2006 (60 POSTS)
David RM, Clewell HJ, Gentry PR, Covington TR , Morgott DA, Marino DJ. 2006. Revised assessment of cancer risk to dichloromethane II. Application of probabilistic methods to cancer risk determinations. Regul Toxicol Pharmacol 45(1):55–65; doi: 10.1016/j.yrtph.2005.12.003 .
View Abstract
Publication: Manuscripts
/ Topics: Cancer , PBPK/PBDE
Marino DJ, Clewell HJ, Gentry PR, Covington TR , Hack CE, David RM, Morgott DA. 2006. Revised assessment of cancer risk to dichloromethane: Part I Bayesian PBPK and dose-response modeling in mice. Regul Toxicol Pharmacol 45(1):44–54; doi: 10.1016/j.yrtph.2005.12.007 .
View Abstract
Publication: Manuscripts
/ Topics: Bayesian modeling , Cancer , dose-response , modeling , PBPK/PBDE , risk assessment
Degregorio MW, Dingley KH , Wurz GT, Ubick E, Turteltaub KW. 2006. Accelerator mass spectrometry allows for cellular quantification of doxorubicin at femtomolar concentrations. Cancer Chemother Pharmacol 57(3):335-342; doi: 10.1007/s00280-005-0060-1 . PMID: 16047147.
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Publication: Manuscripts
/ Topics: Cancer , spectrometry
Tompkins EM, Farmer PB, Lamb JH, Jukes R, Dingley K , Ubick E, et al. 2006. A novel 14C-postlabeling assay using accelerator mass spectrometry for the detection of O6-methyldeoxy-guanosine adducts. Rapid Commun Mass Spectrom 20(5):883–891; doi: 10.1002/rcm.2370 . PMID: 16470516.
View Abstract
Publication: Manuscripts
/ Topics: spectrometry
Borowsky AD, Dingley KH , Ubick E, Turteltaub KW, Cardiff RD, Devere-White R. 2006. Inflammation and atrophy precede prostatic neoplasia in a PhIP-induced rat model. Neoplasia 8(9):708–715; doi: 10.1593/neo.06373 . PMID: 16984728.
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Publication: Manuscripts
/ Topics: carcinogens
Malfatti MA, Dingley KH , Nowell-Kadlubar S, Ubick EA, Mulakken N, Nelson D, Lang NP, et al. 2006. The urinary metabolite profile of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine is predictive of colon DNA adducts after a low-dose exposure in humans. Cancer Res 66(21):10541–10547; doi: 10.1158/0008-5472.CAN-06-1573 . PMID: 17079477.
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Publication: Manuscripts
/ Topics: Cancer , carcinogens
Lau C, Thibodeaux JR, Hanson RG, Narotsky MG, Rogers JM , Lindstrom AB, Strynar MJ. 2006. Effects of perfluorooctanoic acid exposure during pregnancy in the mouse. Toxicol Sci 90(2):510–518; doi: 10.1093/toxsci/kfj105 .
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Publication: Manuscripts
/ Topics: PFAS
Haws L . The use of toxic equivalency factors to assess potential human health risks posed by dioxin-like compounds: Keeping up with the science. Presented at Michigan State University, Toxicology Program Seminar Series, September,, 2006.
Publication: Abstracts and Presentations
/ Topics: dioxin , risk assessment
Wheeler MW , Park RM, Bailer AJ. 2006. Comparing median lethal concentration values using confidence interval overlap or ratio tests. Environ Toxicol Chem 25(5):1441-4; doi: 10.1897/05-320r.1. PMID: 16704080.
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Publication: Manuscripts
/ Topics: risk analysis , risk assessment
Buffler PA, Kelsh MA , Lau EC, Edinboro CH, Barnard JC, Rutherford GW, et al. 2006. Thyroid function and perchlorate in drinking water: An evaluation among California newborns, 1998. Environ Health Persp 114(5):798–804; doi: 10.1289/ehp.8176 . PMID: 16675440.
