2025 (50 POSTS)
Wikoff D . Pragmatic solutions for better using evidence-based methods to integrate observational data in food safety assessments. Toxicology Forum 2025 Winter Meeting, Raleigh, NC, February 2025.
Publication: Abstracts and Presentations
/ Topics: Food science , risk assessment
Lagiakos HR, Zou Y, Igawa H, Therrien E, Lawrenz M, Kato M, Svensson M, Gray F, Jensen K, Dahlgren M, Pelletier R, Dingley K, et al. 2025. In silico enabled discovery of KAI-11101, a preclinical DLK inhibitor for the treatment of neurodegenerative disease and neuronal injury. J Med Chem 68(3):2720-2741; doi: 10.1021/acs.jmedchem.4c02074 . PMID: 39670820.
View Abstract
Publication: Manuscripts
/ Topics: neurodegenerative disease
Borghoff SJ, Rivera B, Fitch S, Buerger AN, Choksi N, Franzen A, Vincent MJ, Covington T, Bus J, Rushton E, Lea IA . 2025. Systematic evaluation of the evidence base on methyl tert -butyl ether supporting a lack of concern for carcinogenic hazard in human based on animal cancer studies and mechanistic data. Curr Res Toxicol 8:100224; doi: 10.1016/j.crtox.2025.100224 . PMID: 40084233.
View Abstract
Publication: Manuscripts
/ Topics: Cancer , carcinogens , MTBE , risk assessment
Rogers JM, Buerger AN , Heintz MM , Palermo CM, Haws LC, Lea IA . 2025. Evaluation of a hypothesized Sertoli cell-based adverse outcome pathway for effects of diisononyl phthalate on the developing testis. Curr Res Toxicol 8:100219; doi: 10.1016/j.crtox.2025.100219 . PMID: 40123861.
View Abstract
Publication: Manuscripts
/ Topics: phthalates
Lea IA , Buerger AN , Feifarek D, Mihalchik A, Heintz MM, Haws LC , Nyambego H, Goyak K, Palermo C, Borghoff SJ . 2025. Evaluation of the endocrine disrupting potential of Di-isononyl phthalate. Curr Res Toxicol 8:100220; doi: 10.1016/j.crtox.2025.100220 . PMID: 40092461.
View Abstract
Publication: Manuscripts
/ Topics: phthalates
Kennedy SB, Heintz MM, Klaren WD, Wikoff DS, Haws LC, Fitch SE . 2025. An integrated ecotoxicological study reliability framework for use in toxicity value development. Environ Tox Chem 44(4):1142-1153; doi: 10.1093/etojnl/vgaf030 . PMID: 39873747.
View Abstract
Publication: Manuscripts
/ Topics: Ecology , risk assessment , Toxicology
Schaefer HR, Vincent MJ , Burns CJ, Lange SS. 2025. Increasing the utility of epidemiologic studies as key evidence in chemical risk assessment. Toxicol Sci 203(2):166-170; doi: 10.1093/toxsci/kfae134 . PMID: 39657235.
View Abstract
Publication: Manuscripts
/ Topics: Epidemiology , risk assessment
Zilber D, Messier KP, House J, Parham F, Auerbach SS, Wheeler MW . 2025. Bayesian gene set benchmark dose estimation for “omic” responses. Bioinformatics 41(1):btaf008; doi: 10.1093/bioinformatics/btaf008 . PMCID: PMC11783320.
View Abstract
Publication: Manuscripts
/ Topics: benchmark dose estimation (BMD) , Toxicology , transcriptomics
Rana Z, Frankenfeld CL , Kennedy E, Bertoldi J, de Jonge E, Cheskin L. 2025. Food sources of energy and nutrients among US college students: The Health Starts Here cohort study. J Am Coll Health 73(1):301-310; doi: 10.1080/07448481.2023.2220397 . PMID: 37290009.
View Abstract
Publication: Manuscripts
/ Topics: Epidemiology , Food science
Lipworth L, Panko JM , Allen BC, Mumma MT, Jiang X , Vincent MJ , Bare JL , Antonijevic T, Vivanco SN , Marano DE, Suh M , Cohen S, Mittal L , Proctor DM . 2025. Lung cancer mortality among aircraft manufacturing workers with long-term, low-level, hexavalent chromium exposure. J Occup Environ Hyg 22(3):214-227 ; doi: 10.1080/15459624.2024.2439817 . PMID: 39773194.
