2022 (178 POSTS)
Heintz MM , Chappell GA, Thompson CM , Haws LC . 2022. Evaluation of transcriptomic responses in livers of mice exposed to the short-chain PFAS compound HFPO-DA. Front Toxicol 4(Jun 27):937168; doi: 10.3389/ftox.2022.937168 . PMID: 35832492.
View Abstract
Publication: Manuscripts
/ Topics: PFAS , transcriptomics
Gloekler LE, de Gandiaga EJ, Binczewski NR, Steimel KG, Massarsky A, Kozal J, Vincent M , et al. 2022. Evaluation of the safety and efficacy of hand sanitizer products marketed to children available during the COVID-19 pandemic. Int J Env Res Pub Health 19(21):14424; doi: 10.3390/ijerph19211442 . PMID: 36361303.
View Abstract
Publication: Manuscripts
/ Topics: consumer products , COVID-19
Goyak KO, Sarang SS, Franzen A , Borghoff SJ , Ryman-Rasumssen JP. 2022. Adverse outcome pathway (AOP): α2u-globulin nephropathy and kidney tumors in male rats. Crit Rev Toxicol 52(5):345-357; doi: 10.1080/10408444.2022.2082269 . PMID: 35862579.
View Abstract
Publication: Manuscripts
/ Topics: Adverse outcome pathways (AOPs)
Foster MJ, Patlewicz G , Shah I, Haggard DE, Judson RS, Paul Friedman K. 2022. Evaluating structure-based activity in a high throughput assay for steroid biosynthesis. Comput Toxicol 24(Nov):100245; doi: 10.1016/j.comtox.2022.100245 . PMID: 37841081.
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Publication: Manuscripts
/ Topics: NAMs
Frankenfeld CL , Maskarinec G, Franke AA. 2022. Metabolomics profiles of premenopausal women are different based on O-desmethylangolensin metabotype. Brit J Nutr 128(8):1490–1498; doi: 10.1017/S0007114521004463 . PMID: 34763731.
View Abstract
Publication: Manuscripts
/ Topics: metabolites
Knotts T, Diokno R, Husfeld C, Weinberger D, Mease K , Wollowitz S, Kramer S, Donovan J. Vocacapsaicin (formerly CA-008): A water-soluble prodrug for rapid release of capsaicin for the treatment of postsurgical pain. Presentation to American Association of Pharmaceutical Scientists, AAPS PHARMSCI 360, Boston, MA, October 2022.
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Publication: Abstracts and Presentations
/ Topics: drug interactions
Suh M , Cloud M, Balasubramanian A, Movva N , Fryzek J, Cohen S. 2022. A systematic literature review (SLR) of MTAP deletions in multiple solid and hematologic cancers. PROSPERO 2022 CRD42022354037 .
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Publication: Protocol Registrations
/ Topics: Cancer , Epidemiology , Systematic Review
Knotts T, Mease K , Sangameswaran L, Felx M, Kramer S, Donovan J. 2022. Pharmacokinetics and local tissue response to local instillation of vocacapsaicin, a novel capsaicin prodrug, in rat and rabbit osteotomy models. J Orthop Res 40(10):2281-2293; doi: 10.1002/jor.25271 . PMID: 35128722.
View Abstract
Publication: Manuscripts
/ Topics: drug development , pharmacokinetics
Moyer H , Vergara, L, Valdiviezo A, Sakolish C, Chiu WA, Stephan C, Rusyn I. Investigation of intestinal permeability in three microphysiological systems. Texas A&M University Superfund External Advisory Board Meeting, College Station, TX, October 2022.
Publication: Abstracts and Presentations
/ Topics: modeling
Schaefer HR , Flannery BM, Crosby L, Jones-Dominic OE, Punzalan C, Middleton K. 2022. A systematic review of adverse health effects associated with oral cadmium exposure. Regul Toxicol Pharmacol 134(Oct):105243; doi: 10.1016/j.yrtph.2022.105243 . PMID: 35981600.
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Publication: Manuscripts
/ Topics: cadmium , Exposure Assessment , Systematic Review
Frankenfeld CL . Biostatistical approaches in gut microbiome research. Presentation for American Society of Nutrition-Institute for the Advancement of Food and Nutrition Science Collaborative Session “Sample Collection, Preservation, and Data Analysis in Gut Microbiome Research: Current Methods and Potential Impact on Results,” October 13, 2022.
Publication: Abstracts and Presentations
/ Topics: Epidemiology
Patlewicz G , Richard A, Williams A, Judson R, Thomas R. Towards reproducible structure-based chemical categories for PFAS to inform and evaluate toxicity and toxicokinetic testing. American Society for Cellular and Computation Toxicology 11th Annual Meeting, Chapel Hill, NC, October 2022.
Publication: Abstracts and Presentations
/ Topics: PFAS
Patlewicz G , Shah I. Towards systematic read-across using Generalised Read-Across (GenRA). American Society for Cellular and Computation Toxicology 11th Annual Meeting, Chapel Hill, NC, October 2022.
Publication: Abstracts and Presentations
/ Topics: read-across
Nicolas CI, Linakis MW, Minto MS, Mansouri K, Clewell RA, Yoon M, Wambaugh JF, Patlewicz G , et al. 2022. Estimating provisional margins of exposure for data poor chemicals using high throughput computational methods. Front Pharmacol 13(Oct 7):980747; doi: 10.3389/fphar.2022.980747 . PMID: 36278238.
View Abstract
Publication: Manuscripts
/ Topics: computational toxicology
Carstens K, Carpenter A, FreudenrichT, Wallace K, Choo S, Patlewicz G , et al. Evaluation of per- and poly fluoroalkyl substances (PFAS) in vitro toxicity testing for developmental neurotoxicity. American Society for Cellular and Computation Toxicology 11th Annual Meeting, Chapel Hill, NC, October 2022.
Publication: Abstracts and Presentations
/ Topics: PFAS
Hagan B, Patlewicz G , Shah I. Metabolic similarity in read-across prediction: A case study in using graph kernels and predicted metabolism information. American Society for Cellular and Computation Toxicology 11th Annual Meeting, Chapel Hill, NC, October 2022
Publication: Abstracts and Presentations
/ Topics: read-across
Gupta N, Patel HD, Taylor J, Borin JF, Jacobsohn K,…, Price C , et al. 2022. Systematic review of the impact of a plant-based diet on prostate cancer incidence and outcomes. Prostate Cancer Prostatic Dis 25(3):444–452; doi: 10.1038/s41391-022-00553-2 . PMID: 35790788.
View Abstract
Publication: Manuscripts
/ Topics: Cancer , Systematic Review
Habib A, Sacks NC , Cool C, Durgapal S, Hughes T, Hernandez J, Phillips G. Trends in hospital admissions and readmissions for patients with MG from U.S. national research databases. Poster presentation, American Association of Neuromuscular and Electrodiagnostic Medicine (AANEM) Annual Meeting, September 2022.