Publication Topic

Sheridan ER, Jackson M, Paleja A, Martini C, Rashid A, Lea I, Fostel J. Improved searching in the Chemical Effects in Biological Systems (CEBS) database leads to greater utility of NTP data. Abstract 2525-P887, Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.

Williams A, Grulke C, Edwards J, McEachran A, Mansouri K, Baker N, Patlewicz G, Shah I, et al. 2017. The CompTox Chemistry Dashboard–A community data resource for environmental chemistry. J Cheminform 9(1):61; doi: 10.1186/s13321-017-0247-6. PMID: 29185060.

Liu J, Patlewicz G, Williams A, Thomas RS, Shah I. 2017. Predicting organ toxicity using in vitro bioactivity data and chemical structure. Chem Res Toxicol 30(11):2046-2059; doi: 10.1021/acs.chemrestox.7b00084. PMID: 28768096.

Sheridan E, Martini C, Shaw M, Shockley K, Brix A, Rashid A, Lea I, Fostel J. Using the Chemical Effects in Biological Systems (CEBS) database to answer pathology questions. Poster P035. Presented at the 36th Annual Symposium of Society for Toxicologic Pathology, Montreal, Quebec, Canada, June 2017.

Lea IA, Gong H, Paleja A, Rashid, A, Foster J. 2017. CEBS: A comprehensive annotated database of toxicological data. Nucleic Acids Res 45(D1):D964–D971; doi: 10.1093/nar/gkw1077. PMID: 27899660.

Roberts DW, Api AM, Patlewicz G, Schultz TW. 2016. Chemical applicability domain of the Local Lymph Node Assay (LLNA) for skin sensitization potency. Part 1. Underlying physical organic chemistry principles and the extent to which they are represented in the LLNA validation dataset. Regul Toxicol Pharmacol 80(Oct):247-254; doi: 10.1016/j.yrtph.2016.07.007. PMID: 27424000.

Patlewicz G, Worth AP, Ball N. 2016. Validation of computational methods. Adv Exp Med Biol 856:165-187; doi: 10.1007/978-3-319-33826-2_6. PMID: 27671722.

Strickland J, Zang Q, Kleinstreuer N, Paris M, Lehmann DM, Choksi N, et al. 2016. Integrated decision strategies for skin sensitization hazard. J Appl Toxicol 36(9):1150–1162; doi: 10.1002/jat.3281. PMID: 26851134.

Richard A, Judson R, Houck K, Grulke C, Volarath P, Thillainadarajah I, Yang C,…, Patlewicz G, et al. 2016. The ToxCast chemical landscape: Paving the road to 21st century toxicology. Chem Res Toxicol 29(8):1225-1251; doi: 10.1021/acs.chemrestox.6b00135. PMID: 27367298.

Patlewicz GY, Fitzpatrick J. 2016. Current and future perspectives on the development, evaluation and application of in silico approaches for predicting toxicity. Chem Res Toxicol 29(4):438-451; doi: 10.1021/acs.chemrestox.5b00388. PMID: 26686752.

Ball N, Cronin MTD, Shen J, Blackburn K, Booth ED, Bouhifd M, Donley E,…, Patlewicz G, et al. 2016. Toward good read-across practice (GRAP) guidance. ALTEX 33(2):149-166; doi: 10.14573/altex.1601251. PMID: 26863606.

Greene N, Pennie W. 2015. Computational toxicology: Friend or foe? Toxicol Res 4(5):1159-1172; doi: 10.1039/c5tx00055f.

Steinbach T, Gad-McDonald S, Kruhlak N, Powley M, Greene N. 2015. (Q)SAR: A tool for the toxicologist. Int J Toxicol 34(4):352-4; doi: 10.1177/1091581815584914. PMID: 25979517.

Greene N, Dobo KL, Kenyon MO, Cheung J, Munzner J, Sobol Z, Sluggett G, Zelesky T, et al. 2015. A practical application of two in silico systems for identification of potentially mutagenic impurities. Regul Toxicol Pharmacol 72(2):335-49; doi: 10.1016/j.yrtph.2015.05.008. PMID: 25980641.

Panko JM. Chemical selection tools analysis project and results. Presented at GlobalChem. Global Chemical Regulations Conference, Baltimore, MD, March 2014.

Sutter A, Amberg A, Boyer S, Brigo A, Contrera JF, Custer LL, Dobo KL,…, Greene N, et al. 2013. Use of in silico systems and expert knowledge for structure-based assessment of potentially mutagenic impurities. Regul Toxicol Pharmacol 67(1):39-52; doi: 10.1016/j.yrtph.2013.05.001. PMID: 23669331.

Greene N, Gosink M. 2013. Computational toxicology experience and applications for risk assessment in the pharmaceutical industry. Chapter 10 in: Fowler BA (ed), Computational Toxicology: Methods and Applications. Elsevier-Academic Press, pp. 171-193; doi: 10.1016/B978-0-12-396461-8.00012-9.

Shah F, Greene N. 2013. Analysis of Pfizer compounds in EPA’s ToxCast chemicals-assay space. Chem Res Toxicol 27(1):86-98; doi: 10.1021/tx400343t. PMID: 24328225.

Naven RT, Greene N, Williams RV. 2012. Latest advances in computational genotoxicity prediction. Exp Opin Drug Metabol 8(12):1579-87; doi: 10.1517/17425255.2012.724059. PMID: 22998164.

Dobo KL, Greene N, Fred C, Glowienke S, Harvey JS, Hasselgren C, Jolly R, Kenyon MO, et al. 2012. In silico methods combined with expert knowledge rule out mutagenic potential of pharmaceutical impurities: An industry survey. Regul Toxicol Pharmacol 62(3):449-455; doi: 10.1016/j.yrtph.2012.01.007. PMID: 22321701.