2022 (182 POSTS)
Patlewicz G , Richard AM, Williams AJ, Judson RS, Thomas RS. 2022. Towards reproducible structure-based chemical categories for PFAS to inform and evaluate toxicity and toxicokinetic testing. Comput Toxicol 24(Nov):100250; doi: 10.1016/j.comtox.2022.100250 . PMID: 36969381.
View Abstract
Publication: Manuscripts
/ Topics: NAMs , PFAS
Cohen SS, Bylsma LC, Movva N , Alexander DD. 2022. Theoretical attributable risk analysis and Disability Adjusted Life Years (DALYs) based on increased dairy consumption. BMC Public Health 22(1):1625; doi: 10.1186/s12889-022-14042-7 . PMID: 36030208.
View Abstract
Publication: Manuscripts
/ Topics: Food science , risk analysis
Heintz MM , Chappell GA, Thompson CM , Haws LC . 2022. Evaluation of transcriptomic responses in livers of mice exposed to the short-chain PFAS compound HFPO-DA. Front Toxicol 4(Jun 27):937168; doi: 10.3389/ftox.2022.937168 . PMID: 35832492.
View Abstract
Publication: Manuscripts
/ Topics: PFAS , transcriptomics
Gloekler LE, de Gandiaga EJ, Binczewski NR, Steimel KG, Massarsky A, Kozal J, Vincent M , et al. 2022. Evaluation of the safety and efficacy of hand sanitizer products marketed to children available during the COVID-19 pandemic. Int J Env Res Pub Health 19(21):14424; doi: 10.3390/ijerph19211442 . PMID: 36361303.
View Abstract
Publication: Manuscripts
/ Topics: consumer products , COVID-19
Goyak KO, Sarang SS, Franzen A , Borghoff SJ , Ryman-Rasumssen JP. 2022. Adverse outcome pathway (AOP): α2u-globulin nephropathy and kidney tumors in male rats. Crit Rev Toxicol 52(5):345-357; doi: 10.1080/10408444.2022.2082269 . PMID: 35862579.
View Abstract
Publication: Manuscripts
/ Topics: Adverse outcome pathways (AOPs)
Foster MJ, Patlewicz G , Shah I, Haggard DE, Judson RS, Paul Friedman K. 2022. Evaluating structure-based activity in a high throughput assay for steroid biosynthesis. Comput Toxicol 24(Nov):100245; doi: 10.1016/j.comtox.2022.100245 . PMID: 37841081.
View Abstract
Publication: Manuscripts
/ Topics: NAMs
Frankenfeld CL , Maskarinec G, Franke AA. 2022. Metabolomics profiles of premenopausal women are different based on O-desmethylangolensin metabotype. Brit J Nutr 128(8):1490–1498; doi: 10.1017/S0007114521004463 . PMID: 34763731.
View Abstract
Publication: Manuscripts
/ Topics: metabolites
Knotts T, Diokno R, Husfeld C, Weinberger D, Mease K , Wollowitz S, Kramer S, Donovan J. Vocacapsaicin (formerly CA-008): A water-soluble prodrug for rapid release of capsaicin for the treatment of postsurgical pain. Presentation to American Association of Pharmaceutical Scientists, AAPS PHARMSCI 360, Boston, MA, October 2022.
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Publication: Abstracts and Presentations
/ Topics: drug interactions
Suh M , Cloud M, Balasubramanian A, Movva N , Fryzek J, Cohen S. 2022. A systematic literature review (SLR) of MTAP deletions in multiple solid and hematologic cancers. PROSPERO 2022 CRD42022354037 .
View Abstract
Publication: Protocol Registrations
/ Topics: Cancer , Epidemiology , Systematic Review
Knotts T, Mease K , Sangameswaran L, Felx M, Kramer S, Donovan J. 2022. Pharmacokinetics and local tissue response to local instillation of vocacapsaicin, a novel capsaicin prodrug, in rat and rabbit osteotomy models. J Orthop Res 40(10):2281-2293; doi: 10.1002/jor.25271 . PMID: 35128722.
View Abstract
Publication: Manuscripts
/ Topics: drug development , pharmacokinetics
Moyer H , Vergara, L, Valdiviezo A, Sakolish C, Chiu WA, Stephan C, Rusyn I. Investigation of intestinal permeability in three microphysiological systems. Texas A&M University Superfund External Advisory Board Meeting, College Station, TX, October 2022.
Publication: Abstracts and Presentations
/ Topics: modeling
Bartlett C , Heine L. Stay ahead of regulations and trends. ChemWatch Cosmetic Regulatory Summit, Washington, DC, October 2022.
Publication: Abstracts and Presentations
/ Topics: regulatory toxicology
Schaefer HR , Flannery BM, Crosby L, Jones-Dominic OE, Punzalan C, Middleton K. 2022. A systematic review of adverse health effects associated with oral cadmium exposure. Regul Toxicol Pharmacol 134(Oct):105243; doi: 10.1016/j.yrtph.2022.105243 . PMID: 35981600.
View Abstract
Publication: Manuscripts
/ Topics: cadmium , Exposure Assessment , Systematic Review
Frankenfeld CL . Biostatistical approaches in gut microbiome research. Presentation for American Society of Nutrition-Institute for the Advancement of Food and Nutrition Science Collaborative Session “Sample Collection, Preservation, and Data Analysis in Gut Microbiome Research: Current Methods and Potential Impact on Results,” October 13, 2022.
Publication: Abstracts and Presentations
/ Topics: Epidemiology
Patlewicz G , Richard A, Williams A, Judson R, Thomas R. Towards reproducible structure-based chemical categories for PFAS to inform and evaluate toxicity and toxicokinetic testing. American Society for Cellular and Computation Toxicology 11th Annual Meeting, Chapel Hill, NC, October 2022.
Publication: Abstracts and Presentations
/ Topics: PFAS
Patlewicz G , Shah I. Towards systematic read-across using Generalised Read-Across (GenRA). American Society for Cellular and Computation Toxicology 11th Annual Meeting, Chapel Hill, NC, October 2022.
Publication: Abstracts and Presentations
/ Topics: read-across
Nicolas CI, Linakis MW, Minto MS, Mansouri K, Clewell RA, Yoon M, Wambaugh JF, Patlewicz G , et al. 2022. Estimating provisional margins of exposure for data poor chemicals using high throughput computational methods. Front Pharmacol 13(Oct 7):980747; doi: 10.3389/fphar.2022.980747 . PMID: 36278238.
View Abstract
Publication: Manuscripts
/ Topics: computational toxicology
Carstens K, Carpenter A, FreudenrichT, Wallace K, Choo S, Patlewicz G , et al. Evaluation of per- and poly fluoroalkyl substances (PFAS) in vitro toxicity testing for developmental neurotoxicity. American Society for Cellular and Computation Toxicology 11th Annual Meeting, Chapel Hill, NC, October 2022.
Publication: Abstracts and Presentations
/ Topics: PFAS
Hagan B, Patlewicz G , Shah I. Metabolic similarity in read-across prediction: A case study in using graph kernels and predicted metabolism information. American Society for Cellular and Computation Toxicology 11th Annual Meeting, Chapel Hill, NC, October 2022