Sahmel J, Avens HJ, Scott PK, Unice K, Burns A , Barlow CA, Madl AK, Henshaw J, Paustenbach DJ. 2015. Measured removal rates of chrysotile asbestos fibers from air and comparison with theoretical estimates based on gravitational settling and dilution ventilation. Inhal Toxicol 27(14):787-801; doi: 10.3109/08958378.2015.1110216 . PMID: 26671197.
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Publication: Manuscripts
/ Topics: asbestos
James RC, Britt JK , Halmes NC, Guzelian PS. 2015. Evidence-based causation in toxicology: A 10-year retrospective. Hum Exp Toxicol 34(12):1245–1252; doi: 10.1177/0960327115601767 . PMID: 26614812.
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Publication: Manuscripts
/ Topics: evidence-based reviews
Wirbisky SE , Freeman JL. 2015. Atrazine exposure and reproductive dysfunction through the hypothalamus-pituitary-gonadal (HPG) axis. Toxics 3(4):414–450; doi: 10.3390/toxics3040414 . PMID: 28713818.
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Publication: Manuscripts
/ Topics: atrazine , reproductive toxicology
Madl AK, Kovochich M, Liong M, Finley BL , Paustenbach DJ, Oberdorster G. 2015. Toxicology of wear particles of cobalt-chromium alloy metal-on-metal hip implants Part II: Importance of physiochemical properties and dose in animal and in vitro studies as a basis for risk assessment. Nanomed: Nanotech Biol Med 11(5):1285–1298; doi: 10.1016/j.nano.2015.02.006 . PMID: 25735266.
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Publication: Manuscripts
/ Topics: chromium , cobalt , Metals , risk assessment
Unice KM, Bare JL, Kreider ML, Panko JM . Evaluation of leachate from tire and road wear particles (TRWP) upflow percolation column tests. Poster at Society of Environmental Toxicology and Chemistry, 36th Annual Meeting, Salt Lake City, UT, November 2015.
Publication: Abstracts and Presentations
/ Topics: tire particles (TRWP)
Wheeler MW, Park R, Bailer A, Whittaker C. 2015. Historical context and recent advances in exposure-response estimation for deriving occupational exposure limits. J Occup Environ Hyg 12(sup1):S7-S17; doi: 10.1080/15459624.2015.1076934 . PMCID: PMC4685605.
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Publication: Manuscripts
/ Topics: benchmark dose estimation (BMD) , dose-response , modeling , Occupational , Occupational exposure limits (OELs)
Katz AJ, Chia VM, Schoonen WM, Kelsh MA . 2015. Acute lymphoblastic leukemia: An assessment of international incidence, survival, and disease burden. Cancer Causes Control 26(11):1627–1642; doi: 10.1007/s10552-015-0657-6 . PMID: 26376890.
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Publication: Manuscripts
/ Topics: Cancer , Epidemiology
Strickland J, Zang Q, Paris M, Kleinstreuer N, Lehmann DM, Allen D, Choksi N , et al. Machine learning approaches for predicting human skin sensitization hazard. Poster presented at FutureToxIII, Baltimore, MD, November 2015
Publication: Abstracts and Presentations
/ Topics: Exposure Assessment
Wikoff D , Doepker C , Welsh B, Goldberger J, Lieberman H, Myers E, O’Brien C, Peck J, Tenebein M, Weaver C. 2015. Systematic review of the adverse behavioral effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children. PROSPERO 2015:CRD42015027413 Available from http://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42015027413 (Systematic Review Protocol Registration)
Publication: Protocol Registrations
/ Topics: Food science , Systematic Review
Shah F, Leung L, Barton HA, Will Y, Rodrigues AD, Greene N , Aleo MD. 2015. Setting clinical exposure levels of concern for drug-induced liver injury (DILI) using mechanistic in vitro assays. Toxicol Sci 147(2):500-14; doi: 10.1093/toxsci/kfv152 . PMID: 26206150.
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Publication: Manuscripts
/ Topics: drug development , safety assessment
Becker RA, Patlewicz G , Simon T, Rowlands JC, Budinsky RA. 2015. The adverse outcome pathway for rodent liver tumor promotion by sustained activation of the aryl hydrocarbon receptor. Regul Toxicol Pharmacol 73(1):172-190; doi: 10.1016/j.yrtph.2015.06.015 . PMID: 26145830.
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Publication: Manuscripts
/ Topics: Adverse outcome pathways (AOPs) , mode of action
Bottomley AL , Rowles A, Mitchell DJ, Rasmussen AD. 2015. Detection of mild and reversible neurohistopathological changes in the brain of juvenile (preweaned) beagle dogs treated with vigabatrin for up to 91 days. Toxicol Pathol 43(7):1015-24; doi: 10.1177/0192623315591838 . PMID: 26157036.
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Publication: Manuscripts
/ Topics: toxicokinetics
Wikoff D , Doepker C , Welsh B, Urban J , Henderson R , Britt J , Harvey S , Goldberger J, Myers E, O’Brien C, Peck J, Lieberman H, Weaver C, Tenebein M. 2015. Systematic review of the adverse bone and calcium balance effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children. PROSPERO 2015:CRD42015026609 Available from http://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42015026609 (Systematic Review Protocol Registration)
Publication: Protocol Registrations
/ Topics: food safety , Food science , Systematic Review
Wikoff D , Doepker C , Welsh B, Urban J , Henderson R , Brorby G , Britt J , Harvey S , et al. 2015. Systematic review of the adverse cardiovascular effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children. PROSPERO 2015:CRD42015026673. Available from https://www.crd.york.ac.uk/PROSPERO/view/CRD42015026673 (Systematic Review Protocol Registration)
Publication: Protocol Registrations
/ Topics: Food science , Systematic Review
Ulrich K . Inhalation toxicology – Regulatory aspects for pharmaceuticals. Presentation to In Vitro Toxicology Society Annual Meeting, Birmingham, UK, 2015.
Publication: Abstracts and Presentations
/ Topics: inhalation toxicology , pharmacology , regulatory toxicology
Ulrich K . Requirements of nonclinical inhalation studies for clinical development and registration. Presentation to British Society of Toxicological Pathologists (BSTP) — Continuing Education Symposium 4, Department of Pathology, Cambridge, UK, 2015.
Publication: Abstracts and Presentations
/ Topics: inhalation toxicology
Greene N , Pennie W. 2015. Computational toxicology: Friend or foe? Toxicol Res 4(5):1159-1172; doi: 10.1039/c5tx00055f .
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Publication: Manuscripts
/ Topics: computational toxicology
Mackay CE, Vivanco SN , Reinhardt TE, McClure S, Vercellone J. 2015. Real-time monitoring and assessment of thermal and toxicological risk associated with fire retardant textiles in a full-size simulation of an engulfment flash fire. Fire Technol 51(5):1167–1193; doi: 10.1007/s10694-015-0456-3 .
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Publication: Manuscripts
/ Topics: flame retardants , risk assessment
Kelsh MA , Chia VM. Historical comparator studies: Strengths, limitations, and analytical considerations in using historical pooled clinical data for evaluating efficacy and safety of new therapies. Presented at International Conference on Pharmacoepidemiology and Therapeutic Risk Management (ICPE) Boston, MA, August 25, 2015.
Publication: Abstracts and Presentations
/ Topics: Epidemiology
Suh M , Mittal L , Hirsch S, Valdes R, Bartlett C, Rohr A, Proctor D. 2015. Lung cancer risk in chromate production workers exposed to hexavalent chromium. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.
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