2019 (165 POSTS)
Gentry R, Greene T, Granzen A, Thompson CM . Formaldehyde and leukemia: A case study using the IPCS MOA and human relevance frameworks. Poster at Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.
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Publication: Abstracts and Presentations
/ Topics: Cancer , formaldehyde
Urban J , Wikoff D , Suh M , Britt J , Harvey S , Chappell G, Haws L . Comparison of NTP OHAT and US EPA TSCA study quality criteria: Trichloroethylene (TCE) and congenital heart defects (CHDs) as a case study. Poster at Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.
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Publication: Abstracts and Presentations
/ Topics: trichloroethylene
McIntyre B, Zorilla L, Borghoff S , Foster P. Assessment of avobenzone, ensulizole, homosalate, and padimate-O in endocrine disruptor screening panel studies. Poster at Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.
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Publication: Abstracts and Presentations
/ Topics: safety assessment
Thompson CM , Gentry R. An updated mode-of-action analysis for formaldehyde-induced nasal tumors in rodents: A case study using the IPCS MOA and human relevance frameworks. Poster at Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.
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Publication: Abstracts and Presentations
/ Topics: formaldehyde , mode of action
Chappell GA, Rager JE, Wolf JC, Babic M, LeBlanc KJ, Ring CL, Harris MA, Thompson C . Similarities in the transcriptomic signatures in the duodenum of mice exposed to hexavalent chromium, captan, or folpet inform the mechanisms of chemical-induced mouse small intestine cancer. Presentation at Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.
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Publication: Abstracts and Presentations
/ Topics: Cancer , chromium , transcriptomics
Henderson RG , Doepker C , Lopez JG. Safety evaluation of L-theanine administered via hard chew to dogs. Poster at Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.
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Publication: Abstracts and Presentations
/ Topics: safety assessment
Pitts E, Gearhart JM, Covington TR , Duran CM, Yamamoto DP, McKenzie-Smith D, Ott DK, Pangburn HA. Thermal stress effects on physiologically based pharmacokinetic model for Department of Defense personnel. Poster presented at the Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.
Publication: Abstracts and Presentations
/ Topics: modeling , pharmacokinetics
Covington TR . Translating an existing physiologically-based pharmacokinetic model for isopropanol from a scalar to an array format. Poster presented at the Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.
Publication: Abstracts and Presentations
/ Topics: modeling , pharmacokinetics
Vincent MJ , Kozal SJ, Thompson WJ, Maier A, Dotson GS, Best EA, Mundt KA. 2019. Ethylene oxide: Cancer evidence integration and dose-response implications. Dose Response 17(4):1559325819888317; doi: 10.1177/1559325819888317 . PMID:3185323510.
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Publication: Manuscripts
/ Topics: Air Quality , Cancer
Visconti R, Foy J, Brennan S, Collins N , Kolaja K. An in vitro model of il-2-mediated Type 2 innate lymphoid cell proinflammatory cytokine secretion. Abstract #3377, Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.
Publication: Abstracts and Presentations
/ Topics: modeling
Belair DG, Waller L, Gustin J, Collins N , Kolaja K. Thalidomide inhibits human iPSC mesendoderm differentiation by modulating cereblon-dependent degradation of SALL4. Abstract #3296, Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.
Publication: Abstracts and Presentations
/ Topics: drug interactions
Sterner TR, Covington TR , Merrill EA, Mattie DR. Novel array approach to mixtures model streamlines predictions of cochlea and brain region tissue concentrations from JP-8 inhalation exposure. Poster presented at the Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.
Publication: Abstracts and Presentations
/ Topics: Exposure Assessment
Helman G, Shah I, Williams AJ, Edwards J, Dunne J, Patlewicz G . 2019. Generalized Read-Across (GenRA): A workflow implemented into the EPA CompTox Chemicals Dashboard. ALTEX 36(3):462-465; doi: 10.14573/altex.1811292 . PMID: 30741315.
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Publication: Manuscripts
/ Topics: NAMs
Borghoff SJ , Fitch S , Huggett D, Wikoff D . A hypothesis-driven weight-of-evidence analysis to evaluate potential endocrine disrupting properties of perfluorohexanoic acid (PFHxA). Poster at Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.
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Publication: Abstracts and Presentations
/ Topics: PFAS
Ring CL, Urban J , Wikoff D , Thompson C , Budinsky RA, Haws LC . Application of systematic review and quantitative evidence integration methods to support risk assessment: Characterization of the dose-response relationship between exposure to dioxin-like compounds (DLC) and sperm count. Poster at Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.
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Publication: Abstracts and Presentations
/ Topics: dioxin , risk assessment , Systematic Review
Lea I , Liu Y, Sheridan E, Motti D, Martini C, Fostel J, Auerbach S. Hallmark gene set annotation for NTP toxicogenomic studies. Abstract #1743-P119, Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.
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Publication: Abstracts and Presentations
/ Topics: genotoxicity
Martini C, Liu Y, Motti D, Johnson J, McCormick K, Lea I , Fostel F. Integrating assay datasets into Chemical Effects in Biological Systems (CEBS). Abstract #1749-P125, Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.
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Publication: Abstracts and Presentations
/ Topics: computational toxicology
Storm HM, Shepard J, Czerkies LM, Kineman B, Cohen SS, Reichert H , Carvalho R. 2019. 2’-Fucosyllactose is well tolerated in a 100% whey, partially hydrolyzed infant formula with Bifidobacterium lactis : A randomized controlled trial. Global Pediat Health 6(March 15):2333794X19833995; doi: 10.1177/2333794X19833995 . PMID: 30906817.
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Publication: Manuscripts
/ Topics: Food science
Preib M, Pokorney SD, Cyr PL , Everson K, Wood D, Sacks NC . Demographics and clinical characteristics of patients newly diagnosed with paroxysmal supraventricular tachycardia (PSVT). Poster presentation at European Heart Rhythm Society, Lisbon, Portugal, March 2019.