2024 (159 POSTS)
O’Brien J, Mitchell C, Auerbach S, Doonan L, Ewald J, Everett L, Faranda A, Johnson K, Reardon A, Rooney J., Wheeler MW , et al. 2024. Bioinformatic workflows for deriving transcriptomic points of departure: Current status, data gaps, and research priorities. Toxicol Sci 203(2):147-159; doi: 10.1093/toxsci/kfae145 . PMCID: PMC11775421.
View Abstract
Publication: Manuscripts
/ Topics: transcriptomics
Banerjee A, Kar S, Roy K, Patlewicz G , Charest N, Benfenati E, Cronin MTD. 2024. Molecular similarity in chemical informatics and predictive toxicity modeling: From quantitative read-across (q-RA) to quantitative read-across structure-activity relationship (q-RASAR) with the application of machine learning. Crit Rev Toxicol 54(9):659-684; doi: 10.1080/10408444.2024.2386260 . PMID: 39225123.
View Abstract
Publication: Manuscripts
/ Topics: modeling
Farris DP, Lebo RA, Price C. 2024. Designing a framework for curriculum building in systematic review competencies for librarians: A case report. J Med Libr Assoc 4:357–363; doi: 10.5195/jmla.2024.1930 .
View Abstract
Publication: Manuscripts
/ Topics: Systematic Review
Hagan B, Patlewicz G , Shah I. Metabolic similarity in read-across prediction: A case study using graph convolutional networks to predict genotoxicity outcomes from metabolic networks. Abstract 62, American Society for Cellular and Computation Toxicology 13th Annual Meeting, Research Triangle Park, NC, October 2024.
Publication: Abstracts and Presentations
/ Topics: computational toxicology , read-across
Leary AJ, Patlewicz G , Shah I. An exploration of the use of hybrid fingerprints in generalized read-across and their impact on predictive performance for selected in vivo toxicity outcomes. Abstract 42, American Society for Cellular and Computation Toxicology 13th Annual Meeting, Research Triangle Park, NC, October 2024.
Publication: Abstracts and Presentations
/ Topics: computational toxicology , read-across
Rogers JD, Patlewicz G , Baker E, Bettmann A, Clippinger A, Paul Friedman K. High-throughput safety pharmacology screening to better understand data-poor chemicals. Abstract 57, American Society for Cellular and Computation Toxicology 13th Annual Meeting, Research Triangle Park, NC, October 2024.
Publication: Abstracts and Presentations
/ Topics: pharmacology
Seo S, Healey BE, McLin R, Sacks NC , Benson CJ, Citrome L. 2024. Impact of demographics and insurance coverage on schizophrenia treatment and healthcare resource utilization within an integrated healthcare system. Neuropsychiatr Dis Treat 20(Sept 26):1837–1848; doi: 10.2147/NDT.S473492 . PMID: 39351585.
View Abstract
Publication: Manuscripts
/ Topics: Health Economics and Outcomes Research (HEOR)
DiBiase JF, Scharnetzki E, Edelman E, Reed EK, Helbig P, Rueter J, Miesfeldt S, Frankenfeld CL , et al. 2024. Socioeconomic and urban-rural disparities in genome-matched treatment receipt and survival after genomic tumor testing. JNCI Cancer Spectr 8(5):pkae090; doi: 10.1093/jncics/pkae090 . PMID: 39312685.
View Abstract
Publication: Manuscripts
/ Topics: Cancer , Epidemiology , Health Economics and Outcomes Research (HEOR)
Wilson KP, Valazza E, Price C. 2024. Video modeling to support social communication goals of autistic adults: A tutorial. Am J Speech Lang Pathol 33(5):2249–2265; doi: 10.1044/2024_AJSLP-23-00479 .
View Abstract
Publication: Manuscripts
/ Topics: evidence-based reviews , modeling
Keeton KA, Blanchette A, Benson SM, Covell LT , Madl AK. Analysis and comparison of nicotine pharmacokinetics of modern oral nicotine pouches. Poster Presentation 48 at the 77th Tobacco Science Research Conference, Atlanta, GA, September 2024.
