2016 (135 POSTS)
Borghoff SJ , Wikoff D , Harvey S , Haws L . 2016. Dose- and time-dependent changes in tissue levels of tetrabromobisphenol A (TBBPA) and its sulfate and glucuronide conjugates following repeated administration to female Wistar Han Rats. Toxicol Rep 3:190-201. doi: 10.1016/j.toxrep.2016.01.007 .
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Publication: Manuscripts
/ Topics: flame retardants
Doepker C , Lieberman HR, Smith AP, Peck JD, El-Sohemy A, Welsh BT. 2016. Caffeine: Friend or foe? Annu Rev Food Sci Technol 7(Feb):117-137; doi: 10.1146/annurev-food-041715-033243 .
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Publication: Manuscripts
/ Topics: Food science , pharmacology
Sisler JD, Li R, McKinney W, Mercer RR, Ji Z, Xia T, Wang X, Shaffer J, Orandle M, Mihalchik AL , Battelli L. 2016. Differential pulmonary effects of CoO and La2 O3 metal oxide nanoparticle responses during aerosolized inhalation in mice. Particle Fibre Toxicol 13(1):42; doi: 10.1186/s12989-016-0155-3 .
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Publication: Manuscripts
/ Topics: nanomaterials
Sisler JD, Pirela SV, Shaffer J, Mihalchik AL , Chisholm WP, Andrew ME, Schwegler-Berry D, Castranova V, et al. 2016. Toxicological assessment of CoO and La2 O3 metal oxide nanoparticles in human small airway epithelial cells. Toxicol Sci 150(2):418-428; doi: 10.1093/toxsci/kfw005 .
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Publication: Manuscripts
/ Topics: nanomaterials
2015 (107 POSTS)
Proctor DM , Suh M , Mittal L , Hirsch S, Salgado RV, Bartlett C, Van Landingham C, Rohr A, Crump K. 2015. Inhalation cancer risk assessment of hexavalent chromium based on updated mortality for Painesville chromate production workers. J Expo Sci Environ Epidemiol 26(2):224-231. doi: 10.1038/jes.2015.77 .
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Publication: Manuscripts
/ Topics: Cancer , chromium , risk assessment
Sahmel J, Avens HJ, Scott PK, Unice K, Burns A , Barlow CA, Madl AK, Henshaw J, Paustenbach DJ. 2015. Measured removal rates of chrysotile asbestos fibers from air and comparison with theoretical estimates based on gravitational settling and dilution ventilation. Inhal Toxicol 27(14):787-801; doi: 10.3109/08958378.2015.1110216 . PMID: 26671197.
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Publication: Manuscripts
/ Topics: asbestos
Wirbisky SE , Freeman JL. 2015. Atrazine exposure and reproductive dysfunction through the hypothalamus-pituitary-gonadal (HPG) axis. Toxics 3:414–450; doi: 10.3390/toxics3040414 .
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Publication: Manuscripts
/ Topics: atrazine
Madl AK, Kovochich M, Liong M, Finley BL , Paustenbach DJ, Oberdorster G. 2015. Toxicology of wear particles of cobalt-chromium alloy metal-on-metal hip implants Part II: Importance of physiochemical properties and dose in animal and in vitro studies as a basis for risk assessment. Nanomed: Nanotech Biol Med 11(5):1285–1298; doi: 10.1016/j.nano.2015.02.006 . PMID: 25735266.
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Publication: Manuscripts
/ Topics: chromium , cobalt , Metals , risk assessment
James RC, Britt JK , Halmes NC, Guzelian PS. 2015. Evidence-based causation in toxicology: A 10-year retrospective. Hum Exp Toxicol 34(12):1245–1252; doi: 10.1177/0960327115601767 .
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Publication: Manuscripts
/ Topics: Toxicology
Wheeler MW, Park R, Bailer A, Whittaker C. 2015. Historical context and recent advances in exposure-response estimation for deriving occupational exposure limits. J Occup Environ Hyg 12(sup1):S7-S17; doi: 10.1080/15459624.2015.1076934 . PMCID: PMC4685605.