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Publication: Manuscripts
/ Topics: community health , risk assessment , water
Peabody JW, Nordyke RJ , Tozija F, Luck J, Muñoz JA, Sunderland A, Desalvo K, Ponce N, McCulloch C. 2006. Quality of care and its impact on population health: A cross-sectional study from Macedonia. Soc Sci Med 62(9):2216-24; doi: 10.1016/j.socscimed.2005.10.030 . PMID: 16289739.
View Abstract
Publication: Manuscripts
/ Topics: community health , Health Economics and Outcomes Research (HEOR)
Tinkelman DG, Price DB, Nordyke RJ , Halbert RJ, Isonaka S, Nonikov D, Juniper EF, Freeman D, et al. 2006. Symptom-based questionnaire for differentiating COPD and asthma. Respiration 73(3):296-305; doi: 10.1159/000090141 . PMID: 16330874.
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Publication: Manuscripts
/ Topics: Epidemiology
Nordyke RJ , Chang CH, Chiou CF, Wallace JF, Yao B, Schwartzberg LS. 2006. Validation of a patient satisfaction questionnaire for anemia treatment, the PSQ-An. Health Qual Life Outcomes 4(May3):28; doi: 10.1186/1477-7525-4-28 . PMID: 16672069.
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Publication: Manuscripts
/ Topics: Cancer , Health Economics and Outcomes Research (HEOR)
Van den Berg M, Birnbaum L, Denison M, De Vito M, Farland W, Feeley M, Fiedler H, Hakansson H, Hanberg A, Haws LC , Rose M, Safe S, Schrenk D, Tohyama C, Tritscher A, Tuomisto J, Tysklind M, Walke Nr, Peterson RE. 2006. The 2005 World Health Organization reevaluation of human and mammalian toxic equivalency factors for dioxins and dioxin-like compounds. Toxicol Sci 93(2):223-241; doi: 10.1093/toxsci/kfl055 .
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Publication: Manuscripts
/ Topics: dioxin
Leighton JK, Brown P, Ellis A, Harlow P, Harrouk W, Pine PS, Robison T , Rosario L, Thompson K. 2006. Workgroup Report: Review of genomic data based on experience with mock submissions: View of the CDER Pharmacology Toxicology Nonclinical Pharmacogenomics Subcommittee. Environ Health Perspect 114:573-578; doi: 10.1289/ehp.8318 . PMID: 16581548.
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Publication: Manuscripts
/ Topics: drug development , nonclinical safety assessment , pharmacology
Staskal DF , Diliberto JJ, Birnbam LS. 2006. Disposition of BDE 47 in developing mice. Toxicol Sci 90(2):309-16; doi: 10.1093/toxsci/kfj098 . PMID: 16407092.
View Abstract
Publication: Manuscripts
/ Topics: flame retardants , PBPK/PBDE
Jackson MA, Lea I , Rashid A, Peddada SD, Dunnick JK. 2006. Genetic alterations in cancer knowledge system: Analysis of gene mutations in mouse and human liver and lung tumors. Toxicol Sci 90(2):400–418; doi: 10.1093/toxsci/kfj101 . PMID: 16410370.
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Publication: Manuscripts
/ Topics: Cancer
Hamernik K, Eskes C, Merrill J, Choksi N , Allen D, Truax J, et al. 2006. ICCVAM-NICEATM-ECVAM symposium on mechanisms of chemically-induced ocular injury and recovery: Current understanding and knowledge gaps. ALTEX 23 Suppl:322–324 .
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Publication: Abstracts and Presentations
/ Topics: Exposure Assessment
Covington TR , Gentry P, Van Landingham CB, Clewell HJ. Issues in using Markov Chain Monte Carlo analysis to calibrate a PBPK model for use in risk assessment: Case studies with dichloromethane and perchloroethylene. Poster presented at the Society of Toxicology Annual Meeting, San Diego, CA, March 2006.
Publication: Abstracts and Presentations
/ Topics: PBPK/PBDE
Richardson VM, Staskal DF , Diliberto JJ, Birnbaum LS. Effects of BDE 47 on nuclear receptor regulated genes and implications for thyroid hormone disruption. Society for Toxicology 45th Annual Meeting, San Diego, CA, March 2006.