2006 (27 POSTS)
Leighton JK, Brown P, Ellis A, Harlow P, Harrouk W, Pine PS, Robison T , Rosario L, Thompson K. 2006. Workgroup Report: Review of genomic data based on experience with mock submissions: View of the CDER Pharmacology Toxicology Nonclinical Pharmacogenomics Subcommittee. Environ Health Perspect 114:573-578; doi: 10.1289/ehp.8318 .
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Staskal DF , Diliberto JJ, Birnbam LS. 2006. Disposition of BDE 47 in developing mice. Toxicol Sci 90(2):309-16; doi: 10.1093/toxsci/kfj098 . PMID: 16407092.
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Topics: flame retardants , PBPK/PBDE
Jackson MA, Lea I , Rashid A, Peddada SD, Dunnick JK. 2006. Genetic alterations in cancer knowledge system: Analysis of gene mutations in mouse and human liver and lung tumors. Toxicol Sci 90(2):400–418; doi: 10.1093/toxsci/kfj101 . PMID: 16410370.
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Topics: Cancer
Mezei G, Cher D, Kelsh M , Edinboro C, Chapman P, Kavet R. 2005. Occupational magnetic field exposure, cardiovascular disease mortality, and potential confounding by smoking. Ann Epidemiol 15(8):622–629; doi: 10.1016/j.annepidem.2004.12.013 .
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Topics: Electric and Magnetic Fields (EMF)
Niple JC, Sahl JD, Kelsh MA , Kavet R. 2005. Equipment grounding affects contact current exposure: A case study of sewing machines. Ann Occup Hyg 49(8):673–682; doi: 10.1093/annhyg/mei031 .
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Topics: Electric and Magnetic Fields (EMF)
Staskal DF , Diliberto JJ, Birnbaum LS. 2006. Impact of repeated exposure on the toxicokinetics of BDE 47 in mice. Toxicol Sci 89(2):380-5; doi: 10.1093/toxsci/kfj038 . PMID: 16280385.
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Topics: Exposure Assessment , flame retardants , toxicokinetics
Rose WC, Marathe PH, Jang G, Monticello TM , Balasubramanian BN, Long B, Fairchild C, Wall ME, Wani MC. 2006. Novel fluoro-substituted campthothecins: In vivo antitumor activity, reduced gastrointestinal toxicity and pharmacokinetic characterization. Cancer Chemother Pharmacol 58(1):73-85; doi: 10.1007/s00280-005-0128-y .
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Topics: drug development , pharmacokinetics
2005 (19 POSTS)
Celli BR, Halbert RJ, Nordyke RJ , Schau B. 2005. Airway obstruction in never smokers: Results from the third National Health and Nutrition Examination Survey. Am J Med 118(12):1364-72; doi: 10.1016/j.amjmed.2005.06.041 . PMID: 16378780.
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Topics: Epidemiology , NHANES
Grasty RC , Bjork JA, Wallace KB, Lau CS, Rogers JM . 2005. Effects of prenatal perfluorooctane sulfonate (PFOS) exposure on lung maturation in the perinatal rat. Birth Defects Res B 74(5):405–416; doi: 10.1002/bdrb.20059 . PMID: 6249997.
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Topics: PFAS
Ulrich K , Stern M, Goddard ME, Williams J, Zhu J, Dewar A, Painter HA, Jeffery PK, et al. 2005. Keratinocyte growth factor therapy in murine oleic acid-induced acute lung injury. Lung Cell Molec Physiol 288(6):L1179-92; doi: 10.1152/ajplung.00450.2004 . PMID: 15681392.
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Topics: drug development
Ebeler SE, Dingley KH , Ubick E, Abel S, Mitchell AE, Burns SA, et al. 2005. Animal models and analytical approaches for understanding the relationships between wine and cancer. Drugs Exp Clin Res 31(1):19–27. PMID: 15921026 .
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Topics: Cancer , Food science
Rickert DE, Dingley K , Ubick E, Dix KJ, Molina L. 2005. Determination of the tissue distribution and excretion by accelerator mass spectrometry of the nonadecapeptide 14C-Moli1901 in beagle dogs after intratracheal instillation. Chem Biol Interact 155(1–2):55–61; doi: 10.1016/j.cbi.2005.04.002 . PMID: 15893299.
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Topics: spectrometry
Bailer AJ, Wheeler MW , Dankovic D, Noble R, Bena J. 2005. Incorporating uncertainty and variability in the assessment of occupational hazards. Int J Risk Assess Manage 5(2-4):344-57; doi: 10.1504/IJRAM.2005.007176 .
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Topics: Exposure Assessment , modeling , Occupational , risk analysis , risk assessment
van Schayck CP, Halbert RJ, Nordyke RJ , Isonaka S, Maroni J, Nonikov D. 2005. Comparison of existing symptom-based questionnaires for identifying COPD in the general practice setting. Respirology 10(3):323-33; doi: 10.1111/j.1440-1843.2005.00720.x . PMID: 15955145.
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Topics: Epidemiology
Fukuhara S, Nishimura M, Nordyke RJ , Zaher CA, Peabody JW. 2005. Patterns of care for COPD by Japanese physicians. Respirology 10(3):341-8; doi: 10.1111/j.1440-1843.2005.00717.x . PMID: 15955147.
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Topics: Epidemiology
Brown K, Dingley KH , Turteltaub KW. 2005. Accelerator mass spectrometry for biomedical research. Methods Enzymol 402:423–443; doi: 10.1016/S0076-6879(05)02014-8 . PMID: 16401518.
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Topics: spectrometry
Teeguarden JG, Waechter JM Jr, Clewell HJ 3rd, Covington TR , Barton HA. 2005. Evaluation of oral and intravenous route pharmacokinetics, plasma protein binding and uterine tissue dose metrics of bisphenol A: A physiologically based pharmacokinetic approach. Toxicol Sci 85(2):429–446; doi: 10.1093/toxsci/kfi135 .
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Topics: PBPK/PBDE , pharmacokinetics
Gentry PR, Haber LT, McDonald TB, Zhao Q, Covington T , Nance P, Clewell HJ III, Lipscomb JC, Barton HA. 2005. Data for physiologically based pharmacokinetic modeling in neonatal animals: Physiological parameters in mice and Sprague-Dawley rats. J Children’s Health 2(3–4):363–411; doi: 10.3109/15417060490970430 .
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