2021 (96 POSTS)
Chappell GA, Heintz MM , Haws LC . 2021. Transcriptomic analyses of livers from mice exposed to 1,4-dioxane for up to 90 days to assess potential mode(s) of action underlying liver tumor development. Curr Res Toxicol 2:30–41; doi: 10.1016/j.crtox.2021.01.003 . PMID: 34345848.
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Topics: transcriptomics , VOCs
2020 (93 POSTS)
Wikoff D , Lewis JR, Erraguntla N, Franzen A , Foreman J. 2020. Facilitation of risk assessment with evidence-based methods — A framework for use of systematic mapping and systematic reviews in determining hazard, developing toxicity values, and characterizing uncertainty. Regul Toxicol Pharmacol 118:104790; doi: 10.1016/j.yrtph.2020.104790 . PMID: 33038430.
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Topics: risk assessment , Systematic Review
Purohit A, Jha R, Khalafallah AM, Price C , Rowan NR, Mukherjee D. 2020. Endoscopic endonasal versus transcranial approach to resection of olfactory groove meningiomas: A systematic review. Neurosurg Rev 43(6)1465-1471; doi: 10.1007/s10143-019-01193-2 . PMID: 31709465.
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Topics: Systematic Review
Eichenbaum G, Yang K, Gebremichael Y, Howell BA, Murray FJ, Jacobson-Kram D, Jaeschke H, Kuffner E, Gelotte CK, Lai JCK, Wikoff D , Atillasoy E. 2020. Application of the DILIsym® Quantitative Systems Toxicology drug-induced liver injury model to evaluate the carcinogenic hazard potential of acetaminophen. Regul Toxicol Pharmacol 118(Dec):104788; doi: 10.1016/j.yrtph.2020.104788 . PMID: 33153971.
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Topics: carcinogens , modeling
Cohen SS, Roger VL, Weston SA, Jiang R, Movva N , Yusuf AA, Chamberlain AM. 2020. Evaluation of claims-based computable phenotypes to identify heart failure patients with preserved ejection fraction. Pharmacol Res Persp 8(6):e00676; doi: 10.1002/prp2.676 . PMID: 33124771.
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Topics: Epidemiology , Health Economics and Outcomes Research (HEOR)
Houben GF, Baumert JL, Blom WM, Kruizinga AG, Meima MY, Remington BC, Wheeler MW , Westerhout J, Taylor SL. 2020. Full range of population eliciting dose values for 14 priority allergenic foods and recommendations for use in risk characterization. Food Chem Toxicol 146(Dec)111831; doi: 10.1016/j.fct.2020.111831 . PMID: 33166672.
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Topics: dose-response , Food science , risk analysis , risk assessment
Shoskes A, Migdady I, Rice C, Hassett C, Deshpande A, Price C , et al. 2020. Brain injury is more common in venoarterial extracorporeal membrane oxygenation than venovenous extracorporeal membrane oxygenation: A systematic review and meta-analysis. Crit Care Med 48(12):1799–1808; doi: 10.1097/CCM.0000000000004618 . PMID: 33031150.
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Topics: meta-analysis , Systematic Review
Li S, Liu J, Gong T, Guo H, Gawade PL, Kelsh MA , et al. 2020. Duration of short-acting granulocyte colony-stimulating factor for primary prophylaxis and risk of neutropenia-related hospitalization in older patients with cancer. J Geriatr Oncol 11(8):1309–1315; doi: 10.1016/j.jgo.2020.06.018 . PMID: 32624415.
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Topics: Cancer
Ravandi F, Pierce S, Garcia-Manero G, Kadia T, Jabbour E, Borthakur G, … Kelsh M , et al. 2020. Salvage therapy outcomes in a historical cohort of patients with relapsed or refractory acute myeloid leukemia. Clin Lymphoma Myeloma Leuk 20(11):e871–e882; doi: 10.1016/j.clml.2020.06.007 . PMID: 32792304.