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Publication: Manuscripts
/ Topics: benchmark dose estimation (BMD) , dose-response , modeling , Occupational , Occupational exposure limits (OELs)
Strickland J, Zang Q, Paris M, Kleinstreuer N, Lehmann DM, Allen D, Choksi N , et al. Machine learning approaches for predicting human skin sensitization hazard. Poster presented at FutureToxIII, Baltimore, MD, November 2015
Publication: Abstracts and Presentations
/ Topics: Exposure Assessment
Becker RA, Patlewicz G , Simon T, Rowlands JC, Budinsky RA. 2015. The adverse outcome pathway for rodent liver tumor promotion by sustained activation of the aryl hydrocarbon receptor. Regul Toxicol Pharmacol 73(1):172-190; doi: 10.1016/j.yrtph.2015.06.015 . PMID: 26145830.
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Publication: Manuscripts
/ Topics: Adverse outcome pathways (AOPs) , mode of action
Wikoff D , Doepker C , Welsh B, Urban J , Henderson R , Britt J , Harvey S , Goldberger J, Myers E, O’Brien C, Peck J, Lieberman H, Weaver C, Tenebein M. 2015. Systematic review of the adverse bone and calcium balance effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children. PROSPERO 2015:CRD42015026609 Available from http://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42015026609 (Systematic Review Protocol Registration)
Publication: Protocol Registrations
/ Topics: Systematic Review
Wikoff D , Doepker C , Welsh B, Urban J , Henderson R , Brorby G , Britt J , Harvey S , Goldberger J, Myers E, O’Brien C, Peck J, Lieberman H, Weaver C, Tenebein M. 2015. Systematic review of the adverse cardiovascular effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children. PROSPERO 2015:CRD42015026673 Available from http://www.crd.york.ac.uk/PROSPERO/display_record. asp?ID=CRD42015026673 (Systematic Review Protocol Registration)
Publication: Protocol Registrations
/ Topics: Systematic Review
Ulrich K . Inhalation toxicology – Regulatory aspects for pharmaceuticals. Presentation to In Vitro Toxicology Society Annual Meeting, Birmingham, UK, 2015.
Publication: Abstracts and Presentations
/ Topics: pharmacology , regulatory toxicology
Ulrich, K. Requirements of nonclinical inhalation studies for clinical development and registration. Presentation to British Society of Toxicological Pathologists (BSTP) — Continuing Education Symposium 4, Department of Pathology, Cambridge, UK, 2015.
Publication: Abstracts and Presentations
/ Topics: Toxicology
Katz AJ, Chia VM, Schoonen WM, Kelsh MA . 2015. Acute lymphoblastic leukemia: An assessment of international incidence, survival, and disease burden. Cancer Causes Control 26(11):1627–1642.
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Publication: Manuscripts
/ Topics: Cancer , Epidemiology
Mackay CE, Vivanco SN , Reinhardt TE, McClure S, Vercellone J. 2015. Real-time monitoring and assessment of thermal and toxicological risk associated with fire retardant textiles in a full-size simulation of an engulfment flash fire. Fire Technol 51(5):1167–1193; doi: 10.1007/s10694-015-0456-3 .
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Publication: Manuscripts
/ Topics: flame retardants , risk assessment
Kelsh MA , Chia VM. Historical comparator studies: Strengths, limitations, and analytical considerations in using historical pooled clinical data for evaluating efficacy and safety of new therapies. Presented at International Conference on Pharmacoepidemiology and Therapeutic Risk Management (ICPE) Boston, MA, August 25, 2015.
Publication: Abstracts and Presentations
/ Topics: Epidemiology
Hughes BJ, LeBaron MJ, Thomas J, Kan HL, Lynch AM, Borghoff SJ , Green S, Mensing T, Sarang SS, Smulders CJGM. 2015. Activation of CAR and PXR nuclear receptors in the liver of MIBK-exposed mice. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.
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