2011 (43 POSTS)
Kim S, Thompson CM , Kopec AK, Harris MA, Zacharewski TR. Comparison of basal and CrVI-mediated solute carrier gene expression in rodent duodenal epithelium. Presented at Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.
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Topics: chromium
Proctor D , Haws L , Thompson C , Harris M. 2011. Use of mode of action and pharmacokinetics to inform the cancer risk assessment of ingested Cr(VI): A case study. Presented at the Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.
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Topics: Cancer , chromium , mode of action , pharmacokinetics , risk assessment
Staskal-Wikoff D , Budinsky R, Rowlands JC. Single nucleotide polymorphisms in the human aryl hydrocarbon receptor interacting protein (AIP) gene from six ethnic populations. Presented at Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.
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Topics: toxicokinetics
Urban J , Fitzgerald L, Burkhalter B, Staskal D , Harris M, Haws L . BTEX serum levels in the general U.S. population: An analysis of 2003-2004 NHANES dataset. Presented at Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.
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Topics: benzene , NHANES , VOCs
Hinerman J , Herr A. Determining the mechanism of activation of glycoprotein VI. Poster presented to the Ohio Valley Crystallographic Symposium Meeting, Cleveland, OH, November 2011.
Topics: mode of action
Proctor D, Meek B. Using mode of action data to guide quantitative cancer risk assessment: A case study of hexavalent chromium in drinking water. Presented at Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.
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Topics: Cancer , chromium , mode of action , risk assessment , water
2010 (30 POSTS)
Yong M, Kuehn C, Kelsh M , Mitchell M , et al. Associations between platelet count and survival and disease progression in thrombocytopenic patients with myelodysplastic syndromes. Presented at the American Society of Hematology, Orlando, FL, December 2010.
Topics: Epidemiology
Robison TW . Genotoxic impurity guidance – Current experiences, FDA perspective. USP Annual Meeting, New Orleans, LA, December 2010.
Topics: genotoxicity
Tachovsky JA, Haws L . Geostatistical estimation of soil PCDD/F TEQ using sequential Gaussian simulation and the aggregation of results in Midland, MI. Presented at the Society for Risk Analysis Annual Meeting, Salt Lake City, UT, December 2010.
Topics: dioxin
Harris M, Tachovsky JA, Staskal-Wikoff D , Aylward L, Burkhalter B, Simon T, Haws L . Serum concentrations of dioxin-like compounds in a population in Midland, Michigan: An evaluation of the impact of soil exposures. Presented at Dioxin 2010, San Antonio, TX, September 2010.
Topics: dioxin
Sterner TR, Ruark CD, Covington TR , Hack CE, Gearhart JM. Characterizing uncertainty and population variability in a PBPK-PD mathematical model for the oxime HI-6. Poster presented at the Chemical and Biological Defense Science and Technology Conference, Orlando, FL, November 2010.
Topics: modeling , PBPK/PBDE
Makley M, Ruark C, Covington T , Robinson P, Gearhart J. Route of entry model for predicting chemical warfare agent miosis. Poster presented at the Chemical and Biological Defense Science and Technology Conference, Orlando, FL, November 2010.
Topics: modeling
Covington T , Robinson P, Gearhart J. Exploring issues in simulating dermal exposure using a physiologically-based pharmacokinetic-pharmacodynamic (PBPK-PD) model for VX. Poster presented at the Chemical and Biological Defense Science and Technology Conference, Orlando, FL, November 2010.
Topics: PBPK/PBDE , pharmacokinetics
Robison TW . Dealing with positive in vitro mammalian cell genotoxicity assays. IQPC Genotoxicity and Carcinogenicity Testing 2010 Conference, London, UK, October 2010.
Topics: genotoxicity
Robison TW . Dealing with genotoxic impurities from a regulatory perspective. IQPC Genotoxicity and Carcinogenicity Testing 2010 Conference, London, UK, October 2010.
Topics: genotoxicity
Robison TW . Assessing genotoxic impurities. DIA Meeting (Early drug development: Navigating the treacherous rapids). Bethesda, MD, October 2010
Topics: genotoxicity
Haws L . Biomonitoring – A tool for assessing community exposures to air toxics. Presented at the Air Quality 2010 Conference, University of Texas School of Law, November 2010.
Topics: Air Quality , community health , Exposure Assessment
Urban J ,Burkhalter B, Tachovsky JA, Haws L , Harris M. 2010. Evaluation of polychlorinated naphthalenes (PCNs) in Newark Bay sediment. Presented at Dioxin 2010, September 12-17, San Antonio, TX.
Topics: dioxin
Garabrant D, Jiang X , Franzblau A, Adriaens P, Demond A, Gillespie B, Jolliet O, Lepkowski J, Hao W. The University of Michigan Dioxin Exposure Study: Relationship between residential soil, household dust, and serum dioxin levels. Presented at the 31st International Symposium on Halogenated Persistent Organic Pollutants – Dioxin 2010, San Antonio, TX, September 2010.
Topics: dioxin , Exposure Assessment
Hao W, Jolliet O, Jiang X , Garabrant D, Franzblau A, Adriaens P, Demond A, Gillespie B, Lepkowski J. The University of Michigan Dioxin Exposure Study: Dioxin intake due to fish and game consumption in a dioxin-contaminated area. Presented at the 31st International Symposium on Halogenated Persistent Organic Pollutants – Dioxin 2010, San Antonio, TX, September 2010.