2018 (156 POSTS)
Thompson CM , Suh M , Proctor DM , Harris MA. Ten factors for considering the mode of action of Cr(VI)-induced intestinal tumors in rodents. Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.
View Abstract
Publication: Abstracts and Presentations
/ Topics: chromium , mode of action
Proctor DM . Updating the regulatory risk assessment for hexavalent chromium in California: Implications for regulatory standards. Association of Environmental Health Sciences San Diego, CA, March 2018.
Publication: Abstracts and Presentations
/ Topics: chromium , regulatory toxicology , risk assessment
Proctor DM . Hexavalent chromium in drinking water: When is the science sufficient to deviate from defaults? Invited Speaker, Genetic and Environmental Toxicology Association (GETA). Thresholds in Toxicology and Risk Assessment Fall Symposium, Oakland, CA, November 2018.
Publication: Abstracts and Presentations
/ Topics: chromium , water
Movva N , Jani A. 2018. The value of pay-for-performance in England: An evaluation of NHS England’s Quality Outcomes Framework. Value in Healthcare Review Working Paper No. 2; University of Oxford Research Archive .
View Abstract
Publication: Manuscripts
/ Topics: Health Economics and Outcomes Research (HEOR)
DeGeorge J, Robertson S, Butler L, Derzi M, Stoch SA, Diaz D, Hartke J,…, Greene N . 2018. An industry perspective on the 2017 EMA guideline on first‐in‐human and early clinical trials. Clin Pharm Ther 103(4):566-569; doi: 10.1002/cpt.984 . PMID: 29285748.
View Abstract
Publication: Manuscripts
/ Topics: drug development
Clippinger A, Allen D, Jarabek AM, Corvaro M, Gaça M, Gehen S, Hotchkiss JA, Patlewicz G , et al. 2018. Alternative approaches for acute inhalation toxicity testing to address global regulatory and non-regulatory data requirements: An international workshop report. Toxicol In Vitro 48(April):53-70; doi: 10.1016/j.tiv.2017.12.011 . PMID: 29277654.
View Abstract
Publication: Manuscripts
/ Topics: inhalation toxicology , NAMs , regulatory toxicology
Rish W , Pfau EJ. 2018. Bounding analysis of drinking water health risks from a spill of hydraulic fracturing flowback water. Risk Analysis 38(4):724-754; doi: 10.1111/risa.12884 . PMID: 28973831.
View Abstract
Publication: Manuscripts
/ Topics: Environmental Science , fracking , risk assessment , water
Kovochich M, Fung ES, Donovan E, Unice KM, Paustenbach DJ, Finley BL . 2018. Characterization of wear debris from metal-on-metal hip implants during normal wear versus edge-loading conditions. J Biomed Mater Res 106(3):986–996; doi: 10.1002/jbm.b.33902 . PMID: 28480531.
View Abstract
Publication: Manuscripts
/ Topics: Metals
Fryzek J, Reichert H , Summers N, Townes L, Deuson R, Alexander DD, Vanderpuye-Orgle J. 2018. Indirect treatment comparison of cabazitaxel for patients with metastatic castration-resistant prostate cancer who have been previously treated with a docetaxel-containing regimen. PLoS One 13(4):e0195790; doi: 10.1371/journal.pone.0195790 . PMID: 29641566.
View Abstract
Publication: Manuscripts
/ Topics: Cancer , drug development
Lea IA , Borghoff S , Travlos GS. 2018. Electrolytes, blood gases and acid-base balance. In: Kurtz DM, Travlos GS (eds): The Clinical Chemistry of Laboratory Animals (3rd edition). CRC Press, Boca Raton, FL; doi: 10.1201/9781315155807 .
View Abstract
Publication: Book Chapters
/ Topics: mode of action
Kovochich M, Fung D, Unice KM, Mahoney SL, Paustenbach DJ, Finley BL . Understanding divergent outcomes in MoM-THA patient populations with well-fixed components: A critical appraisal of patient management protocols and revision trends (2000-2017). Poster presentation at Society of Toxicology 57th Annual Meeting, San Antonio, TX, 2018.
Publication: Abstracts and Presentations
/ Topics: Metals
Kovochich M, Fung ES, Mahoney SL, Unice KM, Fung D, Paustenbach DJ, Finley BL . Characterizing cytotoxic and inflammatory responses to metal-on-metal wear debris from normal versus edge-loading conditions. Poster presentation at Society of Toxicology 57th Annual Meeting, San Antonio, TX, 2018.
Publication: Abstracts and Presentations
/ Topics: Metals
Burns AM , Benson SM, Best E, Hollins DM, Finley BL . An ecological epidemiology investigation of talc consumption in the US and trends in female cancer rates. Poster presentation at Society of Toxicology 57th Annual Meeting, San Antonio, TX, 2018.
Publication: Abstracts and Presentations
/ Topics: Cancer , Epidemiology , talc
Brorby GP . The ongoing controversy surrounding the effects of short-term exposure to trichloroethylene. Presented at the Association for Environmental Health and Sciences Foundation Annual International Conference, San Diego, CA, March 2018.
Publication: Abstracts and Presentations
/ Topics: trichloroethylene
Thompson CM , Kirman CR, Hays SM, Suh M , Harvey SE , Proctor DM , Rager JE, Haws LC , Harris MA. 2018. Integration of mechanistic and pharmacokinetic information to derive oral reference dose and margin-of-exposure values for hexavalent chromium. J Appl Toxicol 38:351–365. doi: 10.1002/jat.3545 . PMID: 29064106.
View Abstract
Publication: Manuscripts
/ Topics: chromium , pharmacokinetics
Winiwarter S, Ahlberg E, Watson E, Oprisiu I, Mogemark M, Noeske T, Greene N . 2018. In silico ADME in drug design–Enhancing the impact. ADMET DMPK 6(1):15-33; doi: 10.5599/admet.6.1.470 .
View Abstract
Publication: Manuscripts
/ Topics: drug development , pharmacology
Covington TR , Ott DK, Gearhart JM, Pangburn HA. Development of a physiologically-based pharmacokinetic model for the virtual high-performance aircraft pilot. Poster presented at Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.
Publication: Abstracts and Presentations
/ Topics: modeling , pharmacokinetics
Fisk L, Greene N , Naven R. 2018. Physicochemical properties and structural alerts. In: Chen M, Will Y (eds), Drug-Induced Liver Toxicity, Humana: New York, pp. 61-76; doi: 10.1007/978-1-4939-7677-5_4 .
View Abstract
Publication: Book Chapters
/ Topics: drug development , pharmacokinetics
Czerkies L, Kineman B, Cohen S, Reichert H , Carvalho R. A pooled analysis of growth and tolerance of infants exclusively fed a partially hydrolyzed whey or intact protein-based infant formulas. Presented at the 5th International Conference on Nutrition and Growth, Paris, France, March 2018.