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Topics: Cancer , Epidemiology
Thompson CM , Gentry R, Fitch S , Lu K, Clewell HJ. 2020. An updated mode of action and human relevance framework evaluation for formaldehyde-related nasal tumors. Crit Rev Toxicol 50(10):919–952; doi: 10.1080/10408444.2020.1854679 . PMID: 33599198.
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Topics: formaldehyde
Gentry R, Thompson CM , Franzen A , Salley J, Albertini R, Lu K, Greene T. 2020. Using mechanistic information to support evidence integration and synthesis: A case study with inhaled formaldehyde and leukemia. Crit Rev Toxicol 50(10):885–918; doi: 10.1080/10408444.2020.1854678 . PMID: 33538218.
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Topics: Cancer , formaldehyde
Nelms MD, Karmaus AL, Patlewicz G . 2020. An evaluation of the performance of selected (Q)SARs/expert systems for predicting acute oral toxicity. Comput Toxicol 16(Nov):100135; doi: 10.1016/j.comtox.2020.100135 . PMID: 33163737.
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Topics: modeling
Aerts M, Wheeler MW , Abrahantes JC. 2020. An extended and unified modeling framework for benchmark dose estimation for both continuous and binary data. Environmetrics 31(7):e2630; doi: 10.1002/env.2630 . PMID: 36052215.
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Topics: benchmark dose estimation (BMD) , dose-response
Brusa V, Costa M, Padola NL, Etcheverria A, Sampedro F , Fernandez PS, Leotta GA, Signorini ML. 2020. Quantitative risk assessment of haemolytic uremic syndrome associated with beef consumption in Argentina. PLoS One 15(11): e0242317; doi: 10.1371/journal.pone.0242317 . PMID: 33186398.
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Topics: Food science , risk assessment
Pradeep P, Patlewicz G , Pearce R, Wambaugh J, Wetmore B, Judson R. 2020. Using chemical structure information to develop predictive models for in vitro toxicokinetic parameters to inform high-throughput risk-assessment. Comput Toxicol 16(Nov):100136; doi: 10.1016/j.comtox.2020.100136 . PMID: 34124416.
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Topics: risk assessment , toxicokinetics
Revollo JR, Dad A, Pearce MG, Mittelstaedt RA, Casildo A, Lapidus RG, Robison TW , Dobrovolsky VN. 2020. CD59-deficient bone marrow erythroid cells from rats treated with procarbazine and propyl-nitrosourea have mutations in the Pig-a gene. Environ Mol Mutagen 61(8):797-806; doi: 10.1002/em.22402 . PMID: 32729949.
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Topics: flow cytometry
Thompson CM , Donahue DA, Hobbs C, Costecalde Y, Franzen A , Suh M , Proctor DM , Harris MA. 2020. Exposure to environmentally-relevant concentrations of hexavalent chromium does not induce ovarian toxicity in mice. Regul Toxicol Pharmacol 116(Oct):104729; doi: 10.1016/j.yrtph.2020.104729 . PMID: 32652207.
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Topics: chromium , Environmental Science , Metals
Saldanha G, Ording AG, Bylsma LC , Darvalics B, Solis D, Tang JY, Sorensen HT, Fryzek J. 2020. High frequency basal cell carcinoma (BCC) in Danish patients: Prevalence and consistency. J Eur Acad Dermatol Venereol 34(10):e646-e648; doi: 10.1111/jdv.16512 . PMID: 32314479.
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Topics: Cancer
Buerger AN , Dillon DT, Schmidt J, Yang T, Zubcevic J, Martyniuk CJ, et al. 2020. Gastrointestinal dysbiosis following diethylhexyl phthalate exposure in zebrafish (Danio rerio ): Altered microbial diversity, functionality and network connectivity. Environ Pollut 265(Pt B-Oct):114496; doi: 10.1016/j.envpol.2020.11449 . PMID: 32806437.
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Topics: phthalates
Nelms MD, Patlewicz G . 2020. Derivation of new threshold of toxicological concern values for exposure via inhalation for environmentally-relevant chemicals. Front Toxicol 2:580347; doi: 10.3389/ftox.2020.580347 . PMID: 35296122.
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