Publications

Roberts DW, Api AM, Patlewicz G, Schultz TW. 2016. Chemical applicability domain of the Local Lymph Node Assay (LLNA) for skin sensitization potency. Part 1. Underlying physical organic chemistry principles and the extent to which they are represented in the LLNA validation dataset. Regul Toxicol Pharmacol 80(Oct):247-254; doi: 10.1016/j.yrtph.2016.07.007. PMID: 27424000.

Borghoff SJ, Ring C, Banton M, Leavens TL. 2016. Physiologically based pharmacokinetic model for ethyl tertiary-butyl ether and tertiary-butyl alcohol in rats: Contribution of binding to a2u-globulin in male rats and high-exposure nonlinear kinetics to toxicity and cancer outcomes.  J Appl Toxicol, DOI 10.1002/jat.3412

Worth A, Patlewicz G. 2016. Integrated approaches to testing and assessment. Adv Exp Med Biol 856:317-342; doi: 10.1007/978-3-319-33826-2_13. PMID: 27671729.

Patlewicz G, Worth AP, Ball N. 2016. Validation of computational methods. Adv Exp Med Biol 856:165-187; doi: 10.1007/978-3-319-33826-2_6. PMID: 27671722.

Ulrich K. Adversity and risk assessment of respiratory tract findings — A regulatory perspective. Presentation to the 31st Annual Meeting of the British Society of Toxicological Pathology (BSTP) — Association of Inhalation Toxicologists Joint Conference, Alderley Edge, Cheshire, UK, 2016.

Nicholson G, Gandra SR, Halbert RJ, Richhariya A, Nordyke RJ. 2016. Patient-level costs of major cardiovascular conditions: A review of the international literature. Clinicoecon Outcomes Res 21(8):495-506; doi: 10.2147/CEOR.S89331. PMID: 27703385.

Wirbisky SE, Sepúlveda MS, Weber GJ, Jannasch AS, Horzmann KA, Freeman JL. 2016. Embryonic atrazine exposure elicits alterations in genes associated with neuroendocrine function in adult male zebrafish. Toxicol Sci 153(1)149–164; doi: doi: 10.1093/toxsci/kfw115.

Bi P, Yue F, Karki A, Castro B, Wirbisky SE, Wang C, … Kuang, S. 2016. Notch activation drives adipocyte dedifferentiation and tumorigenic transformation in mice. J Exp Med 213(10):2019–2037.

Bi P, Yue F, Sato Y, Wirbisky S, Liu W, Shan T, Wen Y, Zhou D, Freeman J, Kuang S. 2016. Stage-specific effects of notch activation during skeletal myogenesis. Elife 5:e17355.

Garabrant DH, Alexander DD, Miller PE, Fryzek JP, Boffetta P, Teta MJ, … Kelsh MA, et al. 2016. Mesothelioma among motor vehicle mechanics: An updated review and meta-analysis. Ann Occup Hyg 60(1):8–26.

Lowe KA, Danese MD, Gleeson ML, Langeberg WJ, Kelsh MA. 2016. Racial and ethnic variability in the prevalence and incidence of comorbidities associated with gastric cancer in the United States. J Gastrointest Cancer 47(2):168–181; doi: 10.1007/s12029-016-9809-5.

Hummel HD, Topp MS, Chang ET, Chia VM, Kelsh MA, Doemland ML, et al. 2016. Adverse events in adults with relapsed or refractory acute lymphoblastic leukemia (ALL): A literature review of recent clinical trials. J Leuk 4(1):208; doi: 10.4172/2329-6917.1000208.

Erichsen R, Kelsh MA, Oliner KS, Nielsen KB, Frøslev T, Lænkholm AV, et al. 2016. Prognostic impact of tumor MET expression among patients with stage IV gastric cancer: A Danish cohort study. Annals of Epidemiol 26(7):500–503.

Gökbuget N, Dombret H, Ribera JM, Fielding AK, Advani A, Bassan R, … Kelsh M, et al. 2016. International reference analysis of outcomes in adults with B-precursor Ph-negative relapsed/refractory acute lymphoblastic leukemia. Haematologica 101(12):1524–1533; doi: 10.3324/haematol.2016.144311. PMID: 27587380.

Gökbuget N, Kelsh M, Chia V, Advani A, Bassan R, Dombret H, et al. 2016. Blinatumomab vs historical standard therapy of adult relapsed/refractory acute lymphoblastic leukemia. Blood Cancer J 6(9):e473.

Mackay CE, Vivanco SN, Yeboah G, Vercellone J. 2016. Assessment of dermal hazard from acid burns with fire retardant garments in a full-size simulation of an engulfment flash fire. Burns 42(6):1350–1356; doi: 10.1016/j.burns.2016.04.012.

Wikoff D, Borghoff S, Rager J, Harvey S, Haws L. 2016. A systematic review of the mechanistic evidence of tetrabromobisphenol TBBPA as a human carcinogen according to the ten key characteristics of carcinogens (TKCC) identified by Smith et al. (2016). PROSPERO 2016:CRD42016046429.

Kelsh MA. Evaluating biosimilars in observational data: Some methodological considerations. Presented at International Conference on Pharmacoepidemiology and Therapeutic Risk Management (ICPE), Dublin, Ireland, August 25–28, 2016.

Richard A, Judson R, Houck K, Grulke C, Volarath P, Thillainadarajah I, Yang C,…, Patlewicz G, et al. 2016. The ToxCast chemical landscape: Paving the road to 21st century toxicology. Chem Res Toxicol 29(8):1225-1251; doi: 10.1021/acs.chemrestox.6b00135. PMID: 27367298.

Shah I, Liu J, Judson RS, Thomas R, Patlewicz G. 2016. Systematically evaluating read-across prediction and performance using a local validity approach characterized by chemical structure and bioactivity information. Reg Toxicol Pharmacol 79(Aug):12-24; doi: 10.1016/j.yrtph.2016.05.008. PMID: 27174420.