2017 (63 POSTS)
Kirman CR, Suh M, Proctor DM , Hays SM. 2017. Improved physiologically based pharmacokinetic model for oral exposures to chromium in mice, rats, and humans to address temporal variation and sensitive populations. Toxicol Appl Pharmacol 325(15 June):9-17; doi: 10.1016/j.taap.2017.03.023 . PMID: 28389273.
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Topics: chromium , modeling , PBPK/PBDE , pharmacokinetics
Mease K , Kimzey A , Lansita J. 2017. Biomarkers for nonclinical infusion reactions in marketed biotherapeutics and considerations for study design. Curr Opin Toxicol 4(June):1–15; doi: 10.1016/j.cotox.2017.03.005 . PMID: 29658009.
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Topics: biomarkers
Judson RS, Martin M, Patlewicz G , Wood CE. 2017. Retrospective mining of toxicology data to discover multispecies and chemical class effects: Anemia as a case study. Regul Toxicol Pharmacol 86(June):74-92; doi: 10.1016/j.yrtph.2017.02.015 . PMID: 28242142.
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Topics: modeling
Wang Y, Villalta PW, Peng L, Dingley KH , Malfatti MA, Turteltaub KW, Turesky RJ. 2017. Mass spectrometric characterization of an acid-labile adduct formed with 2-amino-1-methyl-phenylimidazo[4,5-b]pyridine and albumin in humans. Chem Res Toxicol 30(2):705–714; doi: 10.1021/acs.chemrestox.6b00426 . PMID: 27984695.
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Topics: carcinogens
Harper BH, Wang L, Zhu C, Kar NF, Li B, Moyes CR, … Dingley K , et al. 2017. Investigation of piperazine benzamides as human β3 adrenergic receptor agonists for the treatment of overactive bladder. Bioorg Med Chem Lett 27(4):1094–1098; doi: 10.1016/j.bmcl.2016.12.033 . PMID: 28089699.
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Topics: pharmacokinetics
Zhu C, Wang L, Zhu Y, Guo ZZ, Liu P, Hu Z, … Dingley KH , et al. 2017. Discovery of phenyl acetamides as potent and selective GPR119 agonists. Bioorg Med Chem Lett 27(5):1124–1128; doi: 10.1016/j.bmcl.2017.01.091 . PMID: 28185720.
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Topics: pharmacokinetics
Pandalai SP, Wheeler MW , Lu M-L. 2017. Non-chemical risk assessment for lifting and low back pain based on Bayesian threshold models. Saf Health Work 8(2):206-11; doi: 10.1016/j.shaw.2016.10.001 . PMCID: PMC5447412.
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Topics: Bayesian modeling , Occupational , risk assessment
Finley B , Scott PK, Glynn ME, Paustenbach D, Donovan E, Thuett KA. 2017. Chromium speciation in the blood of metal-on-metal hip implant patients. Environ Toxicol Chem 99(1):48–64; doi: 10.1080/02772248.2016.1148904 .
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Topics: chromium , Exposure Assessment , Metals
Kovochich M, Fung ES, Donovan E, Unice KM, Paustenbach DJ, Finley BL . 2017. Characterization of wear debris from metal-on-metal hip implants during normal wear versus edge-loading conditions. J Biomed Mater Res 106(3):986–996; doi: 10.1002/jbm.b.33902 .
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Topics: Metals
Fung ES, Monnot A, Kovochich M, Unice KM, Tvermoes BE, Galbraith D, Finley BL , Paustenbach DJ. 2017. Characteristics of cobalt-related cardiomyopathy in metal hip implant patients: An evaluation of 15 published reports. Cardiovascul Toxicol 18(3):206–220; doi: 10.1007/s12012-017-9433-z .
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Topics: cobalt
Finley BL , Benson SM, Marsh GM. 2017. Cosmetic talc as a risk factor for pleural mesothelioma: A weight of evidence valuation of the epidemiology. Inhal Toxicol 29(4):179–185; doi: 10.1080/08958378.2017.1336187 .
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Topics: Cancer , Epidemiology , talc
Mullins M, Jiang X , Bylsma LC , Fryzek JP, Reichert H , Chen EC, Kummar S, Rosenthal A. 2017. Cold agglutinin disease burden: A longitudinal analysis of anemia, medications, transfusions, and healthcare utilization. Blood Adv 1(13):839-848; doi: 10.1182/bloodadvances.2017004390 . PMID: 29296728.
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Topics: Cancer , Epidemiology
Borghoff SJ , Ring C, Banton M, Leavens TL. 2017. Physiologically based pharmacokinetic model for ethyl tertiary-butyl ether and tertiary-butyl alcohol in rats: Contribution of binding to a2u-globulin in male rats and high-exposure nonlinear kinetics to toxicity and cancer outcomes. J Appl Toxicol 37(5):621-640; doi: 10.1002/jat.3412 . PMID: 27885692.
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Topics: modeling , pharmacokinetics
Miller LM, Lampe JW, Newton KM, Gundersen G, Fuller S, Reed SD, Frankenfeld CL . 2017. Being overweight or obese is associated with harboring a gut microbial community not capable of metabolizing the soy isoflavone daidzein to O-desmethylangolensin in soy-consuming peri- and post-menopausal women. Maturitas 99(May):37–42; doi: 10.1016/j.maturitas.2017.02.006 . PMID: 28364866.
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