canada.

Birnbaum LS, Couture LA, and Elwell MR. 1989. Subchronic effects of exposure to Octachlorodibenzo-p-dioxin (OCDD). Chemosphere. 18(1-6):389-390.

Harris, M., M. Romkes, and S. Safe. Human breast cancer cells as models for investigating Ah receptor mediated processes. Society of Toxicology 28th Annual Meeting. February 27-March 3, 1989. Atlanta, GA.

Couture LA, Harris MW, and Birnbaum LS. 1989. Developmental toxicity of 2,3,4,7,8-pentachlorodibenzofuran (4-PeCDF) in the Fischer 344 rat. Fundam Appl Toxicol. 12:358-366.

Zacharewski, T., M. Harris, and S. Safe. 1989. Structure dependent induction of aryl hydrocarbon hydroxylase of TCDD and related compounds: mechanistic studies. Society of Toxicology 28th Annual Meeting. February 27-March 3, 1989. Atlanta, GA.

Harris, MA, Piskorska-Pliszczynska J, Zacharewski T, Romkes M, and Safe S. 1989. Structure-dependent induction of aryl hydrocarbon hydroxylase in human breast cancer cell lines and characterization of the Ah receptor. Cancer Res. 49:4531-4535.

Randerath, K., K.L. Putman, E. Randerath, M. Harris, T. Zacharewski, and S. Safe. Effects of 2,3,7,8-TCDD and related compounds on the levels of age-dependent i-spot DNA adducts in the liver of female and male Sprague-Dawley rats. Dioxin ’89. September 17-22, 1989. Toronto, Canada.

Harris MA, Zacharewski T, Astroff B, Kamps C, and Safe S. 1989. Characterization of 6-methyl-1,3,8-trichlorodibenzofuran (MCDF) as a 2,3,7,8-TCDD antagonist in male rats: induction of monooxygenases. Chemosphere. 19:769-772.

Harris MA, Zacharewski T, Astroff B, and Safe S. 1989. Partial antagonism of 2,3,7,8-tetrachlorodibenzo-p-dioxin mediated induction of aryl hydrocarbon hydroxylase by 6-methyl-1,3,8-trichlorodibenzofuran: mechanistic studies. Mol Pharmacol. 35:729-735.

Rish W, Patterson J, Lutkenhoff S. 1989. Use of health risk estimates in U.S. EPA. USEPA National Center for Environmental Assessment. Proceedings of the 1989 Annual Meeting of the Society for Risk Analysis. San Francisco, California.

Safe S, Mason G, Sawyer T, Zacharewski T, Harris MA, Yao C, Keys B, Farrell K, Holcomb M, Davis D, Safe L, Piskorska-Pliszcyzynska J, Leece B, Denomme M, Hutzinger O, Thoma H, Chittim B, and Madge J. 1989. Development and validation of in vitro induction assays for toxic halogenated aromatic mixtures: a review. Toxicol Ind Health. 5(5):757-775.

Safe S, Zacharewski T, Safe L, Harris MA, Yao C, and Holcomb M. 1989. Validation of the AHH induction bioassay for the determination of 2,3,7,8-TCDD toxic equivalents. Chemosphere. 18(1-6):941-946.

Zacharewski T, Harris MA, and Safe S. 1989. Induction of cytochrome P450-dependent monooxygenase activities in rat hepatoma H-4-IIE cells in culture by 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds: mechanistic studies using radiolabeled congeners. Arch Biochem Biophys. 272(2):344-355.

Zacharewski T, Harris MA, Safe S, Thoma H, Hauschulz G, Knorr E, and Hutzinger O. 1989. Application of the in vitro AHH induction bioassay for determining 2,3,7,8-TCDD equivalents: pyrolyzed flame retardant mixtures. Chemosphere. 18(1-6):383-387.

Couture, L.A., M.W. Harris, and L.S. Birnbaum. Teratogenicity of 2,3,4,7,8-Pentachlorodibenzofuran (4-PeCDF) in F344 rats. Presented at the Society of Toxicology Annual Meeting. February 15-19, 1988. Dallas, TX.

Birnbaum LS and Couture LA. 1988. Disposition of Octachlorodibenzo-p-dioxin (OCDD) in male rats. Toxicol Appl Pharmacol. 93:22-30.

Harris, M., T. Zacharewski, B. Astroff, C. Kamps, and S. Safe. Characterization of 6-Methyl-1,3,8-Trichlorodibenz-furan (MCDF) as a 2,3,7,8-TCDD Antagonist in Male Rats: Induction of Monooxygenases. Dioxin ’88 Symposium. August 21-26, 1988. Umea, Sweden.

Couture LA, Elwell MR, and Birnbaum LS. 1988. Dioxin-like effects observed in male rats following exposure to Octachlorodibenzo-p-dioxin (OCDD) during a 13-week study. Toxicol Appl Pharmacol. 93:31-46.