Publications

Thompson CM, Gentry R. An updated mode-of-action analysis for formaldehyde-induced nasal tumors in rodents: A case study using the IPCS MOA and human relevance frameworks. Poster at Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.

Chappell GA, Rager JE, Wolf JC, Babic M, LeBlanc KJ, Ring CL, Harris MA, Thompson C. Similarities in the transcriptomic signatures in the duodenum of mice exposed to hexavalent chromium, captan, or folpet inform the mechanisms of chemical-induced mouse small intestine cancer. Presentation at Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.

Ring CL, Urban J, Wikoff D, Thompson C, Budinsky RA, Haws LC. Application of systematic review and quantitative evidence integration methods to support risk assessment: Characterization of the dose-response relationship between exposure to dioxin-like compounds (DLC) and sperm count. Poster at Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.

Clewell RA, Thompson CM, Clewell HJ. 2019. Dose-dependence of chemical carcinogenicity: Biological mechanisms for thresholds and implications for risk assessment. Chem Biol Interact 301(March 1):112–127; doi: 10.1016/j.cbi.2019.01.025. PMID: 30763550.

Urban J, Wikoff D, Haws L, Fitch S, Ring C, Thompson C, Suh M. 2018. Systematic review protocol: Systematic review and meta-regression to characterize the dose-response relationship between exposure to dioxin-like compounds during sensitive windows of development and reduced sperm count. Zenodo. http://doi.org/10.5281/zenodo.1636357.

Wikoff DS, Thompson C, Rager J, Chappell G, Fitch S, Doepker C. 2018. Benefit-risk analysis for foods (BRAFO): Evaluation of exposure to dietary nitrates. Food Chem Toxicol 120(Oct):709-723; doi: 10.1016/j.fct.2018.08.031. PMID: 30134152.

Thompson CT, Suh M, Chappell G, Borghoff S, Ellis-Hutchings, R, Wiench, K, Finch, L, Proctor DM. 2018. Assessment of the mode of action underlying development of forestomach tumors in rodents following oral exposure to ethyl acrylate and relevance to humans. Regul Toxicol Pharmacol 96(Jul):178–189; doi: 10.1016/j.yrtph.2018.05.006. PMID: 29738809.

Proctor DM, Suh M, Chappell G, Borghoff SJ, Thompson CM, Wiench K, Finch L, Ellis-Hutchings R. 2018. An adverse outcome pathway (AOP) for forestomach tumors induced by non-genotoxic initiating events. Regul Toxicol Pharmacol 96(July):30-40; doi: 10.1016/j.yrtph.2018.04.016. PMID: 29684431.

Moffat I, Martinova N, Seidel C, Thompson CM. 2018. Hexavalent chromium in drinking water. J AWWA 110(5):E22-E35; doi: 10.1002/awwa.1044.

Suh M, Proctor DM, Chappell G, Rager JE, Thompson CM, Borghoff S, Finch L, Ellis-Hutchings R, Wiench K. 2018. A review of the genotoxic, mutagenic, and carcinogenic potentials of several lower acrylates. Toxicol 402-403(June 1):50-67; doi: 10.1016/j.tox.2018.04.006. PMID: 29689363.

Thompson CM, Wolf JC, Suh M, Proctor DM, Haws LC, Harris MA. Toxicity and recovery in the duodenum of B6C3F1 mice following treatment with intestinal carcinogens; captan, folpet, and hexavalent chromium: Evidence for an adverse outcome pathway. Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.

Thompson CM, Suh M, Proctor DM, Harris MA. Ten factors for considering the mode of action of Cr(VI)-induced intestinal tumors in rodents. Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.

Thompson CM, Kirman CR, Hays SM, Suh M, Harvey SE, Proctor DM, Rager JE, Haws LC, Harris MA. 2018. Integration of mechanistic and pharmacokinetic information to derive oral reference dose and margin-of-exposure values for hexavalent chromium. J Appl Toxicol 38:351–365. doi: 10.1002/jat.3545. PMID: 29064106.

Thompson CM, Wolf, JC, McCoy A, Suh M, Proctor DM, Kirman CR, Haws LC, Harris MA. 2017. Comparison of toxicity and recovery in the duodenum of B6C3F1 mice following treatment with intestinal carcinogens captan, folpet, and hexavalent chromium. Toxicol Pathol 45(8):1091–1101; doi: 10.1177/019262331yy4324. PMID: 29161989.

Thompson CM, Suh M, Proctor DM, Haws LC, Harris MA. 2017. Ten factors for considering the mode of action of Cr(VI)-induced gastrointestinal tumors in rodents. Mutat Res 823(Nov):45-57; doi: 10.1016/j.mrgentox.2017.08.004. PMID: 28985946.

Rager JE, Auerbach SS, Chappell GA, Martin E, Thompson C, Fry RC. 2017. Benchmark dose modeling estimates of the concentrations of inorganic arsenic that induce changes to the neonatal transcriptome, proteome, and epigenome in a pregnancy cohort. Chem Res Toxicol 30(10):1911-1920; doi: 10.1021/acs.chemrestox.7b00221. PMID: 28927277.

Thompson CM, Young RR, Dinesdurage H, Suh M, Harris MA, Rohr AC, Proctor DM. 2017. Assessment of the mutagenic potential of hexavalent chromium in the duodenum of Big Blue® rats. Toxicol Appl Pharmacol 330(1):48-52; 10.1016/j.taap.2017.07.002. PMID: 28687238.

Rager JE, Ring CL, Fry RC, Suh M, Proctor DM, Haws L, Harris MA, Thompson CM. 2017. High-throughput screening data interpretation in the context of in vivo transcriptomic responses to oral Cr(VI) exposure. Toxicol Sci 158(1):199–212; doi: 10.1093/toxsci/kfx085. PMID: 28472532.

Thompson C, Rager J, Suh M, Proctor D, Haws L, Harris M. Mechanistic support for nonlinear risk assessment of rat oral cavity tumors induced by exposure to Cr(VI) in drinking water. Poster presented at 56th Society of Toxicology Annual Meeting. March 15, Baltimore, MD, March 2017.

Thompson C, Kirman C, Suh M, Proctor D, Haws L, Harris M, Hays S. Risk assessment of oral exposure to Cr(VI): Integration of mode of action, pharmacokinetics, and dose-response modeling. Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.