Wikoff DS, Vincent MJ, Heintz MM, Pastula ST, Reichert H, Klaren WD, Haws LC . 2025. Application of a quantitative uncertainty assessment to develop ranges of plausible toxicity values when using observational data in risk assessment: A case study examining associations between PFOA and PFOS exposures and vaccine response. Toxicol Sci 204(1):96-115; doi: 10.1093/toxsci/kfae152 . PMID: 39792025.
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Publication: Manuscripts
/ Topics: PFAS , risk assessment , Systematic Review
Nguyen HVM, Cabello E, Dyer D, Fender C , Garcia-Jaramillo M, Hord NG, Austad S, Richardson A, Unnikrishnan A. 2025. Age, sex, and mitochrondrial-haplotype influence gut microbiome composition and metabolites in a genetically diverse rat. Aging 17(2):524-549; doi: 10.18632/aging.206211 . PMID: 40015964.
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Publication: Manuscripts
/ Topics: metabolites
Lea IA , Feifarek D, Mihalchik A, Heintz M, Haws L, Nyambego H, Goyak K, Palermo C, Borghoff SJ . 2025. Evaluation of the endocrine disrupting potential of Di-isodecyl phthalate. Curr Res Toxicol 8:100221; doi: 10.1016/j.crtox.2025.100221 . PMID: 40041033.
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Publication: Manuscripts
/ Topics: phthalates
Kramer A , Vivanco S , Bare J , Panko J . 2025. Analysis of EPA air toxics monitoring data and tools for use in general population exposure assessments: Using acrylonitrile as a case study. J Air Waste Manag Assoc 75(3)181-197; doi: 10.1080/10962247.2024.2438793 . PMID: 39660961.
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Publication: Manuscripts
/ Topics: Air Quality , Exposure Assessment
Pastula ST , Bylsma LC , Rege SV, Lewis RJ, Movva N . 2025. Scoping review of indices to measure a community’s health status. Popul Health Manag 28(1):37-49; doi: 10.1089/pop.2024.0138 . PMID: 39558762.
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Publication: Manuscripts
/ Topics: community health , Epidemiology , scoping review
Pollock D, Marley C, McBride G, Dias M, Kanukula R, Hasanoff S, Price C , et al. 2025. Simulated clinical placements in health care education: A scoping review and evidence and gap map protocol. JBI Evidence Synthesis; https://doi.org/10.11124/JBIES-24-00298 .
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Publication: Protocol Registrations
/ Topics: scoping review
Verwiel A, Rish W . 2025. Multidisciplinary perspectives on cumulative impact assessment for vulnerable communities: Expert elicitation using a Delphi method. Integr Environ Assess Manag 21(2):301-313; doi: 10.1093/inteam/vjae051 . PMID: 39881570.
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Publication: Manuscripts
/ Topics: Air Quality , risk assessment
Seal S, Trapotsi MA, Spjuth O, Singh S, Carreras-Puigvert J, Greene N , Bender A, Carpenter AE. 2025. Cell painting: A decade of discovery and innovation in cellular imaging. Nat Meth 22(2):254-268 ; doi: 10.1038/s41592-024-02528-8 . PMID: 39639168.
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Publication: Manuscripts
/ Topics: computational toxicology
Wikoff D . Use cases of strategic application of ML/AI in the risk assessment process. Toxicology Forum 2025 Winter Meeting, Raleigh, NC, February 2025.
Publication: Abstracts and Presentations
/ Topics: Food science , risk assessment
Wikoff D . Pragmatic solutions for better using evidence-based methods to integrate observational data in food safety assessments. Toxicology Forum 2025 Winter Meeting, Raleigh, NC, February 2025.
Publication: Abstracts and Presentations
/ Topics: Food science , risk assessment
Lagiakos HR, Zou Y, Igawa H, Therrien E, Lawrenz M, Kato M, Svensson M,…, Dingley K , et al. 2025. In silico enabled discovery of KAI-11101, a preclinical DLK inhibitor for the treatment of neurodegenerative disease and neuronal injury. J Med Chem 68(3):2720-2741; doi: 10.1021/acs.jmedchem.4c02074 . PMID: 39670820.
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Publication: Manuscripts
/ Topics: drug development
Payton A, Hickman, Chappel J, Roell KR, Koval LA, Eaves LA, Chou CK,…, Patlewicz G , et al. 2025. TAME 2.0: Expanding and improving online data science training for environmental health research. Front Toxicol 7(Feb 12):1535098; doi: 10.3389/ftox.2025.1535098 . PMID: 40012886.
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Publication: Manuscripts
/ Topics: Exposure Assessment
Borghoff SJ , Rivera B, Fitch S , Buerger AN , Choksi N , Franzen A , Vincent MJ , Covington T , Bus J, Rushton E, Lea IA . 2025. Systematic evaluation of the evidence base on methyl tert -butyl ether supporting a lack of concern for carcinogenic hazard in human based on animal cancer studies and mechanistic data. Curr Res Toxicol 8:100224; doi: 10.1016/j.crtox.2025.100224 . PMID: 40084233.
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Publication: Manuscripts
/ Topics: Cancer , carcinogens , MTBE , risk assessment
O’Brien J, Mitchell C, Auerbach S, Doonan L, Ewald J, Everett L, Faranda A,.., Wheeler MW , et al. 2025. Bioinformatic workflows for deriving transcriptomic points of departure: Current status, data gaps, and research priorities. Toxicol Sci 203(2):147-159; doi: 10.1093/toxsci/kfae145 . PMID: 39499193.
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Publication: Manuscripts
/ Topics: transcriptomics
Rogers JM, Buerger AN , Heintz MM , Palermo CM, Haws LC, Lea IA . 2025. Evaluation of a hypothesized Sertoli cell-based adverse outcome pathway for effects of diisononyl phthalate on the developing testis. Curr Res Toxicol 8:100219; doi: 10.1016/j.crtox.2025.100219 . PMID: 40123861.
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Publication: Manuscripts
/ Topics: phthalates
Lea IA , Buerger AN , Feifarek D, Mihalchik A, Heintz MM, Haws LC , Nyambego H, Goyak K, Palermo C, Borghoff SJ . 2025. Evaluation of the endocrine disrupting potential of Di-isononyl phthalate. Curr Res Toxicol 8:100220; doi: 10.1016/j.crtox.2025.100220 . PMID: 40092461. Corrigendum 8:100233; doi: 10.1016/j.crtox.2025.100233 ; PMID 40529321.
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Publication: Manuscripts
/ Topics: phthalates
Moyer HL , Vergara L, Stephan C, Sakolish C, Ford LC, Tsai HD, Lin HC, Chiu WA, et al. 2025. Comparative analysis of caco-2 cells and human jejunal and duodenal enteroid-derived cells in gel- and membrane-based barrier models of intestinal permeability. Toxicol Sci 204(2):181-197; doi: 10.1093/toxsci/kfaf011 . PMID: 39886939.
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Publication: Manuscripts
/ Topics: modeling
Kennedy SB, Heintz MM, Klaren WD, Wikoff DS, Haws LC, Fitch SE . 2025. An integrated ecotoxicological study reliability framework for use in toxicity value development. Environ Tox Chem 44(4):1142-1153; doi: 10.1093/etojnl/vgaf030 . PMID: 39873747.
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