2006 (59 POSTS)
David RM, Clewell HJ, Gentry PR, Covington TR , Morgott DA, Marino DJ. 2006. Revised assessment of cancer risk to dichloromethane II. Application of probabilistic methods to cancer risk determinations. Regul Toxicol Pharmacol 45(1):55–65; doi: 10.1016/j.yrtph.2005.12.003 . PMID: 16439044.
View Abstract
Publication: Manuscripts
/ Topics: Cancer , PBPK/PBDE
Marino DJ, Clewell HJ, Gentry PR, Covington TR , Hack CE, David RM, Morgott DA. 2006. Revised assessment of cancer risk to dichloromethane: Part I Bayesian PBPK and dose-response modeling in mice. Regul Toxicol Pharmacol 45(1):44–54; doi: 10.1016/j.yrtph.2005.12.007 . PMID: 16442684.
View Abstract
Publication: Manuscripts
/ Topics: Bayesian modeling , Cancer , dose-response , modeling , PBPK/PBDE , risk assessment
Degregorio MW, Dingley KH , Wurz GT, Ubick E, Turteltaub KW. 2006. Accelerator mass spectrometry allows for cellular quantification of doxorubicin at femtomolar concentrations. Cancer Chemother Pharmacol 57(3):335-342; doi: 10.1007/s00280-005-0060-1 . PMID: 16047147.
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Publication: Manuscripts
/ Topics: Cancer , spectrometry
Tompkins EM, Farmer PB, Lamb JH, Jukes R, Dingley K , Ubick E, et al. 2006. A novel 14C-postlabeling assay using accelerator mass spectrometry for the detection of O6-methyldeoxy-guanosine adducts. Rapid Commun Mass Spectrom 20(5):883–891; doi: 10.1002/rcm.2370 . PMID: 16470516.
View Abstract
Publication: Manuscripts
/ Topics: spectrometry
Borowsky AD, Dingley KH , Ubick E, Turteltaub KW, Cardiff RD, Devere-White R. 2006. Inflammation and atrophy precede prostatic neoplasia in a PhIP-induced rat model. Neoplasia 8(9):708–715; doi: 10.1593/neo.06373 . PMID: 16984728.
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Publication: Manuscripts
/ Topics: carcinogens
Malfatti MA, Dingley KH , Nowell-Kadlubar S, Ubick EA, Mulakken N, Nelson D, Lang NP, et al. 2006. The urinary metabolite profile of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine is predictive of colon DNA adducts after a low-dose exposure in humans. Cancer Res 66(21):10541–10547; doi: 10.1158/0008-5472.CAN-06-1573 . PMID: 17079477.
View Abstract
Publication: Manuscripts
/ Topics: Cancer , carcinogens
Haws L . The use of toxic equivalency factors to assess potential human health risks posed by dioxin-like compounds: Keeping up with the science. Presented at Michigan State University, Toxicology Program Seminar Series, September,, 2006.
Publication: Abstracts and Presentations
/ Topics: dioxin , risk assessment
Wheeler MW , Park RM, Bailer AJ. 2006. Comparing median lethal concentration values using confidence interval overlap or ratio tests. Environ Toxicol Chem 25(5):1441-4; doi: 10.1897/05-320r.1. PMID: 16704080.
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Publication: Manuscripts
/ Topics: risk analysis , risk assessment
Buffler PA, Kelsh MA , Lau EC, Edinboro CH, Barnard JC, Rutherford GW, et al. 2006. Thyroid function and perchlorate in drinking water: An evaluation among California newborns, 1998. Environ Health Persp 114(5):798–804; doi: 10.1289/ehp.8176 . PMID: 16675440.
