2021 (95 POSTS)
Rooney JP, Choksi NY , Ceger P, Daniel AB, Truax J, Allen D, Kleinstreuer N 2021. Analysis of variability in in vivo rabbit skin irritation assay results. Regul Toxicol Pharmacol 122(June):104920; doi: 10.1016/j.yrtph.2021.104920 . PMID: 33757807.
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Topics: NAMs , test methods
Clippinger AJ, Raabe HA, Allen DG, Choksi N , van der Zalm A, Kleinstreuer N, Barroso J, Lowit AB. 2021. Human-relevant approaches to assess eye corrosion/irritation potential of agrochemical formulations. Cutan Ocul Toxicol 40(2):145–167; doi: 10.1080/15569527.2021.1910291 . PMID: 33830843.
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Topics: Exposure Assessment
Proctor DM , Bhat V, Suh M , Reichert H , Jiang X , Thompson CM . 2021. Inhalation cancer risk assessment for environmental exposure to hexavalent chromium: Comparison of margin-of-exposure and linear extrapolation approaches. Regul Toxicol Pharmacol 124(August):104969; doi: 10.1016/j.yrtph.2021.104969 . PMID: 34089813.
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Topics: Cancer , chromium , Exposure Assessment , risk assessment
Belair DG, Sudak K, Connelly K, Collins ND , Kopytek SJ, Kolaja KL. 2021. Investigation into the role of ERK in tyrosine kinase inhibitor-induced neuropathy. Toxicol Sci 181(2):160–174; doi: 10.1093/toxsci/kfab033 . PMID: 33749749.
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Topics: toxicokinetics
Ring C, Sipes NS, Hsieh JH, Carberry C, Koval LE, Klaren WD , Harris MA, Auerbach SS, Rager JE. 2021. Predictive modeling of biological responses in the rat liver using in vitro Tox21 bioactivity: Benefits from high throughput toxicokinetics. Comput Toxicol 18(May):100166; doi: 10.1016/j.comtox.2021.100166 . PMID: 34013136.
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Topics: modeling , toxicokinetics
Cuellar AE, Adams LM, de Jonge E, Espina V, Espinoza L, Frankenfeld CL , Hines D, Kornienko O, et al. 2021. Protocol for the Mason: Health Starts Here prospective cohort study of young adult college students. BMC Public Health 21(1):897; doi: 10.1186/s12889-021-10969-5 . PMID: 33980206.
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Topics: community health , Epidemiology
Pradeep P, Judson RS, DeMarini DM, Keshava N, Martin TM, Dean J, Gibbons CF,…, Patlewicz G . 2021. An evaluation of existing QSAR models and structural alerts and development of new ensemble models for genotoxicity using a newly compiled experimental dataset. Comput Toxicol 18(May):100167; doi.org/10.1016/j.comtox.2021.100167 . PMID: 34504984.
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Topics: genotoxicity
Pan B, Kaldhone PR, Alund AW, Du H, Guo X, Yan J, Chen Y,…Robison TW , et al. 2021. Mutagenicity of silver nanoparticles evaluated using whole genome sequencing in mouse lymphoma cells. Nanotoxicol 15(3):418-432; doi: 10.1080/17435390.2021.1894614 . PMID: 33710943.
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Topics: nanomaterials
Mansouri K, Karmaus A, Fitzpatrick J, Patlewicz G , Pradeep P, Alberga D et al. 2021. CATMoS: Collaborative acute toxicity modeling suite. Environ Health Perspect 129(4):47013; doi: 10.1289/EHP8495 . PMID: 33929906.
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Topics: computational toxicology , modeling
Felter SP, Zhang X, Thompson C . 2021. Butylated hydroxyanisole: Carcinogenic food additive to be avoided or harmless antioxidant important to protect food supply? Regul Toxicol Pharmacol 121(April):104887; doi: 10.1016/j.yrtph.2021.104887 . PMID: 33556417.
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Topics: carcinogens , food additives , Food science
de Vries RBM, Angrish M, Browne P, Brozek J, Rooney AA, Wikoff DS , Whaley P, Edwards SW, et al. 2021. Applying evidence-based methods to the development and use of adverse outcome pathways. ALTEX 38(2):336–347; doi: 10.14573/altex.2101211 . PMID: 33837437.
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Topics: Adverse outcome pathways (AOPs) , Systematic Review
Choksi NY , Daniel AB, Allen DG, Clippinger AJ, Kleinstreuer NC. 2021. Prospective and retrospective evaluation of the eye irritation potential of agrochemical formulations. Research Triangle Park, NC: National Toxicology Program. NICEATM Report 01 .
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Topics: regulatory toxicology , test methods
Brodsky MB, Akst LM, Jedlanek E, Pandian V, Blackford B, Price C , et al. 2021. Laryngeal injury and upper airway symptoms after endotracheal intubation during surgery: A systematic review and meta-analysis. Anesth Analges 132(4):1023–1032; doi: 10.1213/ANE.0000000000005276 . PMID: 33196479.
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Topics: meta-analysis , Systematic Review
Whaley P, Blaauboer BJ, Brozek J, Cohen Hubal EA, Hair K, Kacew S,… , Wikoff D , Woodruff TJ. 2021. Improving the quality of toxicology and environmental health systematic reviews: What journal editors can do. ALTEX 38(3):513-522. doi: 10.14573/altex.2106111 . PMID: 34164697.
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Topics: Systematic Review
Dirven H, Vist GE, Bandhakavi S, Mehta J, Fitch SE , Pound P, Ram R, Kincaid B, Leenaars CHC, Chen M, Wright RA, Tsaioun K. 2021. Performance of preclinical models in predicting drug-induced liver injury in humans: A systematic review. Sci Reports 11(1)6403; doi: https://doi.org/10.1038/s41598-021-85708-2 . PMID: 33737635.
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Topics: modeling , Systematic Review
Haber LT, Reichard JF, Henning AK, Dawson P, Chinthraja RS, Sindher SB, Long A, Vincent MJ , et al. 2021. Bayesian hierarchical evaluation of dose-response for peanut allergy in clinical trial screening. Food Chem Toxicol 151(May):112125; doi: 10.1016/j.fct.2021.112125 . PMID: 33722597.
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Topics: Bayesian modeling , dose-response , Food science
Cherry D, Friedman E, Vincent M , Maier A. 2021. The legacy of weapons grade plutonium production: Health status of Hanford complex workers who manage the waste. Toxicol Ind Health 37(5):260–269; doi: 10.1177/0748233721996555 . PMID: 33853462.
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Topics: Radiation
Chew D, Sacks NC , Emden MR, Preib MT, Cyr PL , Wood D, Pokorney SD. 2021. Trends in health care resource use and expenditures in patients with newly diagnosed paroxysmal supraventricular tachycardia in the United States. Am Heart J 233(March):132–140; doi: 10.1016/j.ahj.2020.12.012 . PMID: 33359780.
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