2025 (60 POSTS)
Duong T, Haselkorn T, Miller B, Coats J, Jensen I , Ward E, Wood M, Graham RJ, Servais L. 2025. A real-world analysis of the impact of X-linked myotubular myopathy on caregivers in the United States. Orphanet J Rare Dis 20(1):224. doi: 10.1186/s13023-025-03583-w . PMID: 40355957.
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Topics: Health Economics and Outcomes Research (HEOR)
Crincoli CM, van de Ligt JLG, Eapen AK. Pavel AT, Hanlon PR, Almond-Abbate K, Haugabrooks E,… Henderson RG . 2025. A tool to support food substance safety evaluations in the United States. Regul Toxicol Pharmacol 161(Sept):105838; doi: 10.1016/j.yrtph.2025.105838 . PMID: 40324559.
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Topics: food additives , food safety , Food science , risk assessment
Rogers JM, Heintz MM, Haws LC . 2025. Reproductive and developmental toxicity screen (OECD TG 421) and extended one generation reproductive toxicity study (OECD TG 443) of decahydronaphthalene in Sprague Dawley rats. Regul Toxicol Pharmacol 160(Aug):105829; doi: 10.1016/j.yrtph.2025.105829 . PMID: 40222475.
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Topics: reproductive toxicology
Heintz MM , Buerger AN, Haws LC , Cullen JM, East AW, Thompson CM . 2025. Comparison of phenotypic and transcriptomic profiles between HFPO-DA and prototypical PPARα , PPARγ , and cytotoxic agents in wild-type and Pparα -null mouse livers. Toxicol Sci 206(1):183-201; doi: 10.1093/toxsci/kfaf049 . PMID: 40216583.
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Topics: mode of action , transcriptomics
Lipke L, Price C . 2025. Rethinking systematic review assignment design in graduate health science education from librarians’ perspectives. Hypoth: Res J Health Info Prof 37(1); doi: 10.18060/28463 .
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Topics: Systematic Review
Nordyke RJ , Motyka J, Patterson JA. 2025. The association of 340B program drug margins with covered entity characteristics. Inquiry 62(Jan-Dec):469580251324051; doi: 10.1177/00469580251234051 . PMID: 4012322.
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Topics: Health Economics and Outcomes Research (HEOR)
Hanser T, Ahlberg E, Amberg A, Anger LT, Barber C, Brennan RJ, Brigo A,…, Greene N , et al. 2025. Data-driven federated learning in drug discovery with knowledge distillation. Nat Mach Intell 7(Mar):423–436; doi: 10.1038/s42256-025-00991-2 .
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Topics: computational toxicology , NAMs
Wikoff DS, Vincent MJ, Heintz MM, Pastula ST, Reichert H, Klaren WD, Haws LC . 2025. Application of a quantitative uncertainty assessment to develop ranges of plausible toxicity values when using observational data in risk assessment: A case study examining associations between PFOA and PFOS exposures and vaccine response. Toxicol Sci 204(1):96-115; doi: 10.1093/toxsci/kfae152 . PMID: 39792025.
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Topics: PFAS , risk assessment , Systematic Review
Nguyen HVM, Cabello E, Dyer D, Fender C , Garcia-Jaramillo M, Hord NG, Austad S, Richardson A, Unnikrishnan A. 2025. Age, sex, and mitochrondrial-haplotype influence gut microbiome composition and metabolites in a genetically diverse rat. Aging 17(2):524-549; doi: 10.18632/aging.206211 . PMID: 40015964.
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Topics: metabolites
Lea IA , Feifarek D, Mihalchik A, Heintz M, Haws L, Nyambego H, Goyak K, Palermo C, Borghoff SJ . 2025. Evaluation of the endocrine disrupting potential of Di-isodecyl phthalate. Curr Res Toxicol 8:100221; doi: 10.1016/j.crtox.2025.100221 . PMID: 40041033.
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Topics: phthalates
Kramer A , Vivanco S , Bare J , Panko J . 2025. Analysis of EPA air toxics monitoring data and tools for use in general population exposure assessments: Using acrylonitrile as a case study. J Air Waste Manag Assoc 75(3)181-197; doi: 10.1080/10962247.2024.2438793 . PMID: 39660961.
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Topics: Air Quality , Exposure Assessment
Pastula ST , Bylsma LC , Rege SV, Lewis RJ, Movva N . 2025. Scoping review of indices to measure a community’s health status. Popul Health Manag 28(1):37-49; doi: 10.1089/pop.2024.0138 . PMID: 39558762.
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Topics: community health , Epidemiology , scoping review
Verwiel A, Rish W . 2025. Multidisciplinary perspectives on cumulative impact assessment for vulnerable communities: Expert elicitation using a Delphi method. Integr Environ Assess Manag 21(2):301-313; doi: 10.1093/inteam/vjae051 . PMID: 39881570.
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Topics: Air Quality , risk assessment
Seal S, Trapotsi MA, Spjuth O, Singh S, Carreras-Puigvert J, Greene N , Bender A, Carpenter AE. 2025. Cell painting: A decade of discovery and innovation in cellular imaging. Nat Meth 22(2):254-268 ; doi: 10.1038/s41592-024-02528-8 . PMID: 39639168.
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Topics: computational toxicology
Lagiakos HR, Zou Y, Igawa H, Therrien E, Lawrenz M, Kato M, Svensson M,…, Dingley K , et al. 2025. In silico enabled discovery of KAI-11101, a preclinical DLK inhibitor for the treatment of neurodegenerative disease and neuronal injury. J Med Chem 68(3):2720-2741; doi: 10.1021/acs.jmedchem.4c02074 . PMID: 39670820.
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Topics: drug development
Payton A, Hickman, Chappel J, Roell KR, Koval LA, Eaves LA, Chou CK,…, Patlewicz G , et al. 2025. TAME 2.0: Expanding and improving online data science training for environmental health research. Front Toxicol 7(Feb 12):1535098; doi: 10.3389/ftox.2025.1535098 . PMID: 40012886.
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Topics: Exposure Assessment
Borghoff SJ , Rivera B, Fitch S , Buerger AN , Choksi N , Franzen A , Vincent MJ , Covington T , Bus J, Rushton E, Lea IA . 2025. Systematic evaluation of the evidence base on methyl tert -butyl ether supporting a lack of concern for carcinogenic hazard in human based on animal cancer studies and mechanistic data. Curr Res Toxicol 8:100224; doi: 10.1016/j.crtox.2025.100224 . PMID: 40084233.
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Topics: Cancer , carcinogens , MTBE , risk assessment
O’Brien J, Mitchell C, Auerbach S, Doonan L, Ewald J, Everett L, Faranda A,.., Wheeler MW , et al. 2025. Bioinformatic workflows for deriving transcriptomic points of departure: Current status, data gaps, and research priorities. Toxicol Sci 203(2):147-159; doi: 10.1093/toxsci/kfae145 . PMID: 39499193.
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Topics: transcriptomics
Rogers JM, Buerger AN , Heintz MM , Palermo CM, Haws LC, Lea IA . 2025. Evaluation of a hypothesized Sertoli cell-based adverse outcome pathway for effects of diisononyl phthalate on the developing testis. Curr Res Toxicol 8:100219; doi: 10.1016/j.crtox.2025.100219 . PMID: 40123861.
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