Publication: Abstracts and Presentations
/ Topics: pharmacokinetics
Monticello TM , Potter DM, Huang Q, Hart TK, Shuey D, Troth S, Vergis JM, Tassew N, et al. 2024. Do longer duration nonclinical toxicology studies provide predictive clinical safety value? The IQ Consortium longer duration nonclinical to clinical translational database. Toxicol Appl Pharmacol 492(Sept 5):117087; doi: 10.1016/j.taap.2024.117087 .
View Abstract
Publication: Manuscripts
/ Topics: nonclinical safety assessment
Perry CS , Verwiel AH , Covington TR , Proctor DM . 2024. PBPK modeling demonstrates that exposure time adjustment is unnecessary for setting an acute manganese inhalation exposure guideline. Regul Toxicol Pharmacol 153(Nov):105698; doi: 10.1016/j.yrtph.2024.105698 . PMID: 39251127.
View Abstract
Publication: Manuscripts
/ Topics: Air Quality , Manganese , modeling , PBPK/PBDE
Patlewicz G , Judson RS, Williams AJ, Butler T, Barone Jr. S, Carstens K, Cowden J, Dawson JD, et al. 2024. Development of chemical categories for per- and polyfluoroalkyl substances (PFAS) and the proof-of-concept approach to the identification of potential candidates for tiered toxicological testing and human health assessment. Comput Toxicol 131(Sep 1):100327; doi: 10.1016/j.comtox.2024.100327 . PMID: 40547594.
View Abstract
Publication: Manuscripts
/ Topics: PFAS
Gawehn E, Greene N , Miljković F, Obrezanova O, Subramanian V, Trapotsi M, Winiwarter S. 2024. Perspectives on the use of machine learning for ADME prediction at AstraZeneca. Xenobiotica 54(7):368-378; doi: 10.1080/00498254.2024.2352598 .
View Abstract
Publication: Manuscripts
/ Topics: pharmacokinetics
Reynolds JI , Choi J, Johnson BP. 2024. Crowdsourcing AOP development: Leveraging the thesis literature review to identify knowledge gaps and facilitate research translation. Curr Res Toxicol 7(Aug 8):100191; doi: 10.1016/j.crtox.2024.100191 . PMID: 39205829.
View Abstract
Publication: Manuscripts
/ Topics: Adverse outcome pathways (AOPs) , risk assessment
Barker TH, McBride GM, Dias M, Price C , Munn Z. 2024. Contextual factors and G6PD diagnostic testing: A scoping review and evidence and gap map. Malaria J 23(1):241; doi: 10.1186/s12936-024-05050-6 .
View Abstract
Publication: Manuscripts
/ Topics: malaria , scoping review
Singh DK, Reynolds JI , Johnson BP. Low-cost laser welding for rapid prototyping of microfluidic, Lab-on-a-Chip, and microphysiological models. Mid-Michigan Symposium for Undergraduate Research Experiences, East Lansing, MI, 2024.
Publication: Abstracts and Presentations
/ Topics: micromachining , modeling
Jackson JW, Frederick C Streich Jr, Pal A, Coricor G, Boston C, …, Wood M , et al. 2024. An antibody that inhibits TGF-β1 release from latent extracellular matrix complexes attenuates the progression of renal fibrosis. Sci Signal 17(844):eadn6052; doi: 10.1126/scisignal.adn6052 . PMID: 38980922.
View Abstract
Publication: Manuscripts
/ Topics: drug development
Pollock D, Bailey HD, Hasanoff S, Munn Z, Valenzuela C, Stern C, Price C, et al . 2024. First Nations Peoples’ perceptions, knowledge and beliefs regarding stillbirth prevention and bereavement practices: A mixed methods systematic review. Women Birth 37(4):101604; doi: 10.1016/j.wombi.2024.101604 .
View Abstract
Publication: Manuscripts
/ Topics: Systematic Review
Wingrat J, Price C , Wright T. 2024. Facilitators of and barriers to caregiver adherence to home therapy recommendations for infants and children with neuromotor and neuromuscular diagnoses: A scoping review. Am J Occup Ther 78(5):7805205070; doi: 10.5014/ajot.2024.050567 .
View Abstract