2018 (32 POSTS)
Powles MA, Galgoci A, Misura A, Colwell L, Dingley K , Tang W, et al. 2018. In vivo efficacy of relebactam (MK-7655) in combination with imipenem/cilastatin in murine infection models. Antimicrob Agents Chemother 62:e02577–17; doi: 10.1128/AAC.02577-17 . PMID: 29866878.
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Topics: Toxicology
Liu W, Hussain Z, Zang Y, Sweis RF, Romero FA, Finke PE, … Dingley KH , et al. 2018. Optimization of preclinical metabolism for somatostatin receptor subtype 5-selective antagonists. ACS Med Chem Lett (9):1088–1093; doi: 10.1021/acsmedchemlett.8b00306 . PMID: 30429950.
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Topics: Toxicology
Fung ES, Unice KM, Paustenbach DJ, Finley BL , Kovochich M. 2018. Methods for sterilizing clinically relevant wear particles isolated from metal-on-metal hip implants. Sci Rep 8(1):2384.
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Topics: Toxicology
Barlow CA, Marsh GM, Benson S, Finley BL . 2018. The mineralogy and epidemiology of cosmetic talc. Toxicol Appl Pharmacol 361:173.
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Topics: Epidemiology
Kovochich M, Finley BL , Novick R, Monnot AD, Donovan E, Unice KM, Fung ES, Fung D, Paustenbach DJ. 2018. Understanding outcomes and toxicological aspects of second-generation metal-on-metal hip implants: A state-of-the-art review. Crit Rev Toxicol 48(10):839–887.
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Topics: Metals , Toxicology
Sacks NC , Sharma A, Cyr PL , Bertiger G, Dahdal DN, Brogadir S. 2018. Real-world comparison of the effectiveness and safety of different bowel preparation agents. Clin Exp Gastroenterol 11:289–299; doi: 10.2147/CEG.S171861 .
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Topics: Epidemiology
Sacks NC , Cyr PL , Louie AC, Liu Y , Chiarella MT, Sharma A, Chung KC. 2018. Burden of acute myeloid leukemia among older, newly diagnosed patients: Retrospective analysis of data from the 2010-2012 Medicare limited data set. Clin Ther 40(5):692–703.e2; doi: 10.1016/j.clinthera.2018.03.012 .
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Topics: Cancer , Health Economics and Outcomes Research (HEOR)
Wikoff DS , Miller GW. 2018. Systematic reviews in toxicology (Editorial). Toxicol Sci 163(2):335–337.
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Topics: Systematic Review , Toxicology
Ruzin A, Pastula ST , Levin-Sparenberg EM, Jiang X, Fryzek JP, Tovchigrechko A, Lu B, Qi Y, Liu H, Jin H, Yu L, Hackett J, Villafana T, Esser MT. 2018. Characterization of circulating RSV strains among subjects in the OUTSMART-RSV surveillance program during the 2016-17 winter viral season in the United States. PLoS One 13(7):e0200319; doi: 10.1371/journal.pone.0200319 .
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Topics: Epidemiology , Toxicology
Garabrant DH, Pastula ST . 2018. A comparison of asbestos fiber potency and elongate mineral particle (EMP) potency for mesothelioma in humans. Toxicol Appl Pharmacol 361(15 Dec):127–136; doi: 10.1016/j.taap.2018.07.003 .
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Topics: asbestos , mesothelioma , Toxicology
Thompson CT , Suh M , Chappell G, Borghoff S , Ellis-Hutchings, R, Wiench, K, Finch, L, Proctor, DM . 2018. Assessment of the mode of action underlying development of forestomach tumors in rodents following oral exposure to ethyl acrylate and relevance to humans. Regul Toxicol Pharmacol 96:178–189 doi: 10.1016/j.yrtph.2018.05.006.
Topics: PFAS , Toxicology
Suh M , Proctor DM , Chappell G, Rager JE, Thompson CM , Borghoff S , Finch L, Ellis-Hutchings R, Wiench K. 2018. A review of the genotoxic, mutagenic, and carcinogenic potentials of several lower acrylates. Toxicol 402-403(June 1):50-67; doi: 10.1016/j.tox.2018.04.006 .
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Topics: carcinogens , Toxicology
Proctor DM , Suh M , Chappell G, Borghoff SJ , Thompson CM , Wiench K, Finch L, Ellis-Hutchings R. 2018. An adverse outcome pathway (AOP) for forestomach tumors induced by non-genotoxic initiating events. Regul Toxicol Pharmacol, 96(July):30-40; doi: 10.1016/j.yrtph.2018.04.016 .
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Topics: Cancer , Toxicology
Thompson CM , Kirman CR, Hays SM, Suh M , Harvey SE , Proctor DM , Rager JE, Haws LC , Harris MA. 2018. Integration of mechanistic and pharmacokinetic information to derive oral reference dose and margin-of-exposure values for hexavalent chromium. J Appl Toxicol 38:351–365. doi: 10.1002/jat.3545 .
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Topics: Cr(VI) MOA Study , Hexavalent Chromium , pharmacokinetics
Pecquet AM, Martinez JM, Vincent M , Erraguntla N, Dourson M. 2018. Derivation of a no-significant-risk-level for tetrabromobisphenol A based on a threshold non-mutagenic cancer mode of action. J Appl Toxicol 38(6):862–878, doi: 10.1002/jat.3594.
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Topics: Toxicology
Haber LT, Dourson ML, Allen BC, Hertzberg RC, Parker A, Vincent MJ , et al. 2018. Benchmark dose (BMD) modeling: Current practice, issues, and challenges. Crit Rev Toxicol 48(5):387–415; doi: 10.1080/10408444.2018.1430121 .
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Topics: modeling , Toxicology
Caballero-Gallardo K, Wirbisky-Hershberger S , Olivero-Verbel J, de la Rosa J, Freeman JL. 2018. Embryonic exposure to an aqueous coal dust extract results in gene expression alterations associated with development and function of connective tissue and the hematological system, immunological and inflammatory disease and cancer in zebrafish. Metallomics 10(3):463–473
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Topics: Environmental Science
Bell SM, Chang X, Wambaugh JF, Allen DG, Bartels M, Brouwer … Choksi N , et al. 2018. In vitro to in vivo extrapolation for high throughput prioritization and decision making. Toxicol In Vitro 47:213–227; doi: 10.1016/j.tiv.2017.11.016 .
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Topics: risk assessment , Toxicology
Zhou W, Pal AS, Hsu AY, Gurol T, Zhu X, Wirbisky-Hershberger SE , Freeman JL, Kasinski AL, Deng Q. 2018. MicroRNA-223 supresses the canonical NF-kB pathway basal keratinocytes to dampen neutrophilic inflammation. Cell Reprod 13:1810–1823.
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