2024 (157 POSTS)
Xue Y, Wang L, Huo R, Chen M, Melo B, Dingley K , et al. 2024. 1β-Hydroxydeoxycholic acid as an endogenous biomarker in human plasma for assessment of CYP3A clinical drug-drug interaction potential. Drug Metab Dispos 52(9):966–974; doi: 10.1124/dmd.124.001680 . PMID: 38991779.
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Publication: Manuscripts
/ Topics: biomarkers , drug interactions
Haselkorn T, Roca A, Miller B, Jensen I , Solomon F, Sanchez-de la Rosa R, Picart JM, Nascimento A. A real-world impact of X-linked myotubular myopathy (XLMTM) on caregivers in Spain. Presented at LXXVI Reunion Annual de la Sociedad Espanola de Nurologica, 19–23 November 2024.
Publication: Abstracts and Presentations
/ Topics: Health Economics and Outcomes Research (HEOR)
Monticello TM , Potter DM, Huang Q, Hart TK, Shuey D, Troth S, Vergis JM, Tassew N, et al. 2024. Do longer duration nonclinical toxicology studies provide predictive clinical safety value? The IQ Consortium longer duration nonclinical to clinical translational database. Toxicol Appl Pharmacol 492(Nov):117087; doi: 10.1016/j.taap.2024.117087 . PMID: 39243825.
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Publication: Manuscripts
/ Topics: nonclinical safety assessment
Fender CL , Good SP, Garcia-Jaramillo. 2024. An integrated approach to evaluating water contaminants and evaporation in agricultural water distribution systems. Ecotoxicol Environ Safety 287(15 Nov):117277; doi: 10.1016/j.ecoenv.2024.117277 . PMID: 39515202.
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Publication: Manuscripts
/ Topics: spectrometry , water
Pennell ML, Wheeler MW , Auerbach SS. 2024. A hierarchical constrained density regression model for predicting cluster‐level dose‐response. Environmetrics 35(7):e2880; doi: 10.1002/env.2880 . PMID: 40894950.
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Publication: Manuscripts
/ Topics: dose-response , modeling , transcriptomics
Bates CA, Vincent MJ , Buerger AN , Santamaria AB, Maier A, Jack M. 2024. Investigating the relationship between β-carotene intake from diet and supplements, smoking, and lung cancer risk. Food Chem Toxicol 194:115104; doi: 10.1016/j.fct.2024.115104 . PMID: 39522798.
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Publication: Manuscripts
/ Topics: Cancer , Food science
Haber LT, Bradley MA, Buerger AN , Behrsing H, Burla S, Clapp PW, et al. 2024. New approach methodologies (NAMs) for the in vitro assessment of cleaning products for respiratory irritation: Workshop report. Front Toxicol 6:1431790; doi: 10.3389/ftox.2024.1431790 . PMID: 39439531.
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Publication: Manuscripts
/ Topics: NAMs
Mattes RD, Rivera BN, Rutigliani GR, Rogers S , Mendoza ID, Wang L, Beckemeier K, Wikoff D . 2024. A review of low- and no-calorie sweetener safety and weight management efficacy. Nutrition Today 59(6):261-288; doi: 10.1097/NT.0000000000000723 .
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Publication: Manuscripts
/ Topics: Food science , nutrition , risk assessment
Gauthier A, Bare J, Kramer M . Tools and tips for exposure assessment throughout the product development life cycle. Education session, PSX 2024, Annual Conference of the Product Stewardship Society, Denver, CO, October 2024.
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Publication: Abstracts and Presentations
/ Topics: Exposure Assessment , Product Stewardship
Kelsh M , Bylsma LC, Jiang X, Movva N , Sacks NC . To be an orphan disease or not to be: An evaluation of prevalence estimates for cancers near the orphan status threshold and implications for orphan drug planning. International Society for Pharmacoepidemiology, 40th Annual Meeting, Berlin, Germany, August 2024.
Publication: Abstracts and Presentations
/ Topics: Epidemiology , Health Economics and Outcomes Research (HEOR)
Suh M, Mittal L, Brorby G, Pastula S, Vincent M, Proctor D . Epidemiology is critical in advancing cumulative impact assessment (CIA) research: A pilot study in San Antonio, Texas. International Society of Exposure Science, Montreal, Canada, October 2024.
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Publication: Abstracts and Presentations
/ Topics: Air Quality , Epidemiology
East A, Klaren W, Covington T, Rish W. Exploring biomarker-based methods to incorporate non-chemical stressor exposures into cumulative assessments for potentially vulnerable population groups. International Society of Exposure Science, Montreal, Canada, October 2024.
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Publication: Abstracts and Presentations
/ Topics: Air Quality , Epidemiology
Cook B, Nelms MD, Harris D, Bever RJ, Lynn SC, Borghoff S , et al. Clustering chemicals for predicting behavior and hazards: Insights from the endocrine disruptor screening program (EDSP) universe of chemicals. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.
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Publication: Abstracts and Presentations
/ Topics: Epidemiology , mode of action
Covington TR , Borghoff SJ , Bacigalupi L, O’Neal S, Cook B, Nelms M, et al. Prediction of chemical suitability for screening in a high-throughput assay platform using an in silico mass balance model. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.
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Publication: Abstracts and Presentations
/ Topics: modeling
Lea IA , Borghoff SJ, Chew R, Bell S, Edwards S, Vasko J, et al. Leveraging computational tools for enhanced human-in-the-loop systematic literature reviews. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.
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Publication: Abstracts and Presentations
/ Topics: Systematic Review
Holt JR, Chew RF, Bunnage E, Lea I, Borghoff SJ, Sayer R, et al. Categorizing articles for environmental health systematic evidence mapping: A zero-shot machine learning approach using large language models. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.
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Publication: Abstracts and Presentations
/ Topics: Health Economics and Outcomes Research (HEOR) , Systematic Review
Hampton LT, Kennedy SB , Barrick A, Wyler DB, Almroth BC, Coffin S, et al. The toxicity of microplastics explorer 2.0: Are we moving the needle forward on microplastics toxicity research? Abstract 7.03.T-05, Society of Environmental Toxicology and Chemistry 45th Annual Meeting, Fort Worth, TX, October 2024.
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Publication: Abstracts and Presentations
/ Topics: microplastics
Lane R, Gill S, Miller EL, Kennedy S , Shankar P, Williams T, et al. Rolling along: State of the science for tire related chemicals 6PPD and 6PPD-quinone. Abstract 4.22.P-Mo-115, Society of Environmental Toxicology and Chemistry 45th Annual Meeting, Fort Worth, TX, October 2024.
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Publication: Abstracts and Presentations
/ Topics: tire particles (TRWP)
Kennedy SB , Doyle D, Coffin S, Mair MM, Cowger W, Barrick A, et al. Trends in quality and risk assessment applicability of microplastic ecotoxicity studies. Abstract 7.03.P-Th-081, Society of Environmental Toxicology and Chemistry 45th Annual Meeting, Fort Worth, TX, October 2024.
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