2025 (129 POSTS)
Sakolish C, Moyer H , Barlow N, Roe H, Tsai H, Ford L, Bajaj P, Villenave R, et al. Microphysiological systems as predictive tools for kidney nephrotoxicants: A comparison across four platforms. Abstract 3216, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025 .
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Publication: Abstracts and Presentations
/ Topics: pharmacokinetics
Moyer H , Vergara L, Sakolish C, Stephan C, Barlow N, Roe H, Hewitt P, Villenave R, Rusyn I. Comparative analysis of drug permeability and toxicity in intestinal segment-specific membrane-based barrier model using Caco-2 and human jejunal and duodenal enteroid-derived cells. Abstract 3217, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025 .
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Publication: Abstracts and Presentations
/ Topics: modeling , pharmacokinetics
Hanser T, Ahlberg E, Amberg A, Anger LT, Barber C, Brennan RJ, Brigo A,…, Greene N , et al. 2025. Data-driven federated learning in drug discovery with knowledge distillation. Nat Mach Intell 7(Mar):423–436; doi: 10.1038/s42256-025-00991-2 .
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Publication: Manuscripts
/ Topics: computational toxicology , NAMs
Bogar L, Yale K , Allen L, Burns A . Airborne silica from bentonite clay cat litter: An evaluation of potential non-occupational exposure and respiratory health risks. Abstract 4760, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025 .
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Publication: Abstracts and Presentations
/ Topics: Exposure Assessment
Schaefer H . An introduction to evidence integration. Abstract 1333, Society of Toxicology 64th Annual Meeting, Orlando, FL, 2025
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Publication: Abstracts and Presentations
/ Topics: evidence-based reviews , NAMs
Jacobellis M , Garcia M, Bain L, Pearce J, Hunt K, Baldwin W. Disruption of energy homeostasis by chemical mixtures containing persistent pollutants in HepG2 and C2C12 cells. Abstract 4564, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Publication: Abstracts and Presentations
/ Topics: chemical safety assessment
Reynolds JI , Yelleti A, Johnson BP. Bridging data gaps in sonic hedgehog signaling: A novel microphysiological model approach. Abstract 3234, Society for Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Publication: Abstracts and Presentations
/ Topics: Adverse outcome pathways (AOPs) , modeling
Covell LT , Han AA, Blanchette AD, Madl AK. Comparison of harmful and potentially harmful constituents (HPHC) and associated excess lifetime cancer risks (ELCR) across oral nicotine products. Abstract 4911, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
Publication: Abstracts and Presentations
/ Topics: Cancer , carcinogens , chemical safety assessment
Blanchette AD, Donnell MT, Covell LT , Madl AK. A machine learning-based framework for predicting carcinogenic potencies for nitrosamine compounds. Abstract 4040, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
Publication: Abstracts and Presentations
/ Topics: carcinogens , computational toxicology
Wood LA, Langton CR, Donnell MT, Covell LT , Blanchette A, Keeton K, Benson SM. Asbestos exposure and para-testicular mesothelioma. Abstract 4586, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
Publication: Abstracts and Presentations
/ Topics: asbestos
Wikoff DS, Vincent MJ, Heintz MM, Pastula ST, Reichert H, Klaren WD, Haws LC . 2025. Application of a quantitative uncertainty assessment to develop ranges of plausible toxicity values when using observational data in risk assessment: A case study examining associations between PFOA and PFOS exposures and vaccine response. Toxicol Sci 204(1):96-115; doi: 10.1093/toxsci/kfae152 . PMID: 39792025.
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Publication: Manuscripts
/ Topics: PFAS , risk assessment , Systematic Review
Nguyen HVM, Cabello E, Dyer D, Fender C , Garcia-Jaramillo M, Hord NG, Austad S, Richardson A, Unnikrishnan A. 2025. Age, sex, and mitochrondrial-haplotype influence gut microbiome composition and metabolites in a genetically diverse rat. Aging 17(2):524-549; doi: 10.18632/aging.206211 . PMID: 40015964.
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Publication: Manuscripts
/ Topics: metabolites
Lea IA , Feifarek D, Mihalchik A, Heintz M, Haws L, Nyambego H, Goyak K, Palermo C, Borghoff SJ . 2025. Evaluation of the endocrine disrupting potential of Di-isodecyl phthalate. Curr Res Toxicol 8:100221; doi: 10.1016/j.crtox.2025.100221 . PMID: 40041033.
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Publication: Manuscripts
/ Topics: phthalates
Kramer A , Vivanco S , Bare J , Panko J . 2025. Analysis of EPA air toxics monitoring data and tools for use in general population exposure assessments: Using acrylonitrile as a case study. J Air Waste Manag Assoc 75(3)181-197; doi: 10.1080/10962247.2024.2438793 . PMID: 39660961.
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Publication: Manuscripts
/ Topics: Air Quality , Exposure Assessment
Pastula ST , Bylsma LC , Rege SV, Lewis RJ, Movva N . 2025. Scoping review of indices to measure a community’s health status. Popul Health Manag 28(1):37-49; doi: 10.1089/pop.2024.0138 . PMID: 39558762.
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Publication: Manuscripts
/ Topics: community health , Epidemiology , scoping review
Pollock D, Marley C, McBride G, Dias M, Kanukula R, Hasanoff S, Price C , et al. 2025. Simulated clinical placements in health care education: A scoping review and evidence and gap map protocol. JBI Evidence Synthesis; https://doi.org/10.11124/JBIES-24-00298 .
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Publication: Protocol Registrations
/ Topics: scoping review
Verwiel A, Rish W . 2025. Multidisciplinary perspectives on cumulative impact assessment for vulnerable communities: Expert elicitation using a Delphi method. Integr Environ Assess Manag 21(2):301-313; doi: 10.1093/inteam/vjae051 . PMID: 39881570.
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Publication: Manuscripts
/ Topics: Air Quality , risk assessment
Seal S, Trapotsi MA, Spjuth O, Singh S, Carreras-Puigvert J, Greene N , Bender A, Carpenter AE. 2025. Cell painting: A decade of discovery and innovation in cellular imaging. Nat Meth 22(2):254-268 ; doi: 10.1038/s41592-024-02528-8 . PMID: 39639168.
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Publication: Manuscripts
/ Topics: computational toxicology
Wikoff D . Use cases of strategic application of ML/AI in the risk assessment process. Toxicology Forum 2025 Winter Meeting, Raleigh, NC, February 2025.
Publication: Abstracts and Presentations
/ Topics: Food science , risk assessment
Wikoff D . Pragmatic solutions for better using evidence-based methods to integrate observational data in food safety assessments. Toxicology Forum 2025 Winter Meeting, Raleigh, NC, February 2025.