Publications

Safe S, Harris MA, Biegel L, and Zacharewski T. 1991. Mechanism of Action of TCDD as an antiestrogen in transformed human breast cancer and rodent cell lines. Banbury Report 35: Biological Basis for Risk Assessment of Dioxins and Related Compounds Cold Spring Harbor Laboratory Press. 367-377.

Gillett J, Rish W (eds.). 1991. Risk and exposure assessment from toxic chemicals. Chapter 8 in Human health risks from chemical exposure: The Great Lakes ecosystem. Lewis Publishers, CRC Press.

Piskorska-Pliszczynska, J., B. Astroff, T. Zacharewski, M. Harris, R. Rosengren, V. Morrison, L. Safe, and S. Safe. 1991. Mechanism of action of 2,3,7,8-Tetrachlorodibenzo-p-dioxin Antagonists: characterization of [125I]-6-methyl-8-Iodo-1,3-dichlorodibenzofuran-Ah receptor complexes. Society of Toxicology 30th Annual Meeting. February 25-March 1, 1991. Dallas, TX.

Vater ST, Hollingsworth L, Baldwin DM, Warshawsky D. 1991. Comparative metabolism of 7,12-dimethylbenz[a]anthracene by the perfused liver and liver microsomal preparations from Sprague-Dawley rats. Carcinogenesis 12(12):2379–2382.

Vater ST, Baldwin DM, Warshawsky D. 1991. Hepatic metabolism of 7,12-dimethylbenz(a)anthracene in male, female, and ovariectomized Sprague-Dawley rats. Cancer Res 51(2):492–498.

Lea I, Moore HD, Latchman DS. 1991. Differential expression of the mouse U1a and U1b SnRNA genes is not dependent on sequence differences in the octamer motif. Biochem J 277( Pt 3):719–722.

Zacharewski T, Harris MA, and Safe S. 1991. Evidence for a possible mechanism of action of the 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated decrease of nuclear estrogen receptor levels in wild-type and mutant Hepa 1c1c7 cells. Biochem Pharmacol. 41:1931-1939.

Couture, L.A., M.W. Harris, A.M. Clark, and L.S. Birnbaum. 1990. Persistence of hydronephrosis in mice following in utero and/or lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Society of Toxicology Annual Meeting. February 12-16, 1990. Miami Beach, FL. The Toxicologist. 10:313.

Couture-Haws L, Abbott BD, and Birnbaum LS. 1990. A critical review of the developmental toxicity and teratogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin: recent advances in understanding the mechanism. Teratol. 42:619-627.

Harris M, Wenning R, Finley B, Paustenbach D. Evaluation of potential sources of 1,2,8,9-TCDD in aquatic biota from Newark Bay. Presented at Society of Environmental Chemistry and Toxicology 11th Annual Meeting. Washington, D.C., 1990.

Couture, LA, Harris MW, and Birnbaum LS. 1990. Characterization of the peak period of sensitivity for the induction of hydronephrosis in C57BL/6N mice following exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Fundam Appl Toxicol. 15:142-150.

Harris, M., T. Zacharewski, S. and Safe, S. 2,3,7,8-Tetrachlorodibenzo-p-dioxin as an antiestrogen: Effects of nuclear estrogen receptor levels in MCF-7 Cells. Society of Toxicology Meeting. February 12-16, 1990. Miami Beach, FL.

Harris MA, Piskorska-Pliszczynska J, Zacharewski T, and Safe S. 1990. Human breast cancer cell lines as models for investigating the effects of TCDD and related compounds. Chemosphere. 20(7-9):1135-1140.

McMillan DA, Lucas JB, Stotts J. Lack of IgE antibody to chlorhexidine in exposed populations. Toxicologist 10:220, 1990.

Zacharewski, T., J. Piskorska-Pliszczynska, F. Rosengren, B. Astroff, M. Harris, L. Safe, and S.Safe. 1990. 8-Iodo-1,3-dichlorodibenzofuran (I-MCDF) and 125I-MCDF as a 2,3,7,8-Tetrachlordibenzo-p-dioxin (TCDD) antagonist. Society of Toxicology Meeting. February 12-16, 1990. Miami Beach, FL.

Harris MA, Zacharewski T, Piskorska-Pliszcyznska J, Rosengren R, and Safe S. 1990. Structure-dependent induction of aryl hydrocarbon hydroxylase activity in C57BL/6 Mice by 2,3,7,8-tetrachlordibenzo-p-dioxin and related congeners: mechanistic studies. Toxicol Appl Pharmacol. 105:243-253.

Harris MA, Zacharewski T, and Safe S. 1990. Effects of 2,3,7,8-tetrachorodibenzo-p-dioxin and related compounds on the occupied nuclear estrogen receptor in MCF-7 human breast cancer cells. Cancer Res. 50:3579-3584.

Randerath K, Putman KL, Randerath E, Harris MA, Zacharewski T, and Safe S. 1990. Effects of 2,3,7,8-TCDD and related compounds on the levels of age-dependent I-spot DNA adducts in the liver of female and male Sprague-Dawley rats. Chemosphere 20(7-9):1049-1052.

Randerath K, Putman KL, Randerath E, Zacharewski T, Harris MA, and Safe S. 1990. Effects on 2,3,7,8-tetrachlorodibenzo-p-dioxin on I-compounds in hepatic DNA of Sprague-Dawley rats: sex specific effects and structure-activity relationships. Toxicol Appl Pharmacol. 103:271-280.

Safe S, Harris MA, Zacharewski T, and Biegel L. 1990. 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) as an antiestrogen in human breast cancer cells: mechanistic studies. Proceedings Dioxin `90, Eco-Informa Press. Bayreuth, Germany, 1:137-140.