Publications

Covington T, Robinson P, Gearhart J. Exploring issues in simulating dermal exposure using a physiologically-based pharmacokinetic-pharmacodynamic (PBPK-PD) model for VX. Poster presented at the Society of Toxicology Annual Meeting, Washington, DC, March 2011.

Fitzgerald L, Burkhalter B, Urban J, Staskal D, Harris M, Haws L. VOC serum levels in the general U.S. population: An analysis of the 2003-2004 NHANES dataset. Presented at Society of Toxicology 50th Annual Meeting, Washington, D.C., March 2011

Sistare FD, Morton D, Alden C, Christensen J, Keller D, Jonghe SD, et al. 2011. An analysis of pharmaceutical experience with decades of rat carcinogenicity testing: Support for a proposal to modify current regulatory guidelines. Toxicol Pathol 39(4):716–744; doi: 10.1177/0192623311406935.

Hinerman J, Herr A. Determining the mechanism of activation of glycoprotein VI. Poster presented to the Ohio Valley Crystallographic Symposium Meeting, Cleveland, OH, November 2011.

Hart BR, Mishra PK, Lintner RE, Hinerman JM, Herr AB, Blumenthal RM. 2011. Recognition of DNA by the helix-turn-helix global regulatory protein Lrp is modulated by the amino terminus. J Bacteriol 193(15):3794–3803.

Haws L, Proctor D, Thompson C, Harris M. 2011. Research plan to fill data gaps in the mode of action for cancer risk assessment of hexavalent chromium in drinking water. Presented at the Society of Toxicology’s 50th Annual Meeting, March 6-10, Washington, D.C.

Tichomirowa MA, Bariler A, Daly AF, Jaffrain-Rea M-L, Ronchi CL, Yaneva M, Urban JD, Petrossians P, et al. 2011. High prevalence of AIP gene mutations following focused screening in young patients with sporadic pituitary macroadenomas. Eur J Endocrinol 165(4):509-515; doi: 10.1530/EJE-11-0304.

Henderson RG, Cappellini D, Seilkop S, Oller A, Bates H. Bioaccessibility-based read-across assessment of nickel compounds for oral systemic toxicity. Presented at Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.

Urban JD, Rowlands JC, Budinsky RA. 2011. Single nucleotide polymorphisms in the human aryl hydrocarbon receptor nuclear translocator (ARNT) gene. Drug Metab Pharmacokinet 26(6):637-645; doi: 10.2133/dmpk.DMPK-11-SC-031.

Kim S, Thompson CM, Kopec AK, Harris MA, Zacharewski TR. Comparison of basal and CrVI-mediated solute carrier gene expression in rodent duodenal epithelium. Presented at Society of Toxicology 50th Annual Meeting, Washington, D.C., March 2011.

Wilson VS, Keshava N, Hester S, Segal D, Chiu W, Thompson CM, Euling SY. 2013. Utilizing toxicogenomic data to understand chemical mechanism of action in risk assessment. Toxicol Appl Pharmacol 271(3):299–308; doi: 10.1016/j.taap.2011.01.017.

Proctor D, Haws L, Thompson C, Harris M. 2011. Use of mode of action and pharmacokinetics to inform the cancer risk assessment of ingested Cr(VI): A case study. Presented at the Society of Toxicology 50th Annual Meeting, March 6-10, 2011, Washington, D.C.

Proctor D, Meek B. Using mode of action data to guide quantitative cancer risk assessment: A case study of hexavalent chromium in drinking water. Presented at Society of Toxicology 50th Annual Meeting, March 6-10, Washington, DC, March 2011.

Staskal-Wikoff D, Budinsky R, Rowlands JC. Single nucleotide polymorphisms in the human aryl hydrocarbon receptor interacting protein (AIP) gene from six ethnic populations. Presented at Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.

Franke K, Paustenbach D. 2011. Government and Navy knowledge regarding health hazards of asbestos: A state of the science evaluation (1900 to 1970). Inhal Toxicol 23(S3):1–20; doi: 10.3109/08958378.2011.643417.

Yong M, Kuehn C, Kelsh M, Mitchell M, et al. Associations between platelet count and survival and disease progression in thrombocytopenic patients with myelodysplastic syndromes. Presented at the American Society of Hematology, Orlando, FL, December 2010

Johns DO, Owens EO, Thompson CM, Sonawane B, Hattis D, Krishnan K. 2010. Physiological parameters and databases for PBPK modeling. Chapter 5 in: Quantitative Modeling in Toxicology. Krishnan K, Andersen M (eds.). Wiley, p. 107.

Harris M, Tachovsky JA, Staskal-Wikoff D, Aylward L, Burkhalter B, Simon T, Haws L. Serum concentrations of dioxin-like compounds in a population in Midland, Michigan: An evaluation of the impact of soil exposures. Presented at Dioxin 2010, San Antonio, TX, September 2010.

Sterner TR, Ruark CD, Covington TR, Hack CE, Gearhart JM. Characterizing uncertainty and population variability in a PBPK-PD mathematical model for the oxime HI-6. Poster presented at the Chemical and Biological Defense Science and Technology Conference, Orlando, FL, November 2010.

Makley M, Ruark C, Covington T, Robinson P, Gearhart J. Route of entry model for predicting chemical warfare agent miosis. Poster presented at the Chemical and Biological Defense Science and Technology Conference, Orlando, FL, November 2010.