2017 (60 POSTS)
Franzen A , Greene T, Van Landingham C, Gentry R. 2017. Toxicology of octamethylcyclotetrasiloxane (D4). Toxicol Lett 279(Suppl 1):2–22. doi: 10.1016/j.toxlet.2017.06.007 . PMID: 28645863.
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Topics: inhalation toxicology , mode of action , pharmacokinetics
Huddle MG, Goman AM, Kernizan FC, Foley DM, Price C , Frick KD, Lin FR. 2017. The economic impact of adult hearing loss: A systematic review. JAMA Otolaryngol: Head Neck Surg 143(10):1040–1048; doi: 10.1001/jamaoto.2017.1243 .
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Topics: hearing loss , Systematic Review
Shao K, Allen BC, Wheeler MW . 2017. Bayesian hierarchical structure for quantifying population variability to inform probabilistic health risk assessments. Risk Anal 37(10):1865-78; doi: 10.1111/risa.12751 .PMCID: PMC6151353.
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Topics: Bayesian modeling , risk assessment
Rager JE, Auerbach SS, Chappell GA, Martin E, Thompson C , Fry RC. 2017. Benchmark dose modeling estimates of the concentrations of inorganic arsenic that induce changes to the neonatal transcriptome, proteome, and epigenome in a pregnancy cohort. Chem Res Toxicol 30(10):1911-1920; doi: 10.1021/acs.chemrestox.7b00221 .
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Topics: arsenic , benchmark dose estimation (BMD)
Thompson CM, Suh M, Proctor DM, Haws LC , Harris MA. 2017. Ten factors for considering the mode of action of Cr(VI)-induced gastrointestinal tumors in rodents. Mutat Res 823(Nov):45-57; doi: 10.1016/j.mrgentox.2017.08.004 .
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Topics: chromium , mode of action
Patlewicz G , Helman G, Pradeep P, Shah I. 2017. Navigating through the minefield of read-across tools: A review of in silico tools for grouping. Comput Toxicol 3(Aug):1-18; doi: 10.1016/j.comtox.2017.05.003 . PMID: 30221211.
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Topics: read-across
Butler LD, Guzzie-Peck P, Hartke J, Bogdanffy MS, Will Y, Diaz D, Mortimer-Cassen E,…, Greene N , et al. 2017. Current nonclinical testing paradigms in support of safe clinical trials: An IQ Consortium DruSafe perspective. Regul Toxicol Pharmacol 87(Sup 3):S1-S15; doi: 10.1016/j.yrtph.2017.05.009 . PMID: 28483710.
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Topics: drug development , nonclinical safety assessment
Thompson CM , Young RR, Dinesdurage H, Suh M , Harris MA, Rohr AC, Proctor DM . 2017. Assessment of the mutagenic potential of hexavalent chromium in the duodenum of Big Blue® rats. Toxicol Appl Pharmacol 330(1):48-52; 10.1016/j.taap.2017.07.002 .
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Topics: chromium
Schaefer HR , Myers, JL. 2017. Development of an inhalation unit risk factor for ethylene dibromide. Inhal Toxicol 29(7):304-309; doi: 10.1080/08958378.2017.1369603 . PMID: 28891353.
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Topics: inhalation toxicology
Iwata Y, Klaren WD , Lebakken CS, Grimm FA, Rusyn I. 2017. High-content assay multiplexing for vascular toxicity screening in induced pluripotent stem cell-derived endothelial cells and human umbilical vein endothelial cells. Assay Drug Dev Technol 15(6):267–279; doi; 10.1089/adt.2017.786 . PMID: 28771372.
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Topics: Toxicology
Klaren WD , Vine D, Vogt S, Robertson LW. 2017. Spatial distribution of metals within the liver acinus and their perturbation by PCB126. Environ Sci Pollut Res Int 25(17):16427–16433; doi: 10.1007/s11356-017-0202-0 .
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Topics: Metals
Panko J , Hitchcock K, Fung M, Spencer PJ, Kingsbury T, Mason AM. 2017. A comparative evaluation of five hazard screening tools. Integr Environ Assess Manag 13(1):139–154.
See also: Panko J , Hitchcock K, Fung M, Spencer PJ, Kingsbury T, Mason AM. 2017. Letter to the Editor: Authors’ response to Turner et al. Integr Environ Assess Manag 13(1):15–16.
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Topics: Toxicology
Perez AL, Gauthier AM, Ferracini T, Cowan DM, Kingsbury T, Panko J . 2017. The challenge of predicting problematic chemicals using a decision analysis tool: Triclosan as a case study. Integr Environ Assess Manag 13(1):198–207; doi: 10.1002/ieam.1778 .
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Topics: Toxicology
Burns A , Shin J, Unice KM, Gaffney SH, Kreider ML, Gelatt RN, Panko JM . 2017. Combined analysis of job and task benzene air exposures among workers at four US refinery operations. Toxicol Ind Health 33(3):193–210; doi: 10.1177/0748233715619072 . PMID: 26862134.
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Topics: benzene , Occupational , Refineries
Judson RS, Martin M, Patlewicz G , Wood CE. 2017. Retrospective mining of toxicology data to discover multispecies and chemical class effects: Anemia as a case study. Regul Toxicol Pharmacol 86(June):74-92; doi: 10.1016/j.yrtph.2017.02.015 . PMID: 28242142.
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Topics: modeling
Wang Y, Villalta PW, Peng L, Dingley KH , Malfatti MA, Turteltaub KW, Turesky RJ. 2017. Mass spectrometric characterization of an acid-labile adduct formed with 2-amino-1-methyl-phenylimidazo[4,5-b]pyridine and albumin in humans. Chem Res Toxicol 30(2):705–714; doi: 10.1021/acs.chemrestox.6b00426 . PMID: 27984695.
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Topics: carcinogens
Harper BH, Wang L, Zhu C, Kar NF, Li B, Moyes CR, … Dingley K , et al. 2017. Investigation of piperazine benzamides as human β3 adrenergic receptor agonists for the treatment of overactive bladder. Bioorg Med Chem Lett 27(4):1094–1098; doi: 10.1016/j.bmcl.2016.12.033 . PMID: 28089699.
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