2011 (76 POSTS)
Hale AC , Tries MA. 2011. Determination of 239 Pu airborne concentration alpha correction factor for a zinc sulfide detector via ambient 222 Rn progeny air sampling. Health Phys 100(2):201–209; doi: 10.1097/HP.0b013e3181e928a7 .
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Publication: Manuscripts
/ Topics: Radiation
Hinerman J , Herr A. Determining the mechanism of activation of glycoprotein VI. Poster presented to the Ohio Valley Crystallographic Symposium Meeting, Cleveland, OH, November 2011.
Publication: Abstracts and Presentations
/ Topics: mode of action
Hart BR, Mishra PK, Lintner RE, Hinerman JM , Herr AB, Blumenthal RM. 2011. Recognition of DNA by the helix-turn-helix global regulatory protein Lrp is modulated by the amino terminus. J Bacteriol 193(15):3794–3803; doi: 10.1128/jb.00191-11 . PMID: 21642464.
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Publication: Manuscripts
/ Topics: pharmacokinetics
Haws L, Proctor D, Thompson C , Harris M. Research plan to fill data gaps in the mode of action for cancer risk assessment of hexavalent chromium in drinking water. Presented at Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.
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Publication: Abstracts and Presentations
/ Topics: Cancer , chromium , water
Henderson RG , Cappellini D, Seilkop S, Oller A, Bates H. Bioaccessibility-based read-across assessment of nickel compounds for oral systemic toxicity. Presented at Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.
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Publication: Abstracts and Presentations
/ Topics: nickel
Urban JD , Rowlands JC, Budinsky RA. 2011. Single nucleotide polymorphisms in the human aryl hydrocarbon receptor nuclear translocator (ARNT) gene. Drug Metab Pharmacokinet 26(6):637-645; doi: 10.2133/dmpk.DMPK-11-SC-031 .
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Publication: Manuscripts
/ Topics: dioxin
Kim S, Thompson CM , Kopec AK, Harris MA, Zacharewski TR. Comparison of basal and CrVI-mediated solute carrier gene expression in rodent duodenal epithelium. Presented at Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.
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Publication: Abstracts and Presentations
/ Topics: chromium
Wilson VS, Keshava N, Hester S, Segal D, Chiu W, Thompson CM , Euling SY. 2013. Utilizing toxicogenomic data to understand chemical mechanism of action in risk assessment. Toxicol Appl Pharmacol 271(3):299–308; doi: 10.1016/j.taap.2011.01.017 .
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Publication: Manuscripts
/ Topics: risk assessment
Proctor D, Haws L , Thompson C , Harris M. 2011. Use of mode of action and pharmacokinetics to inform the cancer risk assessment of ingested Cr(VI): A case study. Presented at the Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.
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Publication: Abstracts and Presentations
/ Topics: Cancer , chromium , mode of action , pharmacokinetics , risk assessment
Proctor D, Meek B. Using mode of action data to guide quantitative cancer risk assessment: A case study of hexavalent chromium in drinking water. Presented at Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.
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Publication: Abstracts and Presentations
/ Topics: Cancer , chromium , mode of action , risk assessment , water
Staskal-Wikoff D , Budinsky R, Rowlands JC. Single nucleotide polymorphisms in the human aryl hydrocarbon receptor interacting protein (AIP) gene from six ethnic populations. Presented at Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.
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Publication: Abstracts and Presentations
/ Topics: toxicokinetics
Franke K , Paustenbach D. 2011. Government and Navy knowledge regarding health hazards of asbestos: A state of the science evaluation (1900 to 1970). Inhal Toxicol 23(S3):1–20; doi: 10.3109/08958378.2011.643417 .
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Publication: Manuscripts
/ Topics: asbestos , Exposure Assessment , risk assessment
2010 (67 POSTS)
Yong M, Kuehn C, Kelsh M , Mitchell M , et al. Associations between platelet count and survival and disease progression in thrombocytopenic patients with myelodysplastic syndromes. Presented at the American Society of Hematology, Orlando, FL, December 2010.
Publication: Abstracts and Presentations
/ Topics: Epidemiology
Daston GP, Chapin R, Scialli AR, Piersma AH, Carney EW, Rogers JM , Friedman JM. 2010. A different approach to validating screening assays for developmental toxicity. Birth Defects Res B 89(6):526–530. doi: 10.1002/bdrb.20276 . PMID: 21086491.
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Publication: Manuscripts
/ Topics: reproductive toxicology , test methods
Robison TW . Genotoxic impurity guidance – Current experiences, FDA perspective. USP Annual Meeting, New Orleans, LA, December 2010.
Publication: Abstracts and Presentations
/ Topics: genotoxicity
Tachovsky JA, Haws L . Geostatistical estimation of soil PCDD/F TEQ using sequential Gaussian simulation and the aggregation of results in Midland, MI. Presented at the Society for Risk Analysis Annual Meeting, Salt Lake City, UT, December 2010.
Publication: Abstracts and Presentations
/ Topics: dioxin
Mueser TC, Hinerman JM , Devos JM, Boyer RA, Williams KJ. 2010. Structural analysis of bacteriophage T4 DNA replication: Review in the Virology Journal series on bacteriophage T4 and its relatives. Virol J 7(Dec 3):359; doi: 10.1186/1743-422X-7-359 . PMID: 21129204.
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Publication: Manuscripts
/ Topics: modeling
Johns DO, Owens EO, Thompson CM , Sonawane B, Hattis D, Krishnan K. 2010. Physiological parameters and databases for PBPK modeling. Chapter 5 in: Quantitative Modeling in Toxicology. Krishnan K, Andersen M (eds.). Wiley, p. 107.
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Publication: Book Chapters
/ Topics: modeling , PBPK/PBDE
Harris M, Tachovsky JA, Staskal-Wikoff D , Aylward L, Burkhalter B, Simon T, Haws L . Serum concentrations of dioxin-like compounds in a population in Midland, Michigan: An evaluation of the impact of soil exposures. Presented at Dioxin 2010, San Antonio, TX, September 2010.
Publication: Abstracts and Presentations
/ Topics: dioxin
Sterner TR, Ruark CD, Covington TR , Hack CE, Gearhart JM. Characterizing uncertainty and population variability in a PBPK-PD mathematical model for the oxime HI-6. Poster presented at the Chemical and Biological Defense Science and Technology Conference, Orlando, FL, November 2010.