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Publication: Manuscripts
/ Topics: community health , risk assessment , water
Peabody JW, Nordyke RJ , Tozija F, Luck J, Muñoz JA, Sunderland A, Desalvo K, Ponce N, McCulloch C. 2006. Quality of care and its impact on population health: A cross-sectional study from Macedonia. Soc Sci Med 62(9):2216-24; doi: 10.1016/j.socscimed.2005.10.030 . PMID: 16289739.
View Abstract
Publication: Manuscripts
/ Topics: community health , Health Economics and Outcomes Research (HEOR)
Tinkelman DG, Price DB, Nordyke RJ , Halbert RJ, Isonaka S, Nonikov D, Juniper EF, Freeman D, et al. 2006. Symptom-based questionnaire for differentiating COPD and asthma. Respiration 73(3):296-305; doi: 10.1159/000090141 . PMID: 16330874.
View Abstract
Publication: Manuscripts
/ Topics: Epidemiology
Nordyke RJ , Chang CH, Chiou CF, Wallace JF, Yao B, Schwartzberg LS. 2006. Validation of a patient satisfaction questionnaire for anemia treatment, the PSQ-An. Health Qual Life Outcomes 4(May3):28; doi: 10.1186/1477-7525-4-28 . PMID: 16672069.
View Abstract
Publication: Manuscripts
/ Topics: Cancer , Health Economics and Outcomes Research (HEOR)
Leighton JK, Brown P, Ellis A, Harlow P, Harrouk W, Pine PS, Robison T , Rosario L, Thompson K. 2006. Workgroup Report: Review of genomic data based on experience with mock submissions: View of the CDER Pharmacology Toxicology Nonclinical Pharmacogenomics Subcommittee. Environ Health Perspect 114:573-578; doi: 10.1289/ehp.8318 . PMID: 16581548.
View Abstract
Publication: Manuscripts
/ Topics: drug development , nonclinical safety assessment , pharmacology
Lau C, Thibodeaux JR, Hanson RG, Narotsky MG, Rogers JM , Lindstrom AB, Strynar MJ. 2006. Effects of perfluorooctanoic acid exposure during pregnancy in the mouse. Toxicol Sci 90(2):510–518; doi: 10.1093/toxsci/kfj105 . PMID: 16415327.
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Publication: Manuscripts
/ Topics: PFAS
Staskal DF , Diliberto JJ, Birnbam LS. 2006. Disposition of BDE 47 in developing mice. Toxicol Sci 90(2):309-16; doi: 10.1093/toxsci/kfj098 . PMID: 16407092.
View Abstract
Publication: Manuscripts
/ Topics: flame retardants , PBPK/PBDE
Jackson MA, Lea I , Rashid A, Peddada SD, Dunnick JK. 2006. Genetic alterations in cancer knowledge system: Analysis of gene mutations in mouse and human liver and lung tumors. Toxicol Sci 90(2):400–418; doi: 10.1093/toxsci/kfj101 . PMID: 16410370.
View Abstract
Publication: Manuscripts
/ Topics: Cancer
Hamernik K, Eskes C, Merrill J, Choksi N , Allen D, Truax J, et al. 2006. ICCVAM-NICEATM-ECVAM symposium on mechanisms of chemically-induced ocular injury and recovery: Current understanding and knowledge gaps. ALTEX 23 Suppl:322–324 .
View Abstract
Publication: Abstracts and Presentations
/ Topics: Exposure Assessment
Covington TR , Gentry P, Van Landingham CB, Clewell HJ. Issues in using Markov Chain Monte Carlo analysis to calibrate a PBPK model for use in risk assessment: Case studies with dichloromethane and perchloroethylene. Poster presented at the Society of Toxicology Annual Meeting, San Diego, CA, March 2006.
Publication: Abstracts and Presentations
/ Topics: PBPK/PBDE
Richardson VM, Staskal DF , Diliberto JJ, Birnbaum LS. Effects of BDE 47 on nuclear receptor regulated genes and implications for thyroid hormone disruption. Society for Toxicology 45th Annual Meeting, San Diego, CA, March 2006.