2007 (32 POSTS)
Covington TR , Gentry PR, Van Landingham CB, Andersen ME, Kester JE, Clewell HJ. 2007. The use of Markov chain MonteCarlo uncertainty analysis to support a Public Health Goal for perchloroethylene. Regul Toxicol Pharmacol 47(1):1– 18; doi: 10.1080/20024091064264 . PMID: 16901594.
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Topics: PBPK/PBDE , risk analysis
Woods CG, Burns AM , Maki A, Bradford BU, Cunningham ML, Connor HD, Kadiiska MB, Mason RP, et al. 2007. Sustained formation of alpha-(4-pyridyl-1-oxide)-N-tert-butylnitrone radical adducts in mouse liver by peroxisome proliferators is dependent upon peroxisome proliferator-activated receptor-alpha, but not NADPH oxidase. Free Radic Biol Med 42(3):335-342; doi: 10.1016/j.freeradbiomed.2006.10.053 . PMID: 17210446.
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Topics: oxidative stress
Paustenbach DJ, Panko JM , Scott PK, Unice KM. 2007. A methodology for estimating human exposure to perfluorooctanoic acid (PFOA): A retrospective exposure assessment of a community (1951-2003). J Toxicol Environ Health A 70(1):28–57; doi: 10.1080/15287390600748815 . PMID: 17162497.
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Topics: community health , Exposure Assessment , PFAS
Urban JD , Vargas G, von Zastrow M, Mailman RB. 2007. Aripiprazole has functionally selective actions at D2 receptor-mediated signaling pathways. Neuropsychopharmacol 32(1):67-77; doi: 10.1038/sj.npp.1301071 . PMID: 16554739.
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Topics: drug interactions
2006 (27 POSTS)
Rogers JM . 2006. Casting a broad network: Fishing for mechanisms of retinoid teratogenicity. Toxicological highlight. Toxicol Sci 94(1):1–2; doi: 10.1093/toxsci/kfl104 . PMID: 17167877.
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Topics: transcriptomics
Staskal DF , Hakk H, Bauer D, Diliberto JJ, Birnbam LS. 2006. Toxicokinetics of polybrominated diphenyl ether congeners 47, 99, 100, and 153 in mice. Toxicol Sci 94(1):28-37; doi: 10.1093/toxsci/kfl091 . PMID: 16936226.
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Topics: flame retardants , PBPK/PBDE , toxicokinetics
Cher DJ, Deubner DC, Kelsh MA , Chapman PS, Ray RM. 2006. Assessment of the beryllium lymphocyte proliferation test using statistical process control. Inhal Toxicol 18(11):901–910; doi: 10.1080/08958370600822631 . PMID: 16864408.
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Topics: beryllium , Epidemiology , Metals
Alexander DD, Mink PJ, Mandel JH, Kelsh MA . 2006. A meta-analysis of occupational trichloroethylene exposure and multiple myeloma or leukemia. Occup Med 56(7):485–493; doi: 10.1093/occmed/kql083 . PMID: 16905622.
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Topics: Cancer , meta-analysis , Occupational , trichloroethylene
Becker DS, Long ER, Proctor DM , Ginn TC. 2006. Toxicity and bioavailability of chromium in sediments associated with chromite ore processing residue. Environ Toxicol Chem 25(10):2576–2583; doi: 10.1897/05-494R.1 . PMID: 17022396.
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Topics: chromium
Van den Berg M, Birnbaum L, Denison M, De Vito M, Farland W, Feeley M, Fiedler H,…, Haws LC , et al. 2006. The 2005 World Health Organization reevaluation of human and mammalian toxic equivalency factors for dioxins and dioxin-like compounds. Toxicol Sci 93(2):223-241; doi: 10.1093/toxsci/kfl055 . PMID: 16829543.
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Topics: dioxin
Mandel JH, Kelsh MA , Mink PJ, Alexander D, Kalmes RM, Weingart M, et al. 2006. Occupational trichloroethylene exposure and non-Hodgkins lymphoma: A meta-analysis and review. Occup Environ Med 63(9):597–607; doi: 10.1136/oem.2005.022418 . PMID: 16644896.
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Topics: Cancer , meta-analysis , Occupational , trichloroethylene
Barone S Jr., Brown RC, Euling S, Cohen Hubal E, Kimmel CA, Makris S, Moya J,…, Thompson CM . 2006. Visión general de la evaluación del rieso en salud infantil empleando un enfoque por etapas de desarrollo. Acta Toxicol Argent 14(Suppl):7–10 .
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Topics: Epidemiology
Rose WC, Marathe PH, Jang G, Monticello TM , Balasubramanian BN, Long B, Fairchild C, Wall ME, Wani MC. 2006. Novel fluoro-substituted campthothecins: In vivo antitumor activity, reduced gastrointestinal toxicity and pharmacokinetic characterization. Cancer Chemother Pharmacol 58(1):73-85; doi: 10.1007/s00280-005-0128-y . PMID: 16228206.
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Topics: drug development , pharmacokinetics
David RM, Clewell HJ, Gentry PR, Covington TR , Morgott DA, Marino DJ. 2006. Revised assessment of cancer risk to dichloromethane II. Application of probabilistic methods to cancer risk determinations. Regul Toxicol Pharmacol 45(1):55–65; doi: 10.1016/j.yrtph.2005.12.003 . PMID: 16439044.
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Topics: Cancer , PBPK/PBDE
Marino DJ, Clewell HJ, Gentry PR, Covington TR , Hack CE, David RM, Morgott DA. 2006. Revised assessment of cancer risk to dichloromethane: Part I Bayesian PBPK and dose-response modeling in mice. Regul Toxicol Pharmacol 45(1):44–54; doi: 10.1016/j.yrtph.2005.12.007 . PMID: 16442684.
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Topics: Bayesian modeling , Cancer , dose-response , modeling , PBPK/PBDE , risk assessment
Degregorio MW, Dingley KH , Wurz GT, Ubick E, Turteltaub KW. 2006. Accelerator mass spectrometry allows for cellular quantification of doxorubicin at femtomolar concentrations. Cancer Chemother Pharmacol 57(3):335-342; doi: 10.1007/s00280-005-0060-1 . PMID: 16047147.
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Topics: Cancer , spectrometry
Tompkins EM, Farmer PB, Lamb JH, Jukes R, Dingley K , Ubick E, et al. 2006. A novel 14C-postlabeling assay using accelerator mass spectrometry for the detection of O6-methyldeoxy-guanosine adducts. Rapid Commun Mass Spectrom 20(5):883–891; doi: 10.1002/rcm.2370 . PMID: 16470516.
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Topics: spectrometry
Borowsky AD, Dingley KH , Ubick E, Turteltaub KW, Cardiff RD, Devere-White R. 2006. Inflammation and atrophy precede prostatic neoplasia in a PhIP-induced rat model. Neoplasia 8(9):708–715; doi: 10.1593/neo.06373 . PMID: 16984728.
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Topics: carcinogens
Malfatti MA, Dingley KH , Nowell-Kadlubar S, Ubick EA, Mulakken N, Nelson D, Lang NP, et al. 2006. The urinary metabolite profile of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine is predictive of colon DNA adducts after a low-dose exposure in humans. Cancer Res 66(21):10541–10547; doi: 10.1158/0008-5472.CAN-06-1573 . PMID: 17079477.
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Topics: Cancer , carcinogens
Wheeler MW , Park RM, Bailer AJ. 2006. Comparing median lethal concentration values using confidence interval overlap or ratio tests. Environ Toxicol Chem 25(5):1441-4; doi: 10.1897/05-320r.1. PMID: 16704080.
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