Eichenbaum G, Yang K, Gebremichael Y, Howell BA, Murray FJ, Jacobson-Kram D, Jaeschke H, Kuffner E, Gelotte CK, Lai JCK, Wikoff D , Atillasoy E. 2020. Application of the DILIsym® Quantitative Systems Toxicology drug-induced liver injury model to evaluate the carcinogenic hazard potential of acetaminophen. Regul Toxicol Pharmacol 118(Dec):104788; doi: 10.1016/j.yrtph.2020.104788 . PMID: 33153971.
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Publication: Manuscripts
/ Topics: carcinogens , modeling
Cohen SS, Roger VL, Weston SA, Jiang R, Movva N , Yusuf AA, Chamberlain AM. 2020. Evaluation of claims-based computable phenotypes to identify heart failure patients with preserved ejection fraction. Pharmacol Res Persp 8(6):e00676; doi: 10.1002/prp2.676 . PMID: 33124771.
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Publication: Manuscripts
/ Topics: Epidemiology , Health Economics and Outcomes Research (HEOR)
Houben GF, Baumert JL, Blom WM, Kruizinga AG, Meima MY, Remington BC, Wheeler MW , Westerhout J, Taylor SL. 2020. Full range of population eliciting dose values for 14 priority allergenic foods and recommendations for use in risk characterization. Food Chem Toxicol 146(Dec)111831; doi: 10.1016/j.fct.2020.111831 . PMCID: PMC7864389.
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Publication: Manuscripts
/ Topics: dose-response , Food science , risk analysis , risk assessment
Shoskes A, Migdady I, Rice C, Hassett C, Deshpande A, Price C , et al. 2020. Brain injury is more common in venoarterial extracorporeal membrane oxygenation than venovenous extracorporeal membrane oxygenation: A systematic review and meta-analysis. Crit Care Med 48(12):1799–1808; https://doi.org/10.1097/CCM.0000000000004618 .
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Publication: Manuscripts
/ Topics: meta-analysis , Systematic Review
Mallack EJ, Turk BR, Yan H, Price C , Demetres M, Moser AB, et al. 2020. MRI surveillance of boys with X-linked adrenoleukodystrophy identified by newborn screening: Meta-analysis and consensus guidelines. J Inherit Metab Dis 44(3):728–739; https://doi.org/10.1002/jimd.12356 .
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Publication: Manuscripts
/ Topics: meta-analysis
Levin-Sparenberg E, Bylsma LC , Lowe K, Sangare L, Fryzek JP, Alexander DD. 2020. A systematic literature review and meta-analysis describing the prevalence of KRAS, NRAS, and BRAF gene mutations in metastatic colorectal cancer. Gastroenterol Res 13(5):184–198; doi: 10.14740/gr1167 .
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Publication: Manuscripts
/ Topics: Cancer , Epidemiology , Systematic Review
Cohen S, Reichert H , Kansal AR, Chung KC. Improved efficiency of cancer screening with multi-cancer early detection test. International Society for Pharmacoeconomics and Outcomes Research, Inc. (ISPOR) Virtual Conference, May 2020.
Publication: Abstracts and Presentations
/ Topics: Cancer , Epidemiology
Cekola P, Henrickson A, Cohen SS, Reichert H , Ararujo Torres K, Hulsey A. Growth and tolerance with an amino acid formula at a children’s center: A two-year retrospective review. Poster presented to North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN), November 2020.
Publication: Abstracts and Presentations
/ Topics: Epidemiology
Li S, Liu J, Gong T, Guo H, Gawade PL, Kelsh MA , et al. 2020. Duration of short-acting granulocyte colony-stimulating factor for primary prophylaxis and risk of neutropenia-related hospitalization in older patients with cancer. J Geriatr Oncol 11(8):1309–1315; doi: 10.1016/j.jgo.2020.06.018 . PMID: 32624415.
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Publication: Manuscripts
/ Topics: Cancer
Ravandi F, Pierce S, Garcia-Manero G, Kadia T, Jabbour E, Borthakur G, … Kelsh M , et al. 2020. Salvage therapy outcomes in a historical cohort of patients with relapsed or refractory acute myeloid leukemia. Clin Lymphoma Myeloma Leuk 20(11):e871–e882.
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Publication: Manuscripts
/ Topics: Cancer , Epidemiology
Thompson CM , Gentry R, Fitch S , Lu K, Clewell HJ. 2020. An updated mode of action and human relevance framework evaluation for formaldehyde-related nasal tumors. Crit Rev Toxicol 50(10):919–952; doi: 10.1080/10408444.2020.1854679 . PMID: 33599198.
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Publication: Manuscripts
/ Topics: formaldehyde
Gentry R, Thompson CM , Franzen A , Salley J, Albertini R, Lu K, Greene T. 2020. Using mechanistic information to support evidence integration and synthesis: A case study with inhaled formaldehyde and leukemia. Crit Rev Toxicol 50(10):885–918; doi: 10.1080/10408444.2020.1854678 . PMID: 33538218.
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Publication: Manuscripts
/ Topics: Cancer , formaldehyde
Nelms MD, Karmaus AL, Patlewicz G . 2020. An evaluation of the performance of selected (Q)SARs/expert systems for predicting acute oral toxicity. Comput Toxicol 16(Nov):100135; doi: 10.1016/j.comtox.2020.100135 . PMID: 33163737.
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Publication: Manuscripts
/ Topics: modeling
Aerts M, Wheeler MW , Abrahantes JC. 2020. An extended and unified modeling framework for benchmark dose estimation for both continuous and binary data. Environmetrics 31(7):e2630; doi: 10.1002/env.2630 . PMCID: PMC9432821.
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Publication: Manuscripts
/ Topics: benchmark dose estimation (BMD) , dose-response
Bhat VS, Cohen SM, Gordon EB, Wood CE, Cullen JM, Harris MA, Proctor DM , Thompson CM . 2020. An adverse outcome pathway for small intestinal tumors in mice involving chronic cytotoxicity and regenerative hyperplasia: A case study with hexavalent chromium, captan, and folpet. Crit Rev Toxicol 50(8)685-706; doi: 10.1080/10408444.2020.1823934 .
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Publication: Manuscripts
/ Topics: chromium
Pradeep P, Patlewicz G , Pearce R, Wambaugh J, Wetmore B, Judson R. 2020. Using chemical structure information to develop predictive models for in vitro toxicokinetic parameters to inform high-throughput risk-assessment. Comput Toxicol 16(Nov):100136; doi: 10.1016/j.comtox.2020.100136 . PMID: 34124416.
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