View Abstract
Publication: Manuscripts
/ Topics: Cancer , chromium , Exposure Assessment , Hexavalent Chromium , Occupational
2024 (120 POSTS)
Kim A, Cong Z, Jazieh A-R, Church TR, Reichert H , Nicholson G, Fryzek J, Cohen SS. 2024. Estimating the incremental population health impact of a multi-cancer early detection (MCED) test to complement existing screening among elevated risk populations with multiple cancer risk factors: A mathematical modeling study. BMC Health Serv Res 24(1):1584; doi: 10.1186/s12913-024-12037-1 . PMID: 39695574.
View Abstract
Publication: Manuscripts
/ Topics: Cancer , Epidemiology
Munn Z, Pollock D, Stone J, Hasanoff S, Gordon A, Price C, et al. 2024. The impact of using cannabis during pregnancy on the infant and mother: An overview of systematic reviews, evidence map, targeted updates, and de novo synthesis. Austral NZ J Obstet Gynaecol; doi: 10.1111/ajo.13916 . Online ahead of print, December 19, 2024.
View Abstract
Publication: Manuscripts
/ Topics: cannabis , Systematic Review
Olaye A, Bean K, Velikanova R, Wolters S, Miller B, Jensen I, Pang F. Cost-effectiveness of atidarsagene autotemcel (ARSA-CEL) gene therapy for treating metachromatic leukodystrophy (MLD) in Ireland, Belgium, and the Netherlands as a part of the Beneluxa Initiative. Abstract EE693 . ISPOR Europe 2024, November 2024.
View Abstract
Publication: Abstracts and Presentations
/ Topics: Metachromatic leukodystrophy (MLD)
Haselkorn T, Hughes W, Lennox A, Schara-Schmidt U, Roca A, Miller B, Jensen I , et al. Real-world impact of X-linked myotubular myopathy (XLMTM) on caregivers in the United Kingdom (UK), Germany, and Spain. ISPOR EU 2024 (Top 5% Finalist).
View Abstract
Publication: Abstracts and Presentations
/ Topics: XLMTM
Xue Y, Wang L, Huo R, Chen M, Melo B, Dingley K , et al. 2024. 1β-Hydroxydeoxycholic acid as an endogenous biomarker in human plasma for assessment of CYP3A clinical drug-drug interaction potential. Drug Metab Dispos 52(9):966–974; doi: 10.1124/dmd.124.001680 . PMID: 38991779.
View Abstract
Publication: Manuscripts
/ Topics: biomarkers , drug interactions
Haselkorn T, Roca A, Miller B, Jensen I , Solomon F, Sanchez-de la Rosa R, Picart JM, Nascimento A. A real-world impact of X-linked myotubular myopathy (XLMTM) on caregivers in Spain. Presented at LXXVI Reunion Annual de la Sociedad Espanola de Nurologica, 19–23 November 2024.
Publication: Abstracts and Presentations
/ Topics: XLMTM
Fender CL , Good SP, Garcia-Jaramillo. 2024. An integrated approach to evaluating water contaminants and evaporation in agricultural water distribution systems. Ecotoxicol Environ Safety 287(15 Nov):117277; doi: 10.1016/j.ecoenv.2024.117277 . PMID: 39515202.
View Abstract
Publication: Manuscripts
/ Topics: spectrometry , water , xenobiotics
Oller A, Barroso J, Prieto P, Verougstraete V, Heim K, Henderson R . 2024. Response to letter to editors submitted by PE Rasmussen, P Huntsman, TM Singer, MN Jacobs, and CC Trevithick-Sutton (Aug 2024). Regul Toxicol Pharmacol 154:105740; doi: 10.1016/j.yrtph.2024.105740 . PMID: 39557211.
Publication: Manuscripts
/ Topics: Metals
Pennell ML, Wheeler MW , Auerbach SS. 2024. A hierarchical constrained density regression model for predicting cluster‐level dose‐response. Environmetrics 35(7):e2880; doi: 10.1002/env.2880 .
View Abstract