2023 (138 POSTS)
Richard AM, Lougee R, Adams M, Hidle H, Yang C, Rathman J, Magdziarz T, Bienfait B, Williams AJ, Patlewicz G . 2023. A new CSRML structure-based fingerprint method for profiling and categorizing per- and polyfluoroalkyl substances (PFAS). Chem Res Toxicol 36(3):508–534; doi: 10.1021/acs.chemrestox.2c00403 . PMID: 36862450.
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Publication: Manuscripts
/ Topics: PFAS
Carstens KE, Freudenrich T, Wallace K, Choo S, Carpenter A, Smeltz M, Clifton MS,…, Patlewicz G , et al. 2023. Evaluation of per- and polyfluoroalkyl substances (PFAS) in vitro toxicity testing for developmental neurotoxicity. Chem Res Toxicol 36(3):402–419; doi: 10.1021/acs.chemrestox.2c00344 . PMID: 36821828.
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Publication: Manuscripts
/ Topics: PFAS
Pastula S , Suh M , Jiang X , Reichert H , Movva N , Fryzek J, Simões EAF. Respiratory syncytial virus (RSV) and bronchiolitis epidemiology among the United States infant Medicaid populations in seven states. Poster 191, International Society for Pharmacoepidemiology (ICPE) annual meeting, Halifax, Nova Scotia, August 2023.
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Publication: Abstracts and Presentations
/ Topics: Epidemiology
Thompson CM, Wikoff DS , Proctor DM, Harris MA. An evaluation of risk assessments on hexavalent chromium [Cr(VI)]: The past, present, and future of mode of action research. Poster presented at Society of Toxicology 62nd Annual Meeting, Nashville, TN, March 2023.
Publication: Abstracts and Presentations
/ Topics: chromium , mode of action , risk assessment
Franzen AC, Thompson CM, Brorby GP , Wikoff DS , Ilkbahar Z, Doepker C . Risk assessment of three smoke flavoring primary products currently under re-evaluation by EFSA. Poster presented at Society of Toxicology 62nd Annual Meeting, Nashville, TN, March 2023.
Publication: Abstracts and Presentations
/ Topics: food additives , food safety , Food science , risk assessment
Fitch S, Rogers J, Marty S, Ellis-Hutchings R, Becker R, Wikoff D . Development of a study quality tool for use in a systematic review of literature reporting microplastic exposure and reproductive and developmental toxicity. Poster presented at Society of Toxicology 62nd Annual Meeting, Nashville, TN, March 2023.
Publication: Abstracts and Presentations
/ Topics: microplastics , reproductive toxicology , Systematic Review
Sakolish C, Moyer H , Fergusson SS, Chiu WA, Rusyn I. Analysis of reproducibility and robustness of PhysioMimix T12, a proximal renal tubule microphysiological system for studies of pharmacokinetics and toxicological assessment of drugs and chemicals. Abstract 3635, Society of Toxicology 62nd Annual Meeting, Nashville, TN, March 2023.
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Publication: Abstracts and Presentations
/ Topics: pharmacokinetics
Moyer HL , Kim S, Lam BP, Valdiviezo A, Richardson L, Menon R, Rusyn I, Han A. Evaluating mechanistic underpinnings of environmental chemical effects on feto-maternal interface using a human organ-on-chip model. Abstract 3007, Society of Toxicology 62nd Annual Meeting, Nashville, TN, March 2023. Winner, Perry J. Gehring Best Graduate Student Abstract Award, Risk Assessment Specialty Section.
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Publication: Abstracts and Presentations
/ Topics: Exposure Assessment , modeling
Schaefer H . Evidence-based methods in toxicology: Progress in the past decade and collaborative projections for the future. Abstract 1218, Society of Toxicology 62nd Annual Meeting, Nashville, TN, 2023.
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Publication: Abstracts and Presentations
/ Topics: Systematic Review
Thompson CM , Proctor DM , Harris MA. 2023. Letter to “Chepelev et al. Establishing a quantitative framework for regulatory interpretation of genetic toxicity dose–response data: Margin of exposure case study of 48 compounds with both in vivo mutagenicity and carcinogenicity dose–response data.” Environ Mol Mutagen 64(4):259–260; doi: 10.1002/em.22537 . PMID: 36916184.
Publication: Manuscripts
/ Topics: carcinogens , dose-response , regulatory toxicology
Sterner TR, Covington TR , Mattie DR. 2023. Complex mixtures: Array PBPK modeling of jet fuel components. Toxics 11(2):187; doi: 10.3390/toxics11020187 . PMID: 36851061.
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Publication: Manuscripts
/ Topics: PBPK/PBDE
Wright PSR, Briggs KA, Thomas R, Smith GF, Maglennon G, Mikulskis P, Chapman M, Greene N , et al. 2023. Statistical analysis of preclinical interspecies concordance of histopathological findings in the eTOX database. Regul Toxicol Pharmacol 138(Feb):105308; doi: 10.1016/j.yrtph.2022.105308 . PMID: 36481279.
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Publication: Manuscripts
/ Topics: computational toxicology , drug development
Patlewicz G , Shah I. 2023. Towards systematic read-across using Generalized Read-Across (GenRA). Comput Toxicol 25(Feb):100258; doi: 10.1016/j.comtox.2022.100258 . PMID: 37693774.
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Publication: Manuscripts
/ Topics: NAMs
Wright PSR, Smith GF, Briggs KA, Thomas R, Maglennon G, Mikulskis P, Chapman M, Greene N , et al. 2023. Retrospective analysis of the potential use of virtual control groups in preclinical toxicity assessment using the eTOX database. Regul Toxicol Pharmacol 138(Feb):105309; doi: 10.1016/j.yrtph.2022.105309. PMID: 36481280.
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Publication: Manuscripts
/ Topics: drug development , modeling
Houck K, Paul Friedman K, Feshuk M, Patlewicz G , Smeltz M, Clifton S, Wetmore BA, Velichko S, et al. 2023. Evaluation of 147 perfluoroalkyl substances for immunotoxic and other (patho)physiological activities through phenotypic screening of human primary cells. ALTEX 40(2):248–270; doi: 10.14573/altex.220304 . PMID: 36129398.
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Publication: Manuscripts
/ Topics: chemical safety assessment , PFAS
Adams M, Hilde H, Chang D, Richard A, Williams AJ, Shah I, Patlewicz G . 2023. Development of a CSRML version of the Analog Identification Methodology (AIM) fragments and their evaluation within the Generalized Read-Across (GenRA) approach. Comput Toxicol 25(Feb):100256; doi: 10.1016/j.comtox.2022.100256 . PMID: 36733411.
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Publication: Manuscripts
/ Topics: NAMs
Pang F, Dean R, Jensen I , Bean K, Fields C, Miller B. 2023. The cost-effectiveness of OTL-200 for the treatment of metachromatic leukodystrophy (MLD) in the US. Mol Gene Metab 138(2):107258; doi: 10.1016/j.ymgme.2022.107258 .
Publication: Abstracts and Presentations
/ Topics: Health Economics and Outcomes Research (HEOR) , Metachromatic leukodystrophy (MLD)
Wheeler MW , Lim S, House JS, Shockley KR, Bailer AJ, Fostel J, Yang L, Talley D, Raghuraman A, Gift JS. 2023. ToxicR: A computational platform in R for computational toxicology and dose–response analyses. Comp Toxicol 25(Feb):100259; doi: 10.1016/j.comtox.2022.100259 . PMCID: PMC9997